Arbovirus-Associated Guillain-Barré Syndrome: A Systematic Review and Meta-Analysis of Clinical Characteristics, Subtypes, and Vaccine Associations [0.03%]
与虫媒病毒相关的吉兰-巴雷综合征：系统性回顾和临床特点、分型及疫苗相关性的Meta分析
Eman Taha Osman Ali,Pierre Gashema,Patrick Gad Iradukunda et al.
Eman Taha Osman Ali et al.
Background: Arboviral infections are increasingly recognized as triggers of Guillain-Barré syndrome (GBS), yet the clinical spectrum, subtype distribution, and strength of association across different arboviruses remain ...
LncRNA Mirt2 Attenuates Osteoarthritis Progression by Promoting miR-429/TBK1-Mediated Autophagy [0.03%]
长链非编码RNA Mirt2通过促进miR-429/TBK1介导的自噬来抑制骨关节炎进展
Jian-Xin Zhang,Zheng Li,Ping Yang et al.
Jian-Xin Zhang et al.
Object: Osteoarthritis (OA) is a chronic and degenerative joint disorder that is prevalent in middle-aged and older populations. While several long non-coding RNAs (lncRNAs) have been implicated in OA progression, the rol...
Thrombospondin-4 Regulates Lipopolysaccharide-Induced Apoptosis and Inflammation in Nucleus Pulposus Cells via the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway [0.03%]
血小板反应蛋白4通过磷脂酰肌醇3-激酶/蛋白质 kinase B信号通路调节脂多糖诱导的髓核细胞凋亡及炎症反应
Yang Shu,Chunhua Sun,Shi Chen
Yang Shu
Objective: This study investigated the expression profile of Thrombospondin-4 (THBS4) in intervertebral disc degeneration (IDD) and clarify its regulatory role in lipopolysaccharide (LPS)-induced apoptosis and inflammatio...
Spectral Flow Cytometry Method for Immunophenotyping Neutrophil Activation and NETs in an Acute Dust Exposure Model [0.03%]
急性粉尘暴露模型中免疫表型 neutrophil 激活和NETs的光谱流式细胞法
Logan S Dean,Maëlis J L Wahl,Pinaki Mondal et al.
Logan S Dean et al.
Background: Although the contributions of neutrophils and neutrophil extracellular trap (NET) in chronic respiratory diseases associated with environmental dust inhalation has advanced, changes in neutrophil populations a...
Association Between Systemic Immune-Inflammation Index and Sepsis-Induced Liver Injury in Adult Patients With Sepsis: A Retrospective Cohort Study [0.03%]
系统免疫炎症指数与成人脓毒症患者脓毒血症诱导肝损伤的相关性：一项回顾性队列研究
Zimeng Qin,Jiaqi Li,Yijiang Liu et al.
Zimeng Qin et al.
Background: Sepsis-induced liver injury (SILI) is a fatal complication of organ failure that currently lacks reliable biomarkers for early diagnosis and risk prediction. This study aimed to explore the link between the sy...
Immune Cells as Mediators Between Gut Microbiota and Multiple Sclerosis: Insights From Mendelian Randomization [0.03%]
肠道微生物群与多发性硬化之间的免疫细胞介导作用：来自孟德尔随机化研究的启示
Pingping Ning,Xin Mu,Xiaohui Zhang et al.
Pingping Ning et al.
Background: Multiple sclerosis (MS) is a neuroimmunological disorder marked by demyelination and neuronal damage, significantly impacting young individuals' health and quality of life. Recent studies suggest a pivotal rol...
Development and Validation of a Nomogram to Predict Respiratory Failure With Influenza [0.03%]
流感呼吸衰竭预测列线图的建立和验证
Mingzhen Zhao,Yi Li,Hongxiang Fu et al.
Mingzhen Zhao et al.
Purpose: Influenza-induced respiratory failure is a severe complication of influenza that can rapidly progress to multi-organ failure or even death due to severe impairment of pulmonary ventilation or gas exchange functio...
Dysregulation of the TLR4/MyD88/NF-κB Signaling Pathway and Pro-Inflammatory Cytokines in First-Episode Major Depressive Disorder: A Cross-Sectional Case-Control Study [0.03%]
首次发作的重大抑郁症中TLR4/MyD88/NF-κB信号通路及促炎症细胞因子的失调：横断面病例对照研究
Yaser Mohammadi,Omid Kooshkaki,Aliakbar Esmaeili et al.
Yaser Mohammadi et al.
Introduction: Inflammation is increasingly recognized as a key contributor to the development and progression of major depressive disorder (MDD). This case-control study aims to assess the expression of inflammatory pathw...
Research Progress on Anti-Inflammatory Adipokine SFRP5-Mediated Lipid Metabolism and Its Potential Role in Neural Development [0.03%]
SFRP5抗炎作用介导脂代谢及潜在神经发育功能的研究进展
Qianfang Jia,Zihan Li,Tianyi Yang et al.
Qianfang Jia et al.
Objective: To systematically review the structural features of secreted frizzled‑related protein 5 (SFRP5) and its dual regulation of canonical/non‑canonical Wnt signaling, analyze its association with metabolic disorde...
TCM-Guided Targeted Therapies Against NLRP3 Inflammasome in NAFLD [0.03%]
基于中医药理论的NLRP3炎性小体在非酒精性脂肪肝病靶向治疗中的指导作用
Yanxia Zhang
Yanxia Zhang
Background: Non-alcoholic fatty liver disease (NAFLD) is a prevalent metabolic disorder driven by inflammation, in which the NLRP3 inflammasome plays a central role. Current targeted inhibitors face challenges in patient ...