Profiling of innate and adaptive immune cells during influenza virus infection reveals sex bias in invariant natural killer T (iNKT) cells [0.03%]
流感病毒感染过程中先天性和适应性免疫细胞的图谱分析揭示了不变自然杀伤T(iNKT)细胞的性别偏向
Piotr Humeniuk,Aidan Barrett,Hannes Axelsson et al.
Piotr Humeniuk et al.
Background: Influenza A virus (IAV) infection leads to significant morbidity and mortality. Biological sex influences the immune responses to IAV infection, resulting in higher mortality in women of reproductive age. Prev...
Mixed storm in SARS-CoV-2 infection: A narrative review and new term in the Covid-19 era [0.03%]
SARS-CoV-2感染的混合风暴:新冠时代的叙事性综述和新术语
Basil Mohammed Alomair,Hayder M Al-Kuraishy,Ali I Al-Gareeb et al.
Basil Mohammed Alomair et al.
Coronavirus disease 2019 (Covid-19) is caused by a novel severe acute respiratory syndrome coronavirus virus type 2 (SARS-CoV-2) leading to the global pandemic worldwide. Systemic complications in Covid-19 are mainly related to the direct S...
Clinical characteristics and pathogen analysis of bronchoalveolar lavage fluid in elderly patients with community-acquired pneumonia [0.03%]
老年社区获得性肺炎患者临床特点及病原分析 Bronchoalveolar Lavage Fluid
Rui-Nan Guo,Zhang Dan,Zhu Fan et al.
Rui-Nan Guo et al.
Objective: To analyze the clinical characteristics and bronchoalveolar lavage fluid pathogens in elderly patients with community-acquired pneumonia (CAP). ...
Observational Study
Immunity, inflammation and disease. 2023 Apr;11(4):e813. DOI:10.1002/iid3.813 2023
Behçet syndrome: The disturbed balance between anti- (CLEC12A, CLC) and proinflammatory (IFI27) gene expressions [0.03%]
白塞氏综合症:抗炎(CLEC12A, CLC)和促炎基因(IFIG027)表达失衡所致
Ali Kemal Oğuz,Çağdaş Şahap Oygür,Seda Taşır et al.
Ali Kemal Oğuz et al.
Introduction: Behçet syndrome (BS) is a chronic, multisystemic inflammatory condition with unanswered questions regarding its pathogenesis and rational therapeutics. A microarray-based comparative transcriptomic analysis...
Organ-based clues for diagnosis of inborn errors of immunity: A practical guide for clinicians [0.03%]
基于器官的先天性免疫缺陷诊断线索:临床医师实用指南
Fatemeh Mohammadi,Amirhossein Yadegar,Mahta Mardani et al.
Fatemeh Mohammadi et al.
Inborn errors of immunity (IEI) comprise a group of about 490 genetic disorders that lead to aberrant functioning or the development of distinct immune system components. So far, a broad spectrum of IEI-related manifestations has been noted...
LncRNA TUG1 relieves renal mesangial cell injury by modulating the miR-153-3p/Bcl-2 axis in lupus nephritis [0.03%]
长链非编码RNA TUG1通过调节miR-153-3p/Bcl-2轴缓解狼疮性肾炎肾系膜细胞损伤
Lingxi Liu,Yanxia Zhang,Liping Zhong
Lingxi Liu
Background: Lupus nephritis (LN) is one of the most common and serious complications of systemic lupus erythematosus. Our experiments aimed to evaluate the molecular mechanisms of long noncoding RNA (lncRNA) TUG1 in a hum...
The validation of artificial anti-monkeypox antibodies by in silico and experimental approaches [0.03%]
基于计算和实验的体外人工抗猴痘病毒抗体验证研究
Sadeq Shabani,Mohsen Rashidi,Shakila Radgoudarzi et al.
Sadeq Shabani et al.
As a result of smallpox immunization programs that ended more than 40 years ago, a significant portion of the world's population is not immune. Moreover, due to the lack of anti-monkeypox drugs and vaccines against monkeypox, the spread of ...
Differences in allergen-specific basophil activation and T cell proliferation in atopic dermatitis patients with comorbid allergic rhinoconjunctivitis treated with a monoclonal anti-IL-4Rα antibody or allergen-specific immunotherapy [0.03%]
针对特应性皮炎伴发过敏性鼻结膜炎患者,使用抗IL-4Rα单克隆抗体或特异性免疫治疗的差异导致效应B细胞活化和T细胞增殖不同
Anne-Sophie Layritz,Jorge Galicia-Carreón,Said Benfadal et al.
Anne-Sophie Layritz et al.
Background: Atopic dermatitis (AD), a chronic inflammatory disorder, is often accompanied by allergic rhinoconjunctivitis (ARC) as a co-morbidity. The use of a monoclonal anti-IL-4Rα antibody has been effective in contro...
The potential role of SARS-CoV-2 infection in acute coronary syndrome and type 2 myocardial infarction (T2MI): Intertwining spread [0.03%]
SARS-CoV-2感染在急性冠脉综合征和二型心梗(T2MI)中的潜在作用:相互传播
Aseel Awad Alsaidan,Hayder M Al-Kuraishy,Ali I Al-Gareeb et al.
Aseel Awad Alsaidan et al.
Coronavirus disease 2019 (COVID-19) is a novel pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has been shown that SARS-CoV-2 infection-induced inflammatory and oxidative stress and associated endothelial...
Bone marrow stromal cell-derived exosomes improve oxidative stress and pyroptosis in doxorubicin-induced myocardial injury in vitro by regulating the transcription of GSDMD through the PI3K-AKT-Foxo1 pathway [0.03%]
骨髓基质细胞来源的外泌体通过PI3K-Akt-Foxo1信号通路调节GSDMD转录改善多柔比星致心肌损伤时的氧化应激和pyroptosis
Hong Zeng,Yong Yang,Fangfang Tou et al.
Hong Zeng et al.
Objectives: Doxorubicin (DOX) can contribute to severe myocardial injury, and bone marrow stromal cells (BMSC)-exosomes (Exos) improves acute myocardial infarction. Hence, this research investigated whether BMSC-Exos alle...