Extracellular histone H3 facilitates ferroptosis in sepsis through ROS/JNK pathway [0.03%]
组蛋白H3促进脓毒症中铁依赖性细胞死亡的新机制
Zhijun Han,Zhizhou Yuan,Linfei Shu et al.
Zhijun Han et al.
Introduction: Previous evidence realized the critical role of histone in disease control. The anti-inflammatory function of estradiol (E2) in sepsis has been documented. We here intended to unveil the role of extracellula...
Systemic lupus erythematosus associated with multiple myeloma: Two case reports and a literature review [0.03%]
系统性红斑狼疮合并多发性骨髓瘤的病例报告及文献复习
Li Lian,Kang Wang,Shengqian Xu
Li Lian
Introduction: Systemic lupus erythematosus (SLE) complicated by multiple myeloma (MM) is a relatively rare clinical presentation, and is easily ignored due to their similar or even identical manifestation, which may lead ...
Jian Zhang,Minglu Liu,Yin Chen et al.
Jian Zhang et al.
Background: With the rise of immunotherapy based on cancer neoantigen, identification of neoepitopes has become an urgent problem to be solved. The TP53 R273C mutation is one of the hotspot mutations of TP53, however, the...
Sevoflurane participates in the protection of rat renal ischemia-reperfusion injury by down-regulating the expression of TRPM7 [0.03%]
异氟醚通过下调TRPM7表达参与缺血再灌注损伤肾脏保护作用研究
Xudong Xu,Rongrong Deng,Lu Zou et al.
Xudong Xu et al.
Introduction: To investigate the protective effect of sevoflurane preconditioning on renal ischemia-reperfusion injury (renalischemiareperfusionmodel, RIRI) and its related mechanism. ...
Erik Wilhelm Vinnes,Birthe Skarbø,Tore Wentzel-Larsen et al.
Erik Wilhelm Vinnes et al.
Background: It is important and expected of laboratories to provide updated reference intervals to the clinician. As no recent publications report adult total IgE reference intervals on a Scandinavian population, the aim ...
STV-Na attenuates lipopolysaccharide-induced lung injury in mice via the TLR4/NF-kB pathway [0.03%]
STV-Na通过TLR4/NF-κB途径减轻脂多糖诱导的小鼠肺损伤
Yanhong Xu,Xiaoming Liu,Zhihui Zhang
Yanhong Xu
Background: Acute lung injury (ALI) is a potentially fatal disorder that is largely caused by inflammation. Sodium isostevanol (STV-Na) is a terpenoid produced from stevioside, which possesses anti-inflammatory and antiox...
lncRNA NEAT1/miR-495-3p regulates angiogenesis in burn sepsis through the TGF-β1 and SMAD signaling pathways [0.03%]
长链非编码RNA NEAT1通过调节miR-495-3p介导的TGF-β1和SMAD信号通路调控烧伤脓毒症血管生成
Yanbin Meng,Zhenming Hao,Hairui Zhang et al.
Yanbin Meng et al.
Introduction: To investigate the role of the long-chain noncoding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) in the process of angiogenesis in human umbilical vein endothelial cells (HUVECs) and illustrat...
Decreased antibody response to influenza vaccine with an enhanced antibody response to subsequent SARS-CoV-2 vaccination in patients with chronic hepatitis B virus infection [0.03%]
慢性乙型肝炎病毒感染患者接种流感疫苗后的抗体应答减弱和随后接种新冠病毒疫苗后的增强抗体应答
Taiyu He,Ning Ling,Gaoli Zhang et al.
Taiyu He et al.
Introduction: Influenza or SARS-CoV-2 vaccination is especially recommended for people with underlying diseases. For the large number of patients with chronic hepatitis B virus infection (CHB), studies on their immune res...
Knockdown of SEMA7A alleviates MPP+ -induced apoptosis and inflammation in BV2 microglia via PPAR-γ activation and MAPK inactivation [0.03%]
SEMA7A敲低通过激活PPAR-γ和抑制MAPK缓解MPP+诱导的BV2小胶质细胞凋亡及炎症反应
Weinan Qi,Dan Zeng,Xiaoshuan Xiong et al.
Weinan Qi et al.
Introduction: The inflammation mediated by microglial cells plays an important role in the process of neurodegenerative diseases. Recent evidence indicates that semaphorin 7A (SEMA7A) is implicated in various neurodegener...
Licorice protects against ulcerative colitis via the Nrf2/PINK1-mediated mitochondrial autophagy [0.03%]
甘草通过Nrf2/PINK1介导的线粒体自噬保护免受溃疡性结肠炎侵害
Jinrong Kong,Qingzhen Xiang,Gaoxiang Shi et al.
Jinrong Kong et al.
Purpose: Study of the effects and mechanisms of licorice in the treatment of ulcerative colitis (UC) from the perspective of mitochondrial autophagy. Meth...