Carbon Monoxide Alleviates Cardiomyocyte Pyroptosis in Diabetic Cardiomyopathy by Downregulating the IL-33/ST2L Axis [0.03%]
一氧化碳通过下调IL-33/ST2L轴缓解糖尿病心肌病 cardiomyocytes 中的pyroptosis
Chunjie Jiang,Ping Zhu,Ping Yao et al.
Chunjie Jiang et al.
Objectives: This study aimed to investigate whether carbon monoxide (CO) can alleviate cardiomyocyte pyroptosis by downregulating the IL-33/ST2L axis in diabetic cardiomyopathy (DCM). ...
Development of Thymic Organoids Heterotopically to Educate and Induce T Lymphocytes [0.03%]
异位发育胸腺类器官以教育和诱导T淋巴细胞
Xiuxia Wang,Shun Yu,Yucheng Qiu et al.
Xiuxia Wang et al.
Background: Vascularized composite allotransplantation (VCA) is a potential treatment for extensive injuries that replaces defects like-with-like, however allografts are immune-rejectable. ...
Identification of Plasma Biomarkers for B7 Family Members Associated With Primary Sjögren's Syndrome [0.03%]
原发性舍格伦综合征相关B7家族成员的血浆生物标志物鉴定
Saizhe Song,Yanhong Yang,Yu Shen et al.
Saizhe Song et al.
Objectives: To evaluate the plasma levels of B7 family members (B7-H1, B7-H2, B7-H3, B7-H4, B7-H5, and B7-H6) in primary Sjögren's syndrome (pSS) patients and investigate their potential associations with disease activit...
RUNX1 Is an Independent Prognostic Marker Involved in Immune Infiltration and Therapeutic Responses in Clear Cell Renal Cell Carcinoma Patients Through Cluster Regulation With RUNX2 [0.03%]
RUNX1通过与RUNX2聚类调控参与免疫浸润和治疗反应，在透明细胞肾细胞癌患者中是一个独立的预后标志物
Jingang Jian,Jun Zhang,Hongbo Xu et al.
Jingang Jian et al.
Background: Immunomodulation is an important factor in clear cell renal cell carcinoma (ccRCC) carcinogenesis and the treatment outcome of ccRCC patients. Understanding of the roles of the immune-related Runt-related tran...
Human Umbilical Cord Mesenchymal Stem Cells Modulate Cytokine Secretion of CD4+ T Cell in Systemic Lupus Erythematosus by Inhibiting HSP90AA1 in the Glucose-Activated PI3K-AKT Pathway [0.03%]
人脐带间充质干细胞通过抑制葡萄糖活化PI3K-AKT途径中的HSP90AA1调节系统性红斑狼疮CD4+T细胞的细胞因子分泌
Lu Jin,Meng Ding,Shaoxin Cui et al.
Lu Jin et al.
Objective: Treatment with human umbilical cord mesenchymal stem cells (hUC-MSCs) attenuated the clinical manifestations of systemic lupus erythematosus (SLE). We investigated the metabolic mechanism whereby hUC-MSCs modif...
Cold Atmospheric Plasma in the Treatment of Autoimmune Diseases: Mechanisms, Applications, and Prospects [0.03%]
冷等离子体在自身免疫疾病治疗中的作用机制、应用及前景展望
Zhenyu Li,Minglong Cai,Zhu Chen
Zhenyu Li
Background: Autoimmune diseases, including rheumatoid arthritis (RA), are characterized by an aberrant immune responses that leads to chronic inflammation and tissue damage. Traditional treatments, such as immunosuppressi...
An Animal Model of Liuzijue Based on Kinematic Features Exploration: A Pilot Study Conducting in COPD [0.03%]
基于运动学特征的六字诀动物模型研究初探（开展于慢性阻塞性肺疾病模型中）
Jian Li,Xiang Ji,Kangxia Li et al.
Jian Li et al.
Background: Liuzijue is an essential nonpharmacological intervention within the comprehensive management strategies for chronic obstructive pulmonary disease (COPD) patients. However, the absence of an animal model for Li...
Clinical Features of Central Nervous System Complications Caused by the SARS-CoV-2 Omicron Variant [0.03%]
SARS-CoV-2奥密克戎变异株中枢神经系统并发症的临床特征
Tingting Li,Zhirong Deng,Qinfu Zhang et al.
Tingting Li et al.
Background: This study investigated clinical characteristics and cerebrospinal fluid (CSF) features of central nervous system (CNS) complications in adults caused by the severe acute respiratory syndrome coronavirus 2 (SA...
Urban Lifestyle and Climate-Driven Environmental Exposures: Immunological Consequences for Pediatric Respiratory Allergies [0.03%]
城市生活方式和气候驱动的环境暴露对儿童呼吸道过敏的免疫学影响
Zahra Kanannejad,Walter Robert Taylor,Milad Mohkam et al.
Zahra Kanannejad et al.
Pediatric respiratory allergic diseases, including asthma and allergic rhinitis, are increasingly recognized as significant global health concerns, with rising prevalence rates linked to environmental changes driven by urbanization and clim...
Clinical Characteristics of Patients With Respiratory Infections After Nonpharmacological Interventions for COVID-19 in China Have Ended: Using Machine Learning Approaches to Support Pathogen Prediction at Admission [0.03%]
中国结束COVID-19非药物干预后呼吸系统感染患者的临床特征：使用机器学习方法支持入院病原预测
Tian-Ning Li,Yan-Hong Liu,Kwok-Leung Yiu et al.
Tian-Ning Li et al.
Objectives: In the aftermath of the COVID-19 pandemic, China witnessed a surge in respiratory virus infections, which presented considerable challenges to primary health care systems. This study developed an interpretable...