Analgesic and Antidiarrheal Properties of Lappaconitine, Possibly Through Cyclooxygenase and µ-Opioid Receptor Interaction Pathways: In Vivo and In Silico Studies [0.03%]
延胡索甲素通过作用于环氧化酶和μ-阿片受体通路发挥镇痛和止泻的体内及分子机制研究
Shahid Shah,Arifa Akter,Salehin Sheikh et al.
Shahid Shah et al.
Background: Lappaconitine (LAP) is a diterpenoid alkaloid with strong anti-inflammatory activity. However, there is limited information on its gastroprotective effects. The present study aimed to explore the analgesic and...
Elevated Serum Lipopolysaccharides and Intrinsic Factor Autoantibodies Correlate With Macrocytic Anemia Among People With HIV [0.03%]
HIV患者巨幼细胞性贫血与血清脂多糖和内因子自身抗体升高有关
Daniel Amakye,Samuel Hammond,Osbourne Quaye et al.
Daniel Amakye et al.
Introduction: Human immunodeficiency virus (HIV) infection is associated with various comorbidities, including macrocytic anemia, though the role of the infection is unclear. HIV has been implicated in microbial transloca...
The Intersection of m6A Methylation and Immune Response in PCOS: A Bioinformatics Perspective [0.03%]
m6A甲基化与免疫反应在多囊卵巢综合征中的交集：生物信息学视角
Wenting Xu,Lingli Shi,Aifang Lu et al.
Wenting Xu et al.
Background: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder, the molecular underpinnings of which remain largely undefined. The most common methylation modification of RNA, N6-methyladenosine (m6A), pla...
Early Mortality Following Systemic Anticancer Therapy in Lung Cancer: A Bayesian Spatiotemporal Multilevel Analysis [0.03%]
肺癌全身抗肿瘤治疗后的早期死亡率：贝叶斯时空多水平分析
Getayeneh Antehunegn Tesema,Rob G Stirling,Win Wah et al.
Getayeneh Antehunegn Tesema et al.
Introduction: Despite advances in lung cancer treatment, early mortality following Systemic Anticancer Therapy (SACT) remains a major concern. Identifying patients at high risk of early mortality may inform treatment deci...
Clinical Analysis of Neonatal Influenza in the Neonatal Intensive Care Unit: A Retrospective Study [0.03%]
新生儿重症监护病房内新生儿流感的临床分析：回顾性研究
Min Zhou,Jia Chen,Jing Zhao et al.
Min Zhou et al.
Background: To describe the clinical characteristics, treatment, and outcomes of neonatal influenza. Methods: Retrospectively analyzed ...
Ginsenoside Rg3 Ameliorates Psoriasis-Like Dermatitis through Inhibition of NF-κB/NLRP3 Inflammasome Signaling and Regulating Th17/Treg Balance [0.03%]
Ginsenoside Rg3通过抑制NF-κB/NLRP3炎性小体信号及调控Th17/Treg平衡改善银屑病样皮炎
Liyun Gao,Qingge Xie,Zhaoli Zhou et al.
Liyun Gao et al.
Background: Psoriasis, characterized as a persistent cutaneous inflammatory condition driven by aberrant immunity, exhibits pathogenesis and disease course heavily influenced by sustained inflammatory activity. Ginsenosid...
Antibiotic Therapy and Factors Predicting Prolonged Hospitalization Among Children Under Three Years Diagnosed With Respiratory Syncytial Virus-Associated Lower Respiratory Infection [0.03%]
抗生素治疗和影响三岁以下呼吸道合胞病毒所致下呼吸道感染儿童住院时间延长的因素分析
Ali Alsuheel Asseri
Ali Alsuheel Asseri
Background: Respiratory syncytial virus (RSV) is a common cause of lower respiratory infections (LRIs) in infants and young children. Antibiotic overuse remains a significant concern in hospitalized children with RSV-asso...
Human Leukocyte Antigen (HLA) and Tumor Immunity: A Critical Link in Cancer Immunotherapy [0.03%]
人类白细胞抗原(HLA)与肿瘤免疫：癌症免疫治疗的关键环节
Donath Damian
Donath Damian
Background: Malignant tumors pose a serious threat to human health and survival, with profound economic consequences worldwide. Human leukocyte antigens (HLAs), encoded by the human major histocompatibility complex, repre...
Kaempferol Attenuates Oxidative Stress-Induced Injury in Gastric Mucosal Cells by Activating Nrf2/GPX4 Axis to Inhibit Ferroptosis [0.03%]
山柰酚通过激活Nrf2/GPX4信号轴抑制铁死亡从而减轻氧化应激所致胃黏膜细胞损伤
Chao Luo,Jing Yan,Yun Shen et al.
Chao Luo et al.
Objective: This study explores how Kaempferol (KAE) protects against oxidative stress-induced damage by suppressing ferroptosis via the Nrf2/GPX4 axis in gastric mucosal cells. ...
The Factors Influencing the Efficacy of Pregabalin Combined With Lidocaine in the Treatment of Postherpetic Neuralgia Patients: An Analysis [0.03%]
普瑞巴林联合利多卡因治疗带状疱疹后神经痛疗效的影响因素分析
Xinkai Wang,Weiliang Cong,Jian Jin et al.
Xinkai Wang et al.
Objective: This study aims to analyze the primary factors influencing the therapeutic effect of pregabalin combined with lidocaine in patients with post-herpetic neuralgia (PHN). ...