Predictive Value of the Systemic Immune-Inflammation Index for the Clinical Efficacy of Acupuncture and Exercise Rehabilitation in Knee Osteoarthritis: A Retrospective Study [0.03%]
系统免疫炎症指数对膝骨关节炎针刺联合康复疗效预测价值的回顾性研究
Shifei Sun,Zhiyong Lu,Qing Yang et al.
Shifei Sun et al.
Objective: To evaluate the predictive value of the systemic immune-inflammation index (SII) for clinical efficacy of acupuncture combined with exercise rehabilitation in patients with knee osteoarthritis (KOA). ...
Observational Study
Immunity, inflammation and disease. 2026 May;14(5):e70430. DOI:10.1002/iid3.70430 2026
Peripheral Blood Biomarkers Predict Outcomes in Advanced Cancers Treated With Anti-PD-1 Therapy [0.03%]
外周血生物标志物可预测抗PD-1治疗晚期癌症的疗效
Chunxia Feng,Ping Li,Qianhui Gu et al.
Chunxia Feng et al.
Objective: PD-1 inhibitors are increasingly used in advanced cancers, but reliable biomarkers for predicting treatment response remain limited. Methods: ...
Trends and Research Hotspots in Biomarkers of Sjögren's Syndrome Over the Past Two Decades: A Data-Driven Atlas Analysis [0.03%]
过去二十年干燥综合征生物标志物研究趋势和热点的 atlas 分析
Xinyan Zhang,Huan Li,Xueqing Zhou et al.
Xinyan Zhang et al.
Background: Sjögren's syndrome (SS) is a chronic, systemic inflammatory disorder primarily characterized by dry eyes and dry mouth, often involving multiple organ systems. The disease's heterogeneous clinical presentatio...
Widespread SARS-CoV-2 Transmission Despite Limited Reported Cases and Clinical Disease: Exploring the Role of Pre-Existing Humoral Immunity to SARS-CoV-2 in Eastern Sierra Leone [0.03%]
SARS-CoV-2广泛传播及其在东塞拉利昂的存在：既往存在的针对SARS-CoV-2的体液免疫的作用研究
Robert J Samuels,Nell G Bond,Ibrahim Sumah et al.
Robert J Samuels et al.
Background: Since December 2019, SARS-CoV-2 has infected over 700 million people and caused > 7 million deaths. While much of the global north was severely affected, sub-Saharan Africa was relatively spared. Possible reas...
Asperosaponin VI Alleviates Cisplatin-Induced Liver Injury Through the Nrf2/HO-1 Signaling Pathway [0.03%]
绞股蓝皂苷VI通过Nrf2/HO-1信号途径缓解顺铂致肝损伤作用研究
Han-Hua Li,Xiao-Ming Zhou,Chuan-Wei Sun et al.
Han-Hua Li et al.
Background: Cisplatin (Cis) chemotherapy-induced hepatotoxicity frequently leads to treatment interruption or dose reduction, ultimately compromising therapeutic outcomes. Asperosaponin VI (AVI), a bioactive triterpenoid ...
Autoimmune Phenomena and New-Onset Type 1 Diabetes Following SARS-CoV-2 Vaccination: A Personal Perspective [0.03%]
SARS-CoV-2疫苗接种后新发1型糖尿病的自身免疫现象——个人视角
Kimihiko Sugaya
Kimihiko Sugaya
A molecular biologist whose wife suddenly developed type I diabetes in the summer of 2022 addresses the possible risk of developing autoimmune disease from messenger RNA (mRNA) vaccination against SARS-CoV-2. This essay also provides a reco...
Clinicopathologic Characterization of Muscle Biopsy Findings in Overlap Myositis: A Single Tertiary Care Center Experience [0.03%]
重叠型肌炎肌肉活检的临床病理特征：一家三级医疗中心的经验
Sidra Fatima,Megha Uppin,Liza Rajasekhar et al.
Sidra Fatima et al.
Objective: This study aims to describe the muscle biopsy features of overlap myositis (OM) and compare them with other inflammatory myopathies. We analyzed clinical, serological findings, and histopathological patterns in...
Performance of Three Commercial Rapid Diagnostic Tests for Detection of IgM and IgG Antibodies Against SARS-CoV-2 [0.03%]
三种用于检测SARS-CoV-2 IgM和IgG抗体的商业快速诊断检测试剂盒的性能评估
Moyra Machado Portilho,Stephane Fraga de Oliveira Tosta,Maysa Pellizzaro et al.
Moyra Machado Portilho et al.
Background: Despite widespread vaccination, SARS-CoV-2 transmission continues, and serological testing remains relevant for selected diagnostic scenarios and population-based assessments of antibody responses. Rapid diagn...
Inflammatory Biomarkers as Mediators of the Effect Between High-Dose Corticosteroid Therapy and Mortality in COVID-19-Related ARDS: A Causal Mediation Analysis [0.03%]
高剂量皮质类固醇治疗COVID-19相关ARDS患者的死亡率：炎症生物标志物的因果中介分析
Katrijn Daenen,Anders Boyd,Virgil A S H Dalm et al.
Katrijn Daenen et al.
Background: Treatment guidelines for acute respiratory distress syndrome (ARDS) recommend the use of high-dose corticosteroids based on their anti-inflammatory effects, yet the efficacy of this therapeutic strategy in pat...
Inhibition of NTF4 Attenuates High Glucose-Induced Apoptosis and Inflammation in HTR-8/SVneo Cells via the PI3K/AKT Pathway [0.03%]
NTF4抑制通过PI3K/AKT信号途径缓解高糖诱导的HTR-8/SVneo细胞凋亡和炎症反应
Li Zhang,Juan Yang
Li Zhang
Objective: This study aims to investigate the role of neurotrophin-4 (NTF4) in gestational diabetes mellitus (GDM) and to elucidate the underlying mechanism by which NTF4 regulates high glucose-induced apoptosis and infla...