Follow-up study of vonoprazan maintenance therapy for reflux esophagitis: A 96-week evaluation in patients with PPI-refractory disease [0.03%]
伏诺拉赞维持治疗反流性食管炎复发的随访研究:PPI难治性患者的96周评估
Hideki Mizuno,Shingo Inagaki,Kazutoshi Yamada et al.
Hideki Mizuno et al.
Vonoprazan is a potassium-competitive acid blocker that provides more potent and sustained acid suppression than conventional proton pump inhibitors (PPIs). Vonoprazan may serve a role in the long-term management of gastroesophageal reflux ...
Metabolomic profiling reveals amino acid dysregulation in congenital heart disease: Arginine-induced embryonic malformations and pathogenic insights [0.03%]
代谢组学特征分析揭示了先天性心脏病中的氨基酸失调:精氨酸致胚胎畸形及其病理机制
Zhen Li,Can Cui,Jinping Li et al.
Zhen Li et al.
Congenital heart disease (CHD) is the most common form of malformation seen in China. In most cases, its pathogenesis is unclear. The present study aimed to identify the differential metabolites and novel screening markers to discover the p...
Real-world effectiveness and safety of cefiderocol in critically ill patients with MDR Gram-negative infections: Results from a retrospective study [0.03%]
头孢迪洛治疗多药耐药革兰阴性菌感染重症患者的真实世界疗效和安全性:一项回顾性研究的结果
Andrea Marino,Emmanuele Venanzi Rullo,Ylenia Russotto et al.
Andrea Marino et al.
The increasing prevalence of multidrug-resistant (MDR) Gram-negative bacteria, particularly Acinetobacter baumannii (A. baumannii), represents a major clinical challenge, especially in critically ill patients. Cefiderocol, a siderophore cep...
Anti-neuroinflammatory potential of porcine liver decomposition products in improving behavioral abnormalities: Effects on formalin- and LPS-induced inflammation [0.03%]
猪肝分解产物抗神经炎症的潜力可改善行为异常:甲醛和LPS诱导的炎症的影响
Ikuya Sato,Tomoji Maeda,So Katsuyama et al.
Ikuya Sato et al.
Porcine liver decomposition product (PLDP) is a functional food that enhances delayed memory recall and frontal lobe function in humans and exerts antidepressant and anxiolytic effects. In the present study, the previously unexplored anti-i...
Analysis of cell turnover in the macula densa through the normal aging process [0.03%]
正常老化过程中致密斑细胞更新的分析研究论文
Marta Ortega-Martínez,Yareth Gopar-Cuevas,Karol García-Aguilar et al.
Marta Ortega-Martínez et al.
The kidney undergoes changes during the lifespan of an individual, resulting in increased susceptibility to renal diseases in the elderly. The macula densa (MD) controls basic kidney functions, which deteriorate with aging. The present stud...
Efficacy and safety of catheter ablation with vein of Marshall ethanol infusion in patients with persistent AF and HFrEF [0.03%]
Marshall静脉乙醇注射在持续性房颤和HFrEF患者中的消融效果及安全性研究
Shilin Cheng,Jie Yin,Xinran Li et al.
Shilin Cheng et al.
Atrial fibrillation (AF) is a common arrhythmia that usually coexists with heart failure (HF). However, research into the efficacy and safety of catheter ablation with vein of Marshall ethanol infusion (VOM-EI) in patients with persistent A...
Molecular mechanisms underlying the inhibition of cell migration and invasion in endometriosis: Advances in pharmacological research (Review) [0.03%]
内异症细胞迁移和侵袭抑制的分子机制:药理学研究进展(综述)
Ni Wei,Haibin Guan,Yanfen Zhang et al.
Ni Wei et al.
Endometriosis (EMS) is a prevalent gynecological disease afflicting reproductive-age women, characterized by the presence of endometrial tissue outside the uterus. The clinical manifestations of this condition include pelvic pain, dyspareun...
Effects of aged garlic extract may differ between normal cells and cancer cells [0.03%]
老化蒜提取物对正常细胞和癌细胞的作用可能不同
Koji Harada,Tarannum Ferdous,Keisuke Kawasaki et al.
Koji Harada et al.
Aged garlic extract (AGE) is one of the widely used garlic-based products that are extensively studied and are commercially available. However, there are no reports that compare the effects of AGE on normal cells and oral cancer cells. The ...
Combined serum IFN-γ and IL-22 levels as predictive biomarkers for hepatocellular carcinoma risk: A clinical investigation [0.03%]
结合测定干扰素γ和白细胞介素22的血清水平作为肝癌风险预测标志物的临床研究
Hui Huang,Xueying Sun,Qiqi Zhang et al.
Hui Huang et al.
Hepatocellular carcinoma (HCC) is predominantly diagnosed at advanced stages due to a lack of reliable biomarkers for early detection. Consequently, identifying predictive biomarkers for HCC development in patients with chronic liver diseas...
Spectrum of PAH gene variants in Jordanian patients with phenylalanine hydroxylase deficiency [0.03%]
约旦患者苯丙氨酸羟化酶缺乏的PAH基因变异谱型分析
Rajaa Fathallah,Khadeeja Al-Rashed,Alaa Arafat et al.
Rajaa Fathallah et al.
Phenylketonuria (PKU) is an autosomal recessive metabolic disorder caused by pathogenic variants in the phenylalanine hydroxylase (PAH) gene. PKU is considered as one of the most common autosomal recessive diseases in Jordan; however, the s...