Safety and Efficacy of Obinutuzumab in Treating Lupus Nephritis: A Systematic Review [0.03%]
奥比妥珠单抗治疗狼疮性肾炎的安全性和有效性：系统评价
Zainab Arif,Hafsa Ali,Erum Siddiqui et al.
Zainab Arif et al.
Background: Lupus nephritis (LN) is a serious manifestation of systemic lupus erythematosus (SLE), often leading to end-stage renal disease. Despite current immunosuppressive therapies, complete renal remission remains li...
The Bufei Nashen Pill Alleviates COPD by Targeting Endoplasmic Reticulum Stress Through the PERK/eIF2α Signaling Pathway [0.03%]
补肺纳肾方通过激活PERK/eIF2α信号通路抑制内质网应激治疗慢性阻塞性肺疾病
Tengfei He,Anni Zhang,Changxi Zhang
Tengfei He
Background: Evidence supporting the therapeutic efficacy of Bufei Nashen pill (BFNSP) for chronic obstructive pulmonary disease (COPD) is currently limited. We evaluated BFNSP's effects on COPD progression and elucidated ...
Exosomal miR-1246 in Syphilis Serofast State: Diagnostic Value and NLRP3 Inflammasome Suppression [0.03%]
梅毒血清固定状态外泌体miR-1246的诊断价值及NLRP3炎性小体抑制作用研究
Yue Mou,Caifeng He,Fanxiang Wang et al.
Yue Mou et al.
Background: Serofast state (SF), defined as persistent low-titer antibodies after treatment, poses a diagnostic challenge because of the overlap with serologic features of active infection. Exosomal miRNAs are stable in b...
Relationship Between IL6/IL10 Serum Concentrations and Organ Function in Critically Ill Patients Based on Sepsis: A Prospective Study [0.03%]
基于脓毒症的危重症患者脏器功能与血清IL6/IL10水平关系的前瞻性研究
Guang-Jian Wang,Hui Lian,Hong-Min Zhang et al.
Guang-Jian Wang et al.
Background: Critical illnesses, particularly sepsis with accompanying organ dysfunction, significantly increase patient mortality. The imbalance between pro-inflammatory and anti-inflammatory responses is closely linked t...
A Nomogram Based on the Castelli Risk Index for Predicting Prognosis in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: A Cohort Study [0.03%]
基于卡斯特利风险指数的急性冠脉综合征经皮冠状动脉介入患者的预后预测列线图：队列研究
Yan Liu,Ge Song,Ying Zhang et al.
Yan Liu et al.
Background and aims: Composite lipid indices are closely related to the risk and poor prognosis of diseases. However, there are no studies on the prognostic value of Castelli's risk indices-I and II (CRI-I, CRI-II) in pat...
Identification of Prognostic Values of Neutrophil Extracellular Traps-Related Genes in Glioma Based on Bioinformatics [0.03%]
基于生物信息学的胶质瘤中鉴定NETs相关基因的预后价值
Xiaobing Guo,Xiaowen Li,Hengxi Li et al.
Xiaobing Guo et al.
Background: Glioma is a highly invasive and drug-resistant malignant primary tumor. Increasing research is focusing on the function of neutrophil extracellular traps (NETs) in glioma progress. We aimed to explore the mech...
Post-COVID-19 Area Postrema Syndrome With SARS-CoV-2 in CSF: A Dual-Case Report and Review of the Literature [0.03%]
新冠疫情后的下延脑综合症伴脑脊液中SARS-CoV-2: 两例报告及文献回顾
Wan Zhu,Jing Qian,Min Peng et al.
Wan Zhu et al.
Background: Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune astrocytopathy characterized by inflammatory demyelinating lesions in the central nervous system. Area postrema syndrome (APS), marked by int...
Hyperoside Modulates the Estrogen-PI3K/VEGF Axis to Ameliorate Oxidative Damage-Induced Inhibition of Bone Formation in MC3T3-E1 Cells [0.03%]
hyperoside通过调节雌激素-PI3 K / VEGF轴改善氧化损伤引起的MC3T3-E1细胞成骨抑制作用
Shuo Wang,Wei Feng,Xueqin Feng et al.
Shuo Wang et al.
Objective: This study aims to investigate how hyperoside (HYP) alleviates oxidative stress-induced osteoporosis, its molecular mechanisms, and its impact on osteoblast differentiation, oxidative damage, and the estrogen-P...
Clinical Value the Neutrophil CD64 Index in Predicting the Severity of Hemorrhagic Fever With Renal Syndrome [0.03%]
预测肾综合征出血热严重程度的中性粒细胞CD64指数的临床价值
Chuantao Ye,Rongrong Zhang,Shasha Wu et al.
Chuantao Ye et al.
Objective: The hemorrhagic fever with renal syndrome (HFRS) is an acute viral infectious disease characterized by multi-system damage involving complex mechanisms. Effective identification of critically ill patients is es...
Polydatin Relieves Airway Remodeling by Inhibiting P2X7R-NLRP3-Mediated Excessive Autophagy in Asthma [0.03%]
聚独氧茋通过抑制P2X7R-NLRP3介导的过度自噬防治哮喘气道重塑
Guangxing Li,Liangchang Li,Zhiguang Wang et al.
Guangxing Li et al.
Background: Asthma is characterized by chronic airway inflammation and remodeling. Polydatin (PD), a natural compound, has shown anti-inflammatory potential, but its role in asthma-related airway remodeling and the underl...