Analysis of foothold selection during locomotion using terrain reconstruction [0.03%]
基于地形重构的行走过程中落足点选择分析方法研究
Karl S Muller,Kathryn Bonnen,Stephanie M Shields et al.
Karl S Muller et al.
Relatively little is known about the way vision is used to guide locomotion in the natural world. What visual features are used to choose paths in natural complex terrain? To answer this question, we measured eye and body movements while pa...
Cross-species alignment along the chronological axis reveals evolutionary effect on structural development of the human brain [0.03%]
跨时间轴的跨物种对齐揭示了人类大脑结构发展的进化效应
Yue Li,Qinyao Sun,Shunli Zhu et al.
Yue Li et al.
Disentangling the evolution mysteries of the human brain has always been an imperative endeavor in neuroscience. Although many previous comparative studies revealed genetic, brain structural and connectivity distinctness between human and o...
Cody A Freas,Ajay Narenda,Trevor Murray et al.
Cody A Freas et al.
For the first time in any animal, we show that nocturnal bull ants use the exceedingly dim polarisation pattern produced by the moon for overnight navigation. The sun or moon can provide directional information via their position; however, ...
Decoding contextual influences on auditory perception from primary auditory cortex [0.03%]
听觉皮层的上下文效应解码
Bernhard Englitz,Sahar Akram,Mounya Elhilali et al.
Bernhard Englitz et al.
Perception can be highly dependent on stimulus context, but whether and how sensory areas encode the context remains uncertain. We used an ambiguous auditory stimulus - a tritone pair - to investigate the neural activity associated with a p...
Arthur D Kuo
Arthur D Kuo
A mathematical model can predict the path walkers take through a rugged landscape, including the tendency of people to avoid paths that are too steep, even if it means going farther. ...
Editorial
eLife. 2024 Dec 9:13:e104965. DOI:10.7554/eLife.104965 2024
Unified bursting strategies in ectopic and endogenous even-skipped expression patterns [0.03%]
异位和内源even-skipped表达模式中的统一爆发策略
Augusto Berrocal,Nicholas C Lammers,Hernan G Garcia et al.
Augusto Berrocal et al.
Transcription often occurs in bursts as gene promoters switch stochastically between active and inactive states. Enhancers can dictate transcriptional activity in animal development through the modulation of burst frequency, duration, or am...
Pharmacologically inducing regenerative cardiac cells by small molecule drugs [0.03%]
小分子药物诱导心脏细胞再生的药理学研究
Wei Zhou,Kezhang He,Chiyin Wang et al.
Wei Zhou et al.
Adult mammals, unlike some lower organisms, lack the ability to regenerate damaged hearts through cardiomyocytes (CMs) dedifferentiation into cells with regenerative capacity. Developing conditions to induce such naturally unavailable cells...
The identification of extensive samples of motor units in human muscles reveals diverse effects of neuromodulatory inputs on the rate coding [0.03%]
人类肌肉广泛取样的运动单元的识别揭示了神经调制输入对速率编码的各种影响
Simon Avrillon,François Hug,Roger M Enoka et al.
Simon Avrillon et al.
Movements are performed by motoneurons transforming synaptic inputs into an activation signal that controls muscle force. The control signal emerges from interactions between ionotropic and neuromodulatory inputs to motoneurons. Critically,...
The cation channel mechanisms of subthreshold inward depolarizing currents in the mice VTA dopaminergic neurons and their roles in the chronic-stress-induced depression-like behavior [0.03%]
小鼠中脑多巴胺能神经元阈下去极化内向电流的阳离子通道机制及其在慢性压力源所致抑郁样行为中的作用研究
Jing Wang,Min Su,Dongmei Zhang et al.
Jing Wang et al.
The slow-intrinsic-pacemaker dopaminergic (DA) neurons originating in the ventral tegmental area (VTA) are implicated in various mood- and emotion-related disorders, such as anxiety, fear, stress and depression. Abnormal activity of project...
Maternal obesity may disrupt offspring metabolism by inducing oocyte genome hyper-methylation via increased DNMTs [0.03%]
母体肥胖通过增加DNMTs诱导卵子基因组高甲基化从而可能干扰后代代谢
Shuo Chao,Jun Lu,Li-Jun Li et al.
Shuo Chao et al.
Maternal obesity has deleterious effects on the process of establishing oocyte DNA methylation; yet the underlying mechanisms remain unclear. Here, we found that maternal obesity disrupted the genomic methylation of oocytes using a high-fat...