Fibulin-2: A potential regulator of immune dysfunction after bone trauma [0.03%]
纤维蛋白-2：骨创伤后免疫功能障碍的潜在调节因子
Shidan Li,Hao Jiang,Shaochuan Wang et al.
Shidan Li et al.
Objectives: To reveal the relationship between the fibulin-2 protein and immune dysfunction after bone trauma. Methods: Individuals who...
Lijuan Du,Lu Tang,Lisha Xiao et al.
Lijuan Du et al.
Background: The link between colony-stimulating factor 1 (CSF1) and asthma was reported recently. However, the role and mechanism of CSF1 in asthma remain poorly understood. In this study, we aimed to explore the expressi...
Bo Cai,Shixue Chang,Yuhan Tian et al.
Bo Cai et al.
Hepatitis B virus (HBV) infection remains a global health challenge. Despite the availability of effective preventive vaccines, millions of people are at risk of cirrhosis and hepatocellular carcinoma. Current drug therapies inhibit viral r...
FBXW7 promotes autophagy and inhibits proliferation of oral squamous cell carcinoma [0.03%]
FBXW7促进口腔鳞状细胞癌的自噬及增殖抑制作用
Bo Qiu,Yang Sun,Wei Nie et al.
Bo Qiu et al.
Background: F-box and WD repeat domain containing 7 (FBXW7) is a critical tumor suppressor. The expression of FBXW7 is decreased in oral squamous cell carcinoma (OSCC) tissues and shows diagnosis value. We aimed to invest...
Phospholipase D2 targeted by miR-5132-5p alleviates cerulein-induced acute pancreatitis via the Nrf2/NFκB pathway [0.03%]
microRNA-5132-5p通过Nrf2/NF-κB信号通路靶向磷脂酶D2缓解急性胰腺炎
Hailong Wu,Hao Chen,Rui Zhou
Hailong Wu
Background: Acute pancreatitis (AP) is an inflammatory process unexpectedly occurring in the pancreas, imposing a substantial burden on healthcare systems. Herein, we aimed to clarify the mechanism of action of phospholip...
Galectin-9 and myeloid-derived suppressor cell as prognostic indicators for chronic lymphocytic leukemia [0.03%]
半乳糖凝集素-9和髓样衍生抑制细胞作为慢性淋巴细胞性白血病预后指标的影响
Xierenguli Alimu,Juan Zhang,Nannan Pang et al.
Xierenguli Alimu et al.
Background: Galectin-9 and myeloid-derived suppressor cells (MDSCs) have an important role in tumors, but their clinical values in chronic lymphocytic leukemia (CLL) have not been fully elucidated. This study aimed to ana...
COVID-19 as a trigger of Guillain-Barré syndrome: A review of the molecular mechanism [0.03%]
新型冠状病毒诱发吉兰-巴雷综合征的分子机制及其研究进展
Mahdi Malekpour,Shaghayegh Khanmohammadi,Mohammad Javad Entezari Meybodi et al.
Mahdi Malekpour et al.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a pandemic with serious complications. After coronavirus disease 2019 (COVID-19), several post-acute COVID-19 syndromes (PACSs) and long-COVID sequels were reported. PACSs ...
β-Glucan produced by Lentinus edodes suppresses breast cancer progression via the inhibition of macrophage M2 polarization by integrating autophagy and inflammatory signals [0.03%]
香菇产生的β-葡聚糖通过整合自噬和炎症信号抑制巨噬细胞M2极化来抑制乳腺癌进展
Fukai Zhu,Qianru Zhang,Jiexin Feng et al.
Fukai Zhu et al.
Background: β-Glucan from Lentinus edodes (LNT), an edible mushroom, possesses strong anticancer activity. However, the therapeutic effects of LNT during the occurrence and progression of breast cancer and their underlyi...
Mechanisms of ag85a/b DNA vaccine conferred immunotherapy and recovery from Mycobacterium tuberculosis-induced injury [0.03%]
Ag85A/B基因工程DNA疫苗治疗结核感染的机制研究及其对宿主肺组织损伤修复的影响zychenggang123456补充：基于Ag85A/B基因工程DNA疫苗诱导免疫治疗对宿主抗结核感染及肺部组织损伤修复影响的研究
Nan Wang,Yan Liang,Qianqian Ma et al.
Nan Wang et al.
Our previous research developed a novel tuberculosis (TB) DNA vaccine ag85a/b that showed a significant therapeutic effect on the mouse tuberculosis model by intramuscular injection (IM) and electroporation (EP). However, the action mechani...
Biological research on the occurrence and development of multiple myeloma and its treatment [0.03%]
生物医学领域多发性骨髓瘤的发生发展及治疗研究进展
Yue Wu,Xiangjun Shi,Xinchen Yao et al.
Yue Wu et al.
Introduction: To review the pathogenesis and treatment of multiple myeloma (MM). MM is a hematological malignancy with abnormal plasma cell proliferation in bone marrow. Due to the emergence of drug resistance, MM is stil...