Effect of MP-AzeFlu compared to monotherapy on COX-2, PGE2 , and EP2 gene expression in upper airway mucosa [0.03%]
与单药治疗相比，MP-AzeFlu对上呼吸道黏膜COX-2、PGE2和EP2基因表达的影响
Sonia Vicens-Artes,Jordi Roca-Ferrer,Valeria Tubita et al.
Sonia Vicens-Artes et al.
MP-AzeFlu (intranasal fluticasone and azelastine) has been widely studied and has demonstrated efficacy in Allergic rhinitis with a superior effect compared to these drugs administered individually; however, the mechanism by which MP-AzeFlu...
Laurent Hany,Marc-Olivier Turmel,Corinne Barat et al.
Laurent Hany et al.
Introduction: HIV-1 eradication is hindered by the presence of inducible long-lived reservoirs of latently infected cells which rapidly disseminate viral particles upon treatment interruption. Eliminating these reservoirs...
Circ_0138960 contributes to lipopolysaccharide-induced periodontal ligament cell dysfunction [0.03%]
环状RNA Circ_0138960参与脂多糖诱导的牙周韧带细胞功能障碍
Shuangshuang Li,Huilin Xu,Yuanyuan Li et al.
Shuangshuang Li et al.
Background: Periodontitis is a common oral inflammatory disease, and lipopolysaccharide (LPS) is a key risk factor in periodontitis pathology. Here, we used LPS-induced periodontal ligament cells (PDLCs) to explore the mo...
Emergence of SARS-CoV-2 Omicron variant and strategies for tackling the infection [0.03%]
SARS-CoV-2奥密克戎变异株的出现及防控策略
Yan Wu,Yiyin Long,Feng Wang et al.
Yan Wu et al.
Introduction: Nowadays, emerging SARS-CoV-2 Omicron, the novel highly mutated VOC, has quickly spread as the dominant variant in over 190 countries worldwide through the first part of 2022, which is influencing the infect...
Sara Molaaghaee-Rouzbahani,Nastaran Asri,Somayeh Jahani-Sherafat et al.
Sara Molaaghaee-Rouzbahani et al.
Background: So far, limited studies have focused on the role of Macrophages (MQs) in the development or progression of celiac disease (CD). Researchers believe that increasing knowledge about the function of MQs in inflam...
Diosgenin protects retinal pigment epithelial cells from inflammatory damage and oxidative stress induced by high glucose by activating AMPK/Nrf2/HO-1 pathway [0.03%]
Diosgenin通过激活AMPK/Nrf2/HO-1通路保护视网膜色素上皮细胞免受高血糖诱导的炎症损伤和氧化应激
Yang Hao,Xuefeng Gao
Yang Hao
Introduction: Diosgenin is a natural steroidal compound with reported antidiabetic and many other protective properties. This study aimed to explore the protective effect of diosgenin on high-glucose (HG)-induced retinal ...
Katharina Streich,Margarethe Klein,Anja Siebert et al.
Katharina Streich et al.
Introduction: Obesity increases the risk of several diseases, such as type 2 diabetes mellitus and cardiovascular disease. Obesity also affects the immune system. When dietary lipids are transported via the lymphatics, th...
TMEM173 rs7447927 genetic polymorphism and susceptibility to severe enterovirus 71 infection in Chinese children [0.03%]
跨膜蛋白173基因多态性与儿童重症肠道病毒71型感染易感性的关系研究
Jie Song,Yedan Liu,Ya Guo et al.
Jie Song et al.
Introduction: This study was designed to explore the association between the TMEM173 polymorphism (rs7447927) and the severity of enterovirus 71 (EV71) infection among Chinese children. ...
A decreased number of circulating regulatory T cells is associated with adverse pregnancy outcomes in patients with systemic lupus erythematosus [0.03%]
系统性红斑狼疮患者循环中的调节T细胞数量减少与不良妊娠结局相关
He-Tong Li,Sheng-Xiao Zhang,Jia-Qi Zhang et al.
He-Tong Li et al.
Objective: As an autoimmune disease affecting women of reproductive age, systemic lupus erythematosus (SLE) is linked to adverse fetal and maternal outcomes. However, the status of peripheral lymphocytes in SLE patients w...
The role of the NLRP3 inflammasome in chronic inflammation in asthma and chronic obstructive pulmonary disease [0.03%]
NLRP3炎性小体在哮喘和慢性阻塞性肺疾病中的慢性炎症中的作用
Yaxin Wu,Xin Di,Min Zhao et al.
Yaxin Wu et al.
Asthma and chronic obstructive pulmonary disease (COPD) are lung diseases characterized by airflow limitation and chronic inflammation. More and more studies have shown that the occurrence and development of asthma and COPD are related to a...