Deficiency of NF-Erythroid 2-Related Factor 2 Exacerbates the Scar Through ERK Signaling Pathway [0.03%]
缺NRF2通过ERK信号通路加重瘢痕形成缺陷
Xueyuan Hao,Mengke Sun,Ruotong Wang et al.
Xueyuan Hao et al.
Background: Scar, primarily composed of poorly structured and disordered collagen, is mainly characterized by excessive fibroblast activation and abnormal collagen deposition. Previous studies have shown that fibroblast a...
An In Silico Omics Investigation of the Lactobacillus Genus Complex for Allergenicity Mitigation [0.03%]
乳杆菌属益生菌低致敏株的组学筛选与验证研究
Zahra Bigdeli,Ali Molaei,Nassim Rahmani et al.
Zahra Bigdeli et al.
Background: Among the useful methods of immune response modulation, probiotics can be included. A delicate balance in the microbiome is of extreme importance for immune homeostasis, the composition of which is influenced ...
LSTM-Based Recurrent Neural Network Predicts Influenza-Like-Illness in Variable Climate Zones [0.03%]
基于LSTM的循环神经网络预测变化气候区的流感样疾病发病率
Alfred Amendolara,Christopher Gowans,Joshua Barton et al.
Alfred Amendolara et al.
Background: Influenza virus is responsible for a recurrent, yearly epidemic in most temperate regions of the world. Flu has been responsible for a high disease burden in recent years, despite the confounding presence of S...
Analgesic and Antidiarrheal Properties of Lappaconitine, Possibly Through Cyclooxygenase and µ-Opioid Receptor Interaction Pathways: In Vivo and In Silico Studies [0.03%]
延胡索甲素通过作用于环氧化酶和μ-阿片受体通路发挥镇痛和止泻的体内及分子机制研究
Shahid Shah,Arifa Akter,Salehin Sheikh et al.
Shahid Shah et al.
Background: Lappaconitine (LAP) is a diterpenoid alkaloid with strong anti-inflammatory activity. However, there is limited information on its gastroprotective effects. The present study aimed to explore the analgesic and...
Elevated Serum Lipopolysaccharides and Intrinsic Factor Autoantibodies Correlate With Macrocytic Anemia Among People With HIV [0.03%]
HIV患者巨幼细胞性贫血与血清脂多糖和内因子自身抗体升高有关
Daniel Amakye,Samuel Hammond,Osbourne Quaye et al.
Daniel Amakye et al.
Introduction: Human immunodeficiency virus (HIV) infection is associated with various comorbidities, including macrocytic anemia, though the role of the infection is unclear. HIV has been implicated in microbial transloca...
The Intersection of m6A Methylation and Immune Response in PCOS: A Bioinformatics Perspective [0.03%]
m6A甲基化与免疫反应在多囊卵巢综合征中的交集：生物信息学视角
Wenting Xu,Lingli Shi,Aifang Lu et al.
Wenting Xu et al.
Background: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder, the molecular underpinnings of which remain largely undefined. The most common methylation modification of RNA, N6-methyladenosine (m6A), pla...
Early Mortality Following Systemic Anticancer Therapy in Lung Cancer: A Bayesian Spatiotemporal Multilevel Analysis [0.03%]
肺癌全身抗肿瘤治疗后的早期死亡率：贝叶斯时空多水平分析
Getayeneh Antehunegn Tesema,Rob G Stirling,Win Wah et al.
Getayeneh Antehunegn Tesema et al.
Introduction: Despite advances in lung cancer treatment, early mortality following Systemic Anticancer Therapy (SACT) remains a major concern. Identifying patients at high risk of early mortality may inform treatment deci...
Clinical Analysis of Neonatal Influenza in the Neonatal Intensive Care Unit: A Retrospective Study [0.03%]
新生儿重症监护病房内新生儿流感的临床分析：回顾性研究
Min Zhou,Jia Chen,Jing Zhao et al.
Min Zhou et al.
Background: To describe the clinical characteristics, treatment, and outcomes of neonatal influenza. Methods: Retrospectively analyzed ...
Ginsenoside Rg3 Ameliorates Psoriasis-Like Dermatitis through Inhibition of NF-κB/NLRP3 Inflammasome Signaling and Regulating Th17/Treg Balance [0.03%]
Ginsenoside Rg3通过抑制NF-κB/NLRP3炎性小体信号及调控Th17/Treg平衡改善银屑病样皮炎
Liyun Gao,Qingge Xie,Zhaoli Zhou et al.
Liyun Gao et al.
Background: Psoriasis, characterized as a persistent cutaneous inflammatory condition driven by aberrant immunity, exhibits pathogenesis and disease course heavily influenced by sustained inflammatory activity. Ginsenosid...
Antibiotic Therapy and Factors Predicting Prolonged Hospitalization Among Children Under Three Years Diagnosed With Respiratory Syncytial Virus-Associated Lower Respiratory Infection [0.03%]
抗生素治疗和影响三岁以下呼吸道合胞病毒所致下呼吸道感染儿童住院时间延长的因素分析
Ali Alsuheel Asseri
Ali Alsuheel Asseri
Background: Respiratory syncytial virus (RSV) is a common cause of lower respiratory infections (LRIs) in infants and young children. Antibiotic overuse remains a significant concern in hospitalized children with RSV-asso...