Uric acid is independently associated with interleukin-1β levels in tear fluid of hyperuricemia and gout patients [0.03%]
尿酸独立于 interleukin-1β 水平在高尿酸血症和痛风患者泪液中的关联性
Mian Wu,Xingna Hu,Ting Lu et al.
Mian Wu et al.
Objectives: To explore pro-inflammatory cytokines status in the tear fluid of patients with hyperuricemia and gout and its association with uric acid level. ...
Juanfeng Lao,Zhi Xie,Qunshi Qin et al.
Juanfeng Lao et al.
Background: Psoriasis (PsO) is a T-cell-associated inflammatory autoimmune dermatitis. Leucine leucine-37 (LL-37) is upregulated in PsO patients and correlated with the area and severity of PsO. However, the exact relatio...
Association of ITM2A rs1751094 polymorphism on X chromosome in Korean pediatric patients with autoimmune thyroid disease [0.03%]
韩国儿童自身免疫性甲状腺疾病患者X染色体ITM2A基因rs1751094多态性的相关性研究
Won K Cho,In-Cheol Baek,Sung E Kim et al.
Won K Cho et al.
Background: Autoimmune thyroid disease (AITD) manifests with a female predominance, and much attention has been directed towards the integral membrane protein 2 A (ITM2A) gene located on the X chromosome. ...
Oral rehabilitation with dental implants in patients with systemic sclerosis: A systematic review [0.03%]
系统性硬化病患者种植体支抗口腔修复的系统评价研究
Seyed Ali Mosaddad,Reza Abdollahi Namanloo,Raziye Ghodsi et al.
Seyed Ali Mosaddad et al.
Objective: To assess the influence of systemic sclerosis (SSc) on the survival rate of dental implants in SSc patients receiving implant-supported treatments. ...
Identification of SARS CoV-2 Omicron BA.1 and a novel Delta lineage by rapid methods and partial spike protein sequences in Sulaymaniyah Province, Iraq [0.03%]
伊拉克苏莱曼尼亚省通过快速方法和部分刺突蛋白序列鉴定SARS-CoV-2奥密克戎BA.1和一个新的德尔塔谱系
Mariwan Kadir Rasheed,Harem Abdalla Awrahman,Sirwan M Amin Al-Jaf et al.
Mariwan Kadir Rasheed et al.
Background: Five variants of concern (VOCs) of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) have been globally recorded including Alpha, Beta, Gamma, Delta, and Omicron. The Omicron variant has outcompeted...
SIRT6 attenuates LPS-induced inflammation and apoptosis of lung epithelial cells in acute lung injury through ACE2/STAT3/PIM1 signaling [0.03%]
SIRT6通过ACE2/STAT3/PIM1信号通路抑制LPS诱导的急性肺损伤中肺上皮细胞的炎症和凋亡
Juan Yang,Xing Chen
Juan Yang
Background: Acute lung injury (ALI) is a severe and fatal respiratory disease. SIRT6 exerts pivotal activities in the process of lung diseases, but whether SIRT6 impacts ALI has not been covered. ...
Limonin ameliorates indomethacin-induced intestinal damage and ulcers through Nrf2/ARE pathway [0.03%]
柠檬素通过Nrf2/ARE途径改善吲哚美辛致肠损伤及溃疡的作用研究
Bo Jia,Leyi Zhao,Pengpeng Liu et al.
Bo Jia et al.
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) can cause intestinal damage and ulcers and the incidence is increasing. Limonin plays an important role in the regulation of inflammatory diseases, but it has not ...
PON2 ameliorates Ang II-induced cardiomyocyte injury by targeting the CANX/NOX4 signaling pathway [0.03%]
PON2通过靶向CANX/NOX4信号途径缓解Ang II诱导的心肌细胞损伤
Yuanzheng Ye,Jian Zhang,Yankai Guo et al.
Yuanzheng Ye et al.
Background: The incidence of heart failure (HF) presents an escalating trend annually, second only to cancer. Few literatures are available regarding on the role of paraoxonase 2 (PON2) in HF so far despite the protective...
Ononin alleviates DSS-induced colitis through inhibiting NLRP3 inflammasome via triggering mitophagy [0.03%]
オンオニン通过触发线粒体自噬抑制NLRP3炎性小体从而缓解DSS诱导的结肠炎
Ting Yu,Xuejia Lu,Yan Liang et al.
Ting Yu et al.
Background: Ononin, a flavonoid isolated from Astragalus membranaceus root, is the active ingredient of A. membranaceus and has potential anti-inflammatory properties, but its effect on colitis is unclear. ...
Yoshiyuki Abe,Nozomi Kawamata,Ayako Makiyama et al.
Yoshiyuki Abe et al.
Objectives: Lupus cystitis is a rare but serious complication of systemic lupus erythematosus (SLE) that can cause permanent bladder dysfunction, leading to irreversible deterioration of kidney function. We report two cas...