In vitro and in vivo characterization of novel magnesium alloy implants enhanced by hydrothermal and sol-gel treatments for bone regeneration [0.03%]
水热和溶胶-凝胶处理增强可降解镁合金体外及体内骨再生研究
Daniele Bellavia,Francesco Paduano,Silvia Brogini et al.
Daniele Bellavia et al.
Magnesium alloys are emerging as promising materials for biodegradable orthopedic implants due to their mechanical strength and biocompatibility. However, their clinical use is hindered by rapid degradation and hydrogen gas evolution, which...
Staying one step ahead of chronic wounds by designing symbiotic, responsive functionality into dynamic nanohydrogels [0.03%]
通过设计动态纳米水凝胶的共生性、响应性功能来保持对慢性伤口的一步领先优势
Ayushi Priyam,Lilith M Caballero Aguilar,Negar Mahmoudi et al.
Ayushi Priyam et al.
The dynamic environment of chronic wounds makes them an on-going clinical challenge. Conventional treatments often fail to respond to the pharmacological complexities of the system effectively, which compounded by ineffective pharmacokineti...
Dual antibacterial and antibiofilm strategy based on an injectable NO-releasing supramolecular hydrogel for periodontitis treatment [0.03%]
基于NO释放的可注射超分子水凝胶治疗牙周炎的抗菌抗生物膜双重策略
Lili Wang,Hong Chen,Dongna Xie et al.
Lili Wang et al.
Periodontitis, a microbially-driven chronic inflammatory disease intricately linked to systemic disorders, is conventionally managed through mechanical debridement supplemented with adjunctive antibiotic therapy. However, the anatomical com...
Sprayed antibacterial layer on titanium implants to eradicate biofilms by photoelectrons under near-infrared light [0.03%]
近红外光激发下纳米TiO2抗菌图层钛种植体的防菌研究
Junyu Dong,Shuqi Feng,Kai Wang et al.
Junyu Dong et al.
Infection induced by bacteria through biofilms can lead to implantation failure. Antibacterial implants against biofilms are being investigated, but the preparation conditions are sometimes challenging, especially when reactions occur on th...
Photo-regulated supramolecular artificial proton channels induce cancer cell apoptosis [0.03%]
光调控超分子人工质子通道诱导癌细胞凋亡
Tianlong Zhang,Yueyue Lu,Canhong Zhu et al.
Tianlong Zhang et al.
Natural channel proteins can effectively and selectively transport substances across membranes and control the opening and closing of channels under specific stimulation conditions, but achieving the same functions in artificial systems is ...
An AI-assisted multiplex fluorescence sensing platform for grading diagnosis of Alzheimer's disease [0.03%]
一种辅助AI的多重荧光检测平台用于阿尔茨海默病分级诊断
Yibiao Liu,Zhongzeng Zhou,Xingyun Liu et al.
Yibiao Liu et al.
Blood-based biomarkers have become increasingly important for Alzheimer's disease (AD) diagnosis. However, due to individual variations, diagnostic accuracy using a single blood biomarker remains low, making it challenging to implement in l...
Bacterial outer membrane vesicles in immune modulation: from mechanisms to applications [0.03%]
细菌外膜囊泡的免疫调节作用：从机制到应用
Yueqing Wang,Runhan Yang,Jun Luo et al.
Yueqing Wang et al.
Outer membrane vesicles (OMVs), naturally secreted by Gram-negative bacteria, have emerged as versatile tools for immune modulation due to their intrinsic immunogenicity and engineerable properties. This review explores how OMVs activate an...
Inducing ferroptosis in breast cancer with nanoparticles: a promising and challenging therapeutic strategy [0.03%]
用于乳腺癌治疗的纳米粒子诱导铁死亡：有前景且具挑战性的策略
Zhiyu Wang,Peiyao Xiao,Yuxuan Guo et al.
Zhiyu Wang et al.
Breast cancer, marked by its high global incidence and mortality rates, presents significant clinical challenges. Conventional treatments such as surgery, radiotherapy, chemotherapy, immunotherapy, and targeted therapy often fail to achieve...
A biocompatible, eco-friendly 3D-printed PCL-NIPUA resin for macular bucking devices in myopic tractional maculopathy [0.03%]
用于近视牵引性黄斑病的黄斑支撑装置的生物相容性和环保型3D打印PCL-NIPUA树脂
Zi Fu,Yan Zhou,Ziyi Liu et al.
Zi Fu et al.
Pathological myopia, characterized by excessive axial elongation, posterior staphyloma (PS) and retinal-choroidal degeneration, underlies sight-threatening conditions such as myopic traction maculopathy (MTM) and macular atrophy. Macular bu...
Bio-inspired rational design of multiscale topographical interfaces: pansy petal replicas as high-fidelity SERS platforms for single-cell analysis [0.03%]
受生物启发的多尺度拓扑界面的理性设计：作为单细胞分析高保真SERS平台的三色花瓣复制品
M Barshutina,Z Bochkova,I Zavidovskiy et al.
M Barshutina et al.
Engineering biointerfaces that provide both robust cell capture and optimal signal enhancement is a central challenge in the development of materials for cellular diagnostics. Conventional top-down fabrication methods are often complex and ...