Modelling c-Abl Signalling in Activated Neutrophils: the Anti-inflammatory Effect of Seliciclib [0.03%]
模拟Seliciclib在活化中性粒细胞c-Abl信号转导中的抗炎效应
Robert C Jackson,Tomas Radivoyevitch
Robert C Jackson
When mammalian tissues are infected by bacteria or fungi, inflammatory cytokines are released that cause circulating neutrophils to invade the infected tissue. The cytosolic tyrosine kinase, c-Abl, in these tissue neutrophils is activated b...
Identification of a novel deletion mutant strain in Saccharomyces cerevisiae that results in a microsatellite instability phenotype [0.03%]
在酿酒酵母中鉴定出一种新型的缺失突变株导致微卫星不稳定的表型
Hanlee P Ji,Shannon Morales,Katrina Welch et al.
Hanlee P Ji et al.
The DNA mismatch repair (MMR) pathway corrects specific types of DNA replication errors that affect microsatellites and thus is critical for maintaining genomic integrity. The genes of the MMR pathway are highly conserved across different o...