Ayumi Mizuno,Malgorzata Lagisz,Pietro Pollo et al.
Ayumi Mizuno et al.
Eyespot patterns have evolved in many prey species. These patterns were traditionally explained by the eye mimicry hypothesis, which proposes that eyespots resembling vertebrate eyes function as predator avoidance. However, it is possible t...
Meta-Analysis
eLife. 2024 Dec 12:13:RP96338. DOI:10.7554/eLife.96338 2024
Evaluation of clonal hematopoiesis and mosaic loss of Y chromosome in cardiovascular risk: An analysis in prospective studies [0.03%]
克隆性血细胞增多和Y染色体嵌合型丢失与心血管风险评估：前瞻性研究的分析结果
Sami Fawaz,Severine Marti,Melody Dufossee et al.
Sami Fawaz et al.
Background: Clonal hematopoiesis of indeterminate potential (CHIP) was initially linked to a twofold increase in atherothrombotic events. However, recent investigations have revealed a more nuanced picture, suggesting tha...
A multiplexed, single-cell sequencing screen identifies compounds that increase neurogenic reprogramming of murine Muller glia [0.03%]
一种多路复用的单细胞测序筛选技术，鉴定出了能够促进小鼠Müller胶质细胞重编程为神经元的化合物
Amy Tresenrider,Marcus Hooper,Levi Todd et al.
Amy Tresenrider et al.
Retinal degeneration in mammals causes permanent loss of vision, due to an inability to regenerate naturally. Some non-mammalian vertebrates show robust regeneration, via Muller glia (MG). We have recently made significant progress in stimu...
The evolutionary history of the ancient weevil family Belidae (Coleoptera: Curculionoidea) reveals the marks of Gondwana breakup and major floristic turnovers, including the rise of angiosperms [0.03%]
古大陆漂移及重大植物群转变 包括被子植物崛起等事件驱动的甲虫新科Ancient Weevil Family Belidae的演化历史研究
Xuankun Li,Adriana E Marvaldi,Rolf G Oberprieler et al.
Xuankun Li et al.
The rise of angiosperms to ecological dominance and the breakup of Gondwana during the Mesozoic marked major transitions in the evolutionary history of insect-plant interactions. To elucidate how contemporary trophic interactions were influ...
Marcks and Marcks-like 1 proteins promote spinal cord development and regeneration in Xenopus [0.03%]
非洲爪蟾脊髓发育和再生依赖Marcks和Marcks-like 1蛋白
Mohamed El Amri,Abhay Pandit,Gerhard Schlosser
Mohamed El Amri
Marcks and Marcksl1 are abundant proteins that shuttle between the cytoplasm and membrane to modulate multiple cellular processes, including cytoskeletal dynamics, proliferation, and secretion. Here, we performed loss- and gain-of-function ...
Pharyngeal neuronal mechanisms governing sour taste perception in Drosophila melanogaster [0.03%]
拟南芥中调控酸味感知的咽部神经机制
Bhanu Shrestha,Jiun Sang,Suman Rimal et al.
Bhanu Shrestha et al.
Sour taste, which is elicited by low pH, may serve to help animals distinguish appetitive from potentially harmful food sources. In all species studied to date, the attractiveness of oral acids is contingent on concentration. Many carboxyli...
Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis [0.03%]
疟原虫需要一种分歧血红素氧化酶用于叶绿体基因表达和生物合成
Amanda Mixon Blackwell,Yasaman Jami-Alahmadi,Armiyaw S Nasamu et al.
Amanda Mixon Blackwell et al.
Malaria parasites have evolved unusual metabolic adaptations that specialize them for growth within heme-rich human erythrocytes. During blood-stage infection, Plasmodium falciparum parasites internalize and digest abundant host hemoglobin ...
Associative plasticity of granule cell inputs to cerebellar Purkinje cells [0.03%]
小脑颗粒细胞输入到浦肯野细胞的关联可塑性
Rossella Conti,Céline Auger
Rossella Conti
Granule cells of the cerebellum make up to 175,000 excitatory synapses on a single Purkinje cell, encoding the wide variety of information from the mossy fibre inputs into the cerebellar cortex. The granule cell axon is made of an ascending...
Emergence of power-law distributions in protein-protein interaction networks through study bias [0.03%]
文献偏倚导致的蛋白质-蛋白质相互作用网络中幂律分布的出现
David B Blumenthal,Marta Lucchetta,Linda Kleist et al.
David B Blumenthal et al.
Degree distributions in protein-protein interaction (PPI) networks are believed to follow a power law (PL). However, technical and study bias affect the experimental procedures for detecting PPIs. For instance, cancer-associated proteins ha...
Hypersensitive intercellular responses of endometrial stromal cells drive invasion in Endometriosis [0.03%]
子宫内膜异位症中内膜间质细胞的高敏细胞反应驱动浸润发生
Chun-Wei Chen,Jeffery B Chavez,Ritikaa Kumar et al.
Chun-Wei Chen et al.
Endometriosis is a debilitating disease affecting 190 million women worldwide and the greatest single contributor to infertility. The most broadly accepted etiology is that uterine endometrial cells retrogradely enter the peritoneum during ...