DUSP1 Attenuates Renal Injury in Diabetic Nephropathy by Modulating Ferroptosis: Evidence From Animal Experiments [0.03%]
DUSP1通过调节铁死亡来减轻糖尿病肾病中的肾脏损伤：来自动物实验的证据
Jiarong Liu,Junping Zhang,Yun Zou et al.
Jiarong Liu et al.
Objective: Emerging evidence suggests that ferroptosis contributes significantly to the progression of diabetic nephropathy (DN). This study aimed to explore the potential association between dual specificity phosphatase ...
Integrative Omics Analysis Reveals the Potential Value of CEACAM6 in Pan-Gastrointestinal Cancers [0.03%]
整合组学分析揭示CEACAM6在泛胃肠癌中的潜在价值
Liying Jin,Changjuan Tao,Zhiyong Pan et al.
Liying Jin et al.
Objective: Carcinoembryonic antigen cell adhesion molecule 6 (CEACAM6) is known as a cell adhesion receptor which could regulate proliferation and other signaling in cancer. The role of CEACAM6 in pan-gastrointestinal can...
Investigating the Role of A20 in Respiratory Syncytial Virus Immunopathogenesis in a BALB/c Mouse Model [0.03%]
A20基因敲除小鼠RSV感染模型中A20基因对RSV免疫病原作用的研究
Alireza Tahamtan,Mohammad Yasaghi,Saeed Samadizadeh et al.
Alireza Tahamtan et al.
Background: Respiratory syncytial virus (RSV) is a leading cause of acute respiratory tract infections in children and the elderly worldwide. RSV pathogenesis is largely driven by exaggerated host immune responses that re...
Kaempferitrin Attenuates Lipopolysaccharide-Induced Cardiac Dysfunction Through Suppression of the NF-κB/NLRP3 Signaling Pathway [0.03%]
卫矛素通过抑制NF-κB/NLRP3信号通路缓解脂多糖诱导的心脏功能障碍
Hongyu Kuang,Qiang Li,Min Chen et al.
Hongyu Kuang et al.
Purpose: The inflammatory activation and metabolic disorders of cardiomyocytes are essential mechanisms in sepsis-related cardiac dysfunction. Kaempferitrin (Kae), a flavonoid compound, possesses various properties includ...
Paeoniflorin Ameliorates Spinal Cord Injury by Controlling Apoptosis and Ferroptosis in H2O2-Damaged PC12 Cells [0.03%]
芍药苷通过调控H2O2损伤PC12细胞凋亡及铁死亡促进脊髓损伤修复作用研究
Zongyu Zhang,Zhijing Zhou,Peng Zhang et al.
Zongyu Zhang et al.
Background: Spinal cord injury (SCI) leads to severe neurological dysfunction. Current therapeutic strategies remain limited, with poor recovery rates. Oxidative stress and ferroptosis are key mechanisms underlying second...
The Progress of Ferroptosis of Immune Cells in the Tumor Microenvironment and Its Impact on Tumorigenesis and Development [0.03%]
肿瘤免疫细胞铁死亡进程及其对肿瘤发生发展的影响
Fenfen Zhan,Yanyan Hu,Xiang Jiang et al.
Fenfen Zhan et al.
Background: The immune cells within the tumor microenvironment (TME) play important roles in tumorigenesis. Ferroptosis is an iron-dependent form of non-apoptotic cell death characterized by the accumulation of lipid pero...
Short-Term Change in IgG Antibody Elicited by Omicron BA.5 Infection and Inhaled Ad5-nCoV Vaccine Among Healthcare Workers [0.03%]
奥密克戎BA.5感染和吸入式Ad5-nCoV疫苗诱导IgG抗体的短期变化研究：一项针对医务工作者的研究
Zhaohui Luo,Ting Zeng,Shi Zhao et al.
Zhaohui Luo et al.
Background: Little is known about the immune response induced by the SARS-CoV-2 Omicron BA.5 variants or the inhaled adenovirus vector vaccine. In this study, we investigated the short-term profile of antireceptor-binding...
MAFG Induces the Methylation of CRYAB to Promote the Activation of A1 Astrocyte After Spinal Cord Injury [0.03%]
MAFG通过促进CRYAB甲基化来诱导脊髓损伤后A1星形胶质细胞活化
Xuefei Li,Zhuang Zhu,Ying Wang et al.
Xuefei Li et al.
Purpose: To investigate the effects of MAF bZIP transcription factor G (MAFG) on the transformation of A1/A2 reactive astrocytes and the production of inflammatory factors after spinal cord injury (SCI). ...
Integrated Analysis of the Immune Infiltration Pattern and Novel Diagnostic Biomarkers in Septic Cardiomyopathy [0.03%]
脓毒症心肌病中免疫浸润模式的综合分析及新型诊断生物标志物的研究
Wei Liu,Xi Zheng,Dong Wang et al.
Wei Liu et al.
Purpose: In this study, various informatics analyses were employed to identify the hub genes associated with septic cardiomyopathy (SCM) onset and investigate their immune infiltration status. ...
Bilateral Chronic Expanding Hematomas of the Gluteus Maximus Presenting With Gluteal Muscle Contracture: A Case Report [0.03%]
慢性膨胀性臀大肌血肿伴发的臀肌挛缩症：一例报告
Xi-Qing Pan,Jin-Hui Liu,Jiang-Li Zhang et al.
Xi-Qing Pan et al.
Background: Chronic expanding hematoma is defined as a progressively enlarging soft tissue mass persisting beyond 1 month, typically resulting from prior trauma or surgical procedures. Although the condition is rare, its ...