Development and validation of a nomogram for predicting thrombocytopenia in sepsis patients treated with linezolid [0.03%]
利福平治疗脓毒症患者血小板减少的预测列线图的建立和验证
Shu Yang,Lijun Hu,Guohua Liu et al.
Shu Yang et al.
A human liver organoids-on-chip for the assessment of drug-induced liver injury [0.03%]
一种评估药物性肝损伤的人类肝脏类器官芯片系统
Xiyue Chen,Fang Bao,Jiayue Liu et al.
Xiyue Chen et al.
Impact of aging on the pharmacokinetic profile of everolimus in male mice [0.03%]
老龄对小鼠体内everolimus药代动力学特征的影响
Dilek Ozturk Civelek,Ferdi Ozturk,Yasemin Kubra Akyel et al.
Dilek Ozturk Civelek et al.
Investigating the impact of gut microbiota-derived metabolites on benign prostatic hyperplasia using network pharmacology approaches [0.03%]
利用网络药理学方法研究肠道微生物群衍生代谢物对良性前列腺增生的影响
Yuanzhao Xu,Lingyue An,Jiling Xie et al.
Yuanzhao Xu et al.
Background: The gut microecosystem represents the most abundant and complex microbial ecosystem in the human body. Maintaining homeostasis of gut microbiota and their metabolites is essential for human health. As a chroni...
Integrated in silico and in vitro evaluation of Genistein and Apigenin as dual inhibitors of PARP1 and ESR1 in breast cancer [0.03%]
基因istein和Apigenin作为乳腺癌中PARP1和ESR1双重抑制剂的综合体内和体外评价
Monica Arora,Yahya S Yaseen,Ammar A Razzak Mahmood et al.
Monica Arora et al.
Background: Breast cancer remains a leading cause of cancer-related mortality among women worldwide, highlighting the need for safer multitarget therapies. Genistein (GNT) and Apigenin are plant-derived flavonoids with re...
Synergistic combination of pirfenidone and paclitaxel suppresses migration and stemness in triple-negative breast cancer: implications of EMT and pluripotency pathways [0.03%]
培非诺德尔和紫杉醇联合抑制三阴性乳腺癌的迁移和干细胞特性：上皮间质转化和多能性途径的意义
Nima Rastegar-Pouyani,Hamed Zare,Farnaz Rezaei et al.
Nima Rastegar-Pouyani et al.
Triple-negative breast cancer (TNBC) is an aggressive type of cancer with limited treatment options and high risks of metastasis and recurrence. Growing evidence shows that paclitaxel (PTX), a first-line chemotherapeutic agent in TNBC, may ...
Mangiferin: a novel hepatoprotective for liver cirrhosis via modulation of histological, cellular, biochemical, inflammatory markers and oxidative stress [0.03%]
mango酸通过调节组织学、细胞、生化、炎症标志物和氧化应激的新型保肝药用于肝硬化
Khaled Abdul-Aziz Ahmed,Suhayla Hamad Shareef,Haween Toufiq Nanakaly et al.
Khaled Abdul-Aziz Ahmed et al.
Integrative network toxicology, transcriptomic, and molecular docking approaches to elucidate the toxicity and mechanisms of bisphenol A in stroke [0.03%]
整合网络毒理学、转录组学和分子对接技术阐释双酚A在脑卒中发生中的毒性及机制
Zhonghui Wen,Bin Hu,Qiongfang Zhang et al.
Zhonghui Wen et al.
Evaluation of cut-off values in acute paracetamol poisoning for safe termination of N-acetylcysteine [0.03%]
急性对乙酰氨基酚中毒安全终止N-乙酰半胱氨酸治疗的截止值评估研究
Jeeyong Lim,Kyungman Cha
Jeeyong Lim
Zinc oxide resveratrol nanoparticles ameliorate levofloxacin-induced hepatotoxicity in rat model [0.03%]
纳米氧化锌白藜芦醇颗粒改善左氧氟沙星致大鼠肝毒性的研究
Naglaa F Zaki,Sahar H Orabi,Hend M Abdel-Bar et al.
Naglaa F Zaki et al.
Background: The present investigation assessed the potential ameliorating effect of zinc oxide resveratrol nanoparticles against Levofloxacin-induced liver damage in rats. ...