Effect of β-Eudesmol on NQO1 suppression-enhanced sensitivity of cholangiocarcinoma cells to chemotherapeutic agents [0.03%]
β-艾术醇逆转NQO1低表达对胆管癌细胞化疗药物敏感性影响的作用及机制研究
Pimradasiri Srijiwangsa,Saranyoo Ponnikorn,Kesara Na-Bangchang
Pimradasiri Srijiwangsa
Background: Cholangiocarcinoma (CCA), an epithelial malignancy of the biliary tree, is one of the aggressive cancers with poor prognosis and unsatisfactory response to chemotherapy with acquired resistance. NAD(P)H-quinon...
Stent thrombosis associated with drug eluting stents on addition of cilostazol to the standard dual antiplatelet therapy following percutaneous coronary intervention: a systematic review and meta-analysis of published randomized controlled trials [0.03%]
替格瑞洛或西洛他唑添加至标准的双联抗血小板治疗用于药物洗脱支架植入后的随机对照试验中的药物洗脱支架内血栓形成：系统评价和meta分析
Feng Huang
Feng Huang
Background: In this analysis, we aimed to systematically compare stent thrombosis (ST) and its different subtypes following treatment with DAPT (aspirin + clopidogrel) versus TAPT (aspirin + clopidogrel + cilostazol). ...
Prescription opioid dispensing in New South Wales, Australia: spatial and temporal variation [0.03%]
澳大利亚新南威尔士州的处方阿片类药物发放：时空差异性
M Mofizul Islam,Ian S McRae,Soumya Mazumdar et al.
M Mofizul Islam et al.
Background: Patterns of opioid dispensing often exhibit substantial temporal and geographical variability, which has implications for public health policy decisions and interventions. The study examined recent trends in p...
The use of clonidine in elderly patients with delirium; pharmacokinetics and hemodynamic responses [0.03%]
氯代宁在老年谵妄患者中的使用：药动学和血流动力学反应
Karen Roksund Hov,Bjørn Erik Neerland,Anders Mikal Andersen et al.
Karen Roksund Hov et al.
Background: The Oslo Study of Clonidine in Elderly Patients with Delirium (LUCID) is an RCT investigating the effect of clonidine in medical patients > 65 years with delirium. To assess the dosage regimen and safety measu...
Randomized Controlled Trial
BMC pharmacology & toxicology. 2018 Jun 8;19(1):29. DOI:10.1186/s40360-018-0218-1 2018
Determinants of anti-retroviral regimen changes among HIV/AIDS patients of east and west Wollega zone health institutions, Oromia region, west Ethiopia: a cross-sectional study [0.03%]
西埃塞俄比亚奥罗米亚沃尔勒加区医疗机构HIV/AIDS患者抗逆转录病毒治疗方案变更的影响因素：一项横断面研究
Amsalu Bokore,Belay Korme,Getu Bayisa
Amsalu Bokore
Background: Human Immunodeficiency Virus (HIV) is one of the main causes of morbidity and mortality; because of this it continues to be a major global public health concern. It has believed to kill more than 34 million li...
Assessment of the state of pharmacovigilance in the South-South zone of Nigeria using WHO pharmacovigilance indicators [0.03%]
使用WHO药物警戒指标评估尼日利亚南部地区的药物警戒状况
Abimbola O Opadeyi,Annie Fourrier-Réglat,Ambrose O Isah
Abimbola O Opadeyi
Background: WHO pharmacovigilance indicators have been recommended as a useful tool towards improving pharmacovigilance activities. Nigeria with a myriad of medicines related issues is encouraging the growth of pharmacovi...
Grifolic acid induces GH3 adenoma cell death by inhibiting ATP production through a GPR120-independent mechanism [0.03%]
格拉夫酸通过GPR120非依赖机制抑制ATP产生诱导GH3腺瘤细胞死亡
Yufeng Zhao,Lei Zhang,Aili Yan et al.
Yufeng Zhao et al.
Background: Grifolic acid is a derivative of grifolin, an antitumor natural compound, and it was reported as an agonist of free fatty acid receptor GPR120. Little is known about its antitumor effects and the involvement o...
Absolute oral bioavailability and disposition kinetics of puerarin in female rats [0.03%]
女鼠口服大豆异黄酮皮素的绝对生物利用度及药动学研究
Tosapol Anukunwithaya,Pilaslak Poo,Natthaphon Hunsakunachai et al.
Tosapol Anukunwithaya et al.
Background: Pueraria candollei var. mirifica is a medicinal plant that is promoted as a "Champion Product" by the Government of Thailand. This plant has been reported to relieve postmenopausal symptoms, prevent and revers...
Antimicrobial resistance profile of Staphylococcus aureus isolated from patients with infection at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia [0.03%]
耐甲氧西林表皮葡萄球菌的分离鉴定及抗生素敏感性试验
Sileshi Tadesse,Haile Alemayehu,Admasu Tenna et al.
Sileshi Tadesse et al.
Background: Staphylococcus aureus is one of the major pathogens of public health importance responsible for various forms of infection. Development of resistance to commonly used antimicrobials limited treatment options a...
Adefovir dipivoxil induced hypophosphatemic osteomalacia in chronic hepatitis B: a comparative study of Chinese and foreign case series [0.03%]
阿德福韦致慢性乙肝患者低磷性骨软化症的中外病例对比研究
Nan Chen,Jian-Bo Zhang,Qiujie Zhang et al.
Nan Chen et al.
Background: Adefovir dipivoxil (ADV)-induced renal tubular dysfunction and hypophosphatemic osteomalacia (HO) have been given great consideration in the past few years. However, no standard guidance is available due to a ...