Xiaomeng Zhang,Rachel Xu,Dmitry Zorin et al.
Xiaomeng Zhang et al.
Objectives: Chimeric antigen receptor (CAR) T cell therapies have transformed the treatment of B cell malignancies and show promise in other diseases, including autoimmune disorders and cardiac injury. However, broader ap...
High-dimensional flow cytometry reveals lymphocyte subset populations predictive of chronic lung allograft dysfunction [0.03%]
高维流式细胞术可揭示预测慢性肺移植功能障碍的淋巴细胞亚群
Rohia Farighi,Steven Hiho,Thomas Ashhurst et al.
Rohia Farighi et al.
Objectives: Despite cellular and antibody-mediated rejection being clinically relevant drivers of chronic lung allograft dysfunction (CLAD), there are few studies describing the T- and B-cell dynamics inherent to such all...
IgG promotes TNF-α induced osteoclastogenesis by upregulating the expression of TNFR1 and the NF-κB signalling pathway [0.03%]
IgG通过上调TNFR1及NF-κB信号通路表达促进TNF-α诱导的破骨细胞生成
Haifeng Yin,Yao Teng,Guo-Min Deng
Haifeng Yin
Objectives: Tumor necrosis factor-α (TNF-α) plays a pivotal role in bone damage associated with inflammatory arthritis such as rheumatoid arthritis (RA). Both systemic lupus erythematosus (SLE) and rheumatoid arthritis ...
Elucidating novel immune profiles for predicting infection in high-risk cohorts: a pilot study in patients with relapsed and refractory chronic lymphocytic leukaemia [0.03%]
阐明新型免疫谱型以预测高危患者感染的前瞻性研究：复发和难治性慢性淋巴细胞白血病患者的初步研究报告
Lewis J Williams,Connie Sn Li-Wai-Suen,Alex L Garnham et al.
Lewis J Williams et al.
Objectives: Chronic lymphocytic leukaemia (CLL) patients are at increased risk for infection, with the risk even higher for relapsed and refractory patients. Clinical assessment of infection risk is increasingly challengi...
SIRT7 ameliorates Th17/Treg imbalance by desuccinylation of STAT3 to improve immune thrombocytopenia [0.03%]
脱琥珀酰化STAT3改善SIRT7介导的Th17/Treg平衡以治疗免疫性血小板减少症
Jiao Ge,Xiaoyan Zhang,Fajuan Tang et al.
Jiao Ge et al.
Objectives: The imbalance of Th17/Treg cells represents a key pathogenic mechanism in immune thrombocytopenia (ITP); however, the underlying regulatory mechanisms remain poorly understood. Dysregulated succinylation has b...
Engineered iPSC-derived natural killer cells: recent innovations in translational innate anti-cancer immunotherapy [0.03%]
工程化的诱导多能干细胞来源的自然杀伤细胞：转化型先天性抗肿瘤免疫治疗的最新创新
Jane Sun,Melissa Elliott,Fernando Souza-Fonseca-Guimaraes
Jane Sun
Natural killer (NK) cells are increasingly recognised as potent tumoricidal agents that can be utilised for cancer immunotherapy. Their innate cytotoxicity against tumor cells, and reduced risk of causing transplantation or toxicity issues ...
Erratum: Data standards for single-cell RNA-sequencing of paediatric cancer [0.03%]
更正：儿科癌症单细胞RNA测序数据标准
[This corrects the article DOI: 10.1002/cti2.70033.]. © 2025 The Author(s). Clinical & Translational Immunology published by John Wiley & Sons Australia...
Published Erratum
Clinical & translational immunology. 2025 Jul 10;14(7):e70044. DOI:10.1002/cti2.70044 2025
The role of immunochemotherapy maintenance in metastatic nasopharyngeal carcinoma: insights from a cohort study in an endemic region [0.03%]
免疫化疗维持治疗在转移性鼻咽癌中的作用：一个地方病区域队列研究的启示
Zhuoying Luo,Yue Xia,Yuping Zhao et al.
Zhuoying Luo et al.
Objectives: Metastatic nasopharyngeal carcinoma (mNPC) following palliative chemotherapy has high incidence and mortality rates. While maintenance therapy shows promising potential, the optimal strategy remains undefined....
Cellular hierarchy for understanding heterogeneity of acute myeloid leukaemia with t(8;21)/RUNX1-RUNX1T1 [0.03%]
阐明t(8;21)/RUNX1-RUNX1T1急性髓系白血病异质性的细胞层级结构
Yibo Wu,Xiaolin Yuan,Xiaoyu Lai et al.
Yibo Wu et al.
Objectives: Differentiation hierarchies in myeloid malignancies influence therapeutic response and prognosis. Acute myeloid leukaemia (AML) with t(8;21) is one of the most recurrent genetic subtypes of AML and is consider...
Long-term immune changes after COVID-19 and the effect of BCG vaccination and latent infections on disease severity [0.03%]
COVID-19后的长期免疫变化以及卡介苗接种和潜伏感染对疾病严重程度的影响
Kamila Bendíčková,Ioanna Papatheodorou,Gabriela Blažková et al.
Kamila Bendíčková et al.
Objectives: Several years after the COVID-19 pandemic, the impact of SARS-CoV-2 on immunity and the potential protective role of Bacillus Calmette-Guérin (BCG) vaccination through trained immunity remain a subject of inv...