PCSK9 promotes T helper 1 and T helper 17 cell differentiation by activating the nuclear factor-κB pathway in ankylosing spondylitis [0.03%]
PCSK9通过激活核因子-κB途径促进强直性脊柱炎中T辅助1和T辅助17细胞分化
Jianfei Cai,Yinghui Jiang,Fucai Chen et al.
Jianfei Cai et al.
Objective: Our previous study reveals that proprotein convertase subtilisin/kexin type 9 (PCSK9) is positively related to inflammatory markers, T helper (Th)-17 cells, and treatment response in ankylosing spondylitis (AS)...
HIV and inflammatory markers are associated with persistent COVID-19 symptoms [0.03%]
与新冠肺炎长期症状相关的HIV和炎症标志物
Patrick Kamanzi,Gina Mulundu,Keagan Mutale et al.
Patrick Kamanzi et al.
Background: A proportion of COVID19 survivors may present with long-COVID, which is persistent symptoms lasting four or more weeks post SARS-CoV-2 infection. These symptoms may be mild to severe, and may affect different ...
Efficacy of diet restriction with or without probiotic for treatment of patients with IBS-D: Phase I-II clinical trial [0.03%]
益生菌联合饮食限制治疗肠易激综合征 диарейного типа临床I-II期试验疗效观察
Xian-Shu Zhao,Li-Jun Shi,Bao-Li Ning et al.
Xian-Shu Zhao et al.
Background and aim: Diet is a major contributor to irritable bowel syndrome (IBS) and is also a powerful tool for treatment of IBS. This study compared two diets and explored the effectiveness of the diets when combined w...
Randomized Controlled Trial
Immunity, inflammation and disease. 2023 May;11(5):e857. DOI:10.1002/iid3.857 2023
Inhibition of TMUB1 blocks apoptosis and NF-κB pathway-mediated inflammation in recurrent spontaneous abortion [0.03%]
TMUB1抑制能阻断复发性流产的凋亡和NF-κB介导炎症反应
Xiuping Zhang,Yuanjing Hu,Zhiping Zhang et al.
Xiuping Zhang et al.
Introduction: Approximately 50% of cases with recurrent spontaneous abortion (RSA) have unexplained etiology. Aberrant expression of transmembrane and ubiquitin-like domain containing 1 (TMUB1) is closely related to a ser...
Expression and significant roles of the lncRNA NEAT1/miR-493-5p/Rab27A axis in ulcerative colitis [0.03%]
长链非编码RNA NEAT1/miR-493-5p/Rab27A轴在溃疡性结肠炎中的表达及重要作用机制研究
Hecheng Wang,Jiadan Teng,Mingtao Wang et al.
Hecheng Wang et al.
Background: Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) have been reported to play regulatory roles in ulcerative colitis (UC). In this study, we aimed to determine the specific roles and action mechanism of the ...
Immunogenicity and safety of the BBIBP-CorV vaccine in patients with autoimmune inflammatory rheumatic diseases undergoing immunosuppressive therapy in a monocentric cohort [0.03%]
免疫抑制治疗中的自身免疫性炎症风湿病患者中BBIBP-CorV疫苗的免疫原性和安全性：单中心队列研究
Batool Zamani,Amin Moradi Hasan-Abad,Ahmad Piroozmand et al.
Batool Zamani et al.
Introduction: Vaccination plays a fundamental role in mastering the COVID-19 pandemic and protecting vulnerable groups. Persons with autoimmune inflammatory rheumatic diseases (AIIRD) requiring immunosuppressive therapies...
Acetic acid-induced colitis modulating potential of total crude alkaloidal extract of Picralima nitida seeds in rats [0.03%]
皮拉利玛树种子总生物碱对乙酸诱导的大鼠结肠炎的调节作用
Sarah A Otu-Boakye,Kofi O Yeboah,Eric Boakye-Gyasi et al.
Sarah A Otu-Boakye et al.
Purpose: The total crude alkaloidal extract of Picralima nitida seeds (PNE) is known to possess anti-inflammatory activity among other therapeutic benefits although its benefits in colitis has not been investigated. The c...
VPS72, a member of VPS protein family, can be used as a new prognostic marker for hepatocellular carcinoma [0.03%]
VPS72蛋白可作为肝细胞癌预后判断的新标志物
Jian Huang,Jin Gan,Jian Wang et al.
Jian Huang et al.
Background: Vacuolar protein sorting (VPS) plays a crucial role in intracellular molecular transport between organelles. However, studies have indicated a correlation between VPSs and tumorigenesis and the development of ...
Elevated levels of interleukin-33 are associated with asthma: A meta-analysis [0.03%]
白细胞介素-33与哮喘的相关性：一项荟萃分析
Ranran Zhao,Yun Shi,Na Liu et al.
Ranran Zhao et al.
Background: Previous studies reported that patients with asthma showed higher levels of interleukin (IL)-33 in peripheral blood, compared to healthy control (HCs). However, we also noticed that there were no significant d...
Luteolin suppresses inflammation and oxidative stress in chronic obstructive pulmonary disease through inhibition of the NOX4-mediated NF-κB signaling pathway [0.03%]
黄酮类化合物山柰酚通过抑制NOX4介导的NF-κB信号通路抑制慢性阻塞性肺疾病炎症和氧化应激作用
Mingfei Li,Huifang Wang,Yun Lu et al.
Mingfei Li et al.
Introduction: Chronic obstructive pulmonary disease (COPD) is associated with chronic inflammation that predominantly affects the lung and peripheral airways. Previous investigation has underlined the efficacy of luteolin...