Propolis Flavonoids Ameliorate Chronic Osteomyelitis in a Rat Model by Modulating TAZ-Regulated Treg/Th17 Balance [0.03%]
propolis黄酮通过调节TAZ调控的Treg / Th17平衡来改善慢性骨髓炎
Yujie Wang,Chaozhu Zhang,Zeyang He et al.
Yujie Wang et al.
Objective: To investigate the therapeutic mechanism of propolis flavonoids (PF) in chronic osteomyelitis (COM) through transcriptional coactivator with PDZ-binding motif (TAZ)-mediated regulation of regulatory T cell (Tre...
Systemic Inflammation and Central Neuronal Damage: The Relationship Between Neutrophil-to-Lymphocyte Ratio and Neuron-Specific Enolase in Acute Ischemic Stroke [0.03%]
炎症与中枢神经元损伤：急性缺血性脑卒中患者粒细胞与淋巴细胞比值与神经元特异性烯醇化酶的关系研究
Ning Rong,Hongyan Li,Siyu Qian et al.
Ning Rong et al.
Background and purpose: The systemic inflammatory response, quantified by the neutrophil-to-lymphocyte ratio (NLR), and central neuronal injury, reflected by serum neuron-specific enolase (NSE), are implicated in the path...
Epidemiological Trends and Clinical Characteristics of Epstein-Barr Virus Infection in Febrile Children in Zhejiang, China: A Retrospective Study [0.03%]
中国浙江省发热儿童Epstein-Barr病毒感染流行趋势及临床特征研究：回顾性研究
Hao Zhou,Xuanwen Ru,Wenqin Jin et al.
Hao Zhou et al.
Background: This study aimed to investigate the epidemiological trends, age- and sex-related patterns, and clinical and immunological characteristics of Epstein-Barr virus (EBV) infection among febrile children. ...
Exacerbated Hepatic Stress and Systemic Metabolic Disruption Driven by SARS-CoV-2 P.1 Variant in K18-hACE2 Mice [0.03%]
SARS-CoV-2 P.1变异毒株诱导的小鼠肝损伤及全身代谢紊乱
Monara Kaélle Sérvulo Cruz Angelim,Patrícia Brito Rodrigues,Antônio Thiago Pereira Campos et al.
Monara Kaélle Sérvulo Cruz Angelim et al.
Introduction: While severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been extensively studied in the context of pulmonary disease, its impact on metabolic organs remains poorly understood, particularly acr...
Dandruff Is a Low-Grade Inflammatory Condition Featuring Hyperproliferative Keratinocytes, Interleukin-17-Producing T Cells, and N-Acyl Ethanolamines [0.03%]
牛皮癣是一种轻度炎症，以增生的角质细胞、白介素-17生成T细胞和N-酰乙醇胺为特征
Alexandra C Kendall,Karishma Mohamed,Holly Linley et al.
Alexandra C Kendall et al.
Background: Dandruff features epidermal scaling but lacks overt signs of inflammation, such as erythema. Characterisation of its inflammatory profile may improve understanding of the underlying inflammatory mechanisms and...
Case Report of Combined Central and Peripheral Demyelination: Treated With Ofatumumab [0.03%]
奥法木单抗治疗中心性和周围神经脱髓鞘综合症病例报告
Lili Liu,Zhigang Zhong,Haijun Wu et al.
Lili Liu et al.
Background and objectives: Combined central and peripheral demyelination (CCPD) is a rare autoimmune-mediated disorder characterized by demyelination affecting both the central nervous system and peripheral nervous system...
Impaired IL-35/Treg Axis Facilitates Neuropathic Pain Via TNF-α, TLR4, and HMGB1 Activation [0.03%]
白介素-35/调节性T细胞轴功能障碍通过TNF-α、TLR4和HMGB1激活促进神经病理性疼痛
Pingdi You,Lirui Shen,Zhixiong Huang et al.
Pingdi You et al.
Background: Neuropathic pain (NP) is a chronic condition characterized by persistent pain due to dysfunction in the peripheral or central nervous system. Recent studies suggest immune dysregulation, particularly involving...
The Impact of Surfactant Protein-D Gene Polymorphism on COVID-19 Clinical Outcomes [0.03%]
肺表面活性物质蛋白D基因多态性与新冠肺炎临床结局的关系
Nadia Nasirzadeh Kolsari,Azarakhsh Azaran,Roya Pirmoradi et al.
Nadia Nasirzadeh Kolsari et al.
Background: COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), presents a broad spectrum of clinical manifestations, ranging from asymptomatic cases to severe, life-threatening respirato...
Mostafa Saebi,Amir Hossein Barjasteh,Mahmoud Mahmoudi et al.
Mostafa Saebi et al.
Cancer is a significant global health concern and ranks as the second most common cause of death on a worldwide scale. A combination of hereditary and lifestyle variables, such as diet, smoking, alcohol consumption, physical exercise, and t...