Th17/Treg balance is regulated by myeloid-derived suppressor cells in experimental autoimmune myocarditis [0.03%]
心肌炎动物模型中髓系来源的抑制性细胞调节Th17/Treg平衡
Xin Xiong,Mengjia Yu,Dinghang Wang et al.
Xin Xiong et al.
Objective: Autoimmune myocarditis is caused by both innate and adaptive immune responses. Many studies have found that myeloid-derived suppressor cells (MDSCs) suppress T-cell responses and reduce immune tolerance, while ...
NEAT1 enhances MPP+ -induced pyroptosis in a cell model of Parkinson's disease via targeting miR-5047/YAF2 signaling [0.03%]
NEAT1通过靶向miR-5047/YAF2信号途径增强MPP+诱导的细胞帕金森病模型中的pyroptosis
Hong Shen,Hui Song,Songlin Wang et al.
Hong Shen et al.
Purpose: Parkinson's disease (PD) is the second most frequent neurodegenerative disease. The aim of our study is to explore the role and the regulatory mechanism of long noncoding RNA (lncRNA) NEAT1 in MPP+ -induced pyrop...
Prevalence and complication of COVID-19 in patients with ankylosing spondylitis (AS) and its relationship with TNF-a inhibitors [0.03%]
新型冠状病毒肺炎在强直性脊柱炎患者中的发病情况及与TNF-α抑制剂的关系研究
Shafieh Movassaghi,SeyedAhmad SeyedAlinaghi,Abdolrahman Rostamian et al.
Shafieh Movassaghi et al.
Introduction: Ankylosing spondylitis (AS) is a condition that is treated with nonsteroidal anti-inflammatory drugs and biological drugs such as anti tumor necrosis factor alpha (TNF-α). This study examined the prevalence...
Investigating the role of Zibai ointment on apoptosis-related factors Bcl-2 and Bax in wound healing after anal fistula surgery [0.03%]
调查滋白软膏对肛瘘术后创面愈合相关凋亡因子Bcl-2和Bax的影响研究
Er-Wei Cai,Cheng Zhao,Wei-Juan Wang et al.
Er-Wei Cai et al.
Objective: In this study, we investigated the impact of Zibai ointment on wound healing by analyzing the expression levels of two key apoptosis-related factors-B-cell lymphoma 2 (Bcl-2) and Bcl-2-associated X protein (Bax...
Randomized Controlled Trial
Immunity, inflammation and disease. 2023 Jun;11(6):e912. DOI:10.1002/iid3.912 2023
The effect of oral probiotics on CD4 count in patients with HIV infection undergoing treatment with ART who have had an immunological failure [0.03%]
口服益生菌对接受抗逆转录病毒治疗且免疫重建失败的HIV感染者CD4计数的影响
Masoud Mortezazadeh,Saeed Kalantari,Nooshin Abolghasemi et al.
Masoud Mortezazadeh et al.
Introduction: Probiotics are live microorganisms that, when administered in appropriate colonies, can delay the destruction of the immune system and contribute to the maintenance of immunity in HIV patients. Probiotics pl...
Randomized Controlled Trial
Immunity, inflammation and disease. 2023 Jun;11(6):e913. DOI:10.1002/iid3.913 2023
Characterization of SARS-CoV-2 humoral immune response in a subject with unique sampling: A case report [0.03%]
SARS-CoV-2血清学独特的采样间隔下的免疫应答特征——一例报告
Melanie R Walker,Manja Idorn,Anja Bennett et al.
Melanie R Walker et al.
Background: The development of vaccine candidates for COVID-19, and the administration of booster vaccines, has meant a significant reduction in COVID-19 related deaths world-wide and the easing of global restrictions. Ho...
Acceptance, availability, and feasibility of RTS, S/AS01 malaria vaccine: A review [0.03%]
RTS?, S/AS01疟疾疫苗的接受度、可及性和可行性：综述
Hassan Mumtaz,Abdullah Nadeem,Wajeeha Bilal et al.
Hassan Mumtaz et al.
Introduction: In malaria-stricken regions, malaria continues to be one of the primary causes of mortality for children. The number of malaria-related fatalities has drastically decreased because of artemisinin-based pharm...
Fangfang Yuan,Junhong He,Jing Luo et al.
Fangfang Yuan et al.
Background: As a new immunomodulator for rheumatoid arthritis, iguratimod (IGU) also has therapeutic potential in other immune diseases. In this study, we determined the effects of IGU on disease control in patients with ...
Allergen-specific immunotherapy by recombinant Der P1 allergen-derived peptide-based vaccine in an allergic mouse model [0.03%]
基于尘螨Der p1过敏原衍生肽的重组疫苗治疗过敏小鼠模型
Soheila Asoudeh Moghanloo,Mohsen Forouzanfar,Mojtaba Jafarinia et al.
Soheila Asoudeh Moghanloo et al.
Aim: Increased IgE levels have made house dust mite allergens one of the most frequent causes of allergies worldwide. Treatment reduces the IgE antibodies and types two cytokines, namely interleukin-4 (IL-4) and IL-13. Al...
YES-associated protein-regulated Smad7 worsen epithelial barrier injury of chronic sinusitis with nasal polyps [0.03%]
YES相关蛋白调控的Smad7加重慢性鼻窦炎伴鼻息肉上皮屏障损伤
Xiaocong Jiang,Longlan Shu,Yijun Liu et al.
Xiaocong Jiang et al.
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) was potentially due to the epithelial barrier injury. YES-associated protein (YAP) is a multifunctional transcriptional factor and plays versatile roles in the...