Succinate dehydrogenase-related PPGL: Clinical and Genetic Insights from Indian Study [0.03%]
来自印度的研究：与琥珀酸脱氢酶相关的PPGL的临床和遗传见解
Ketki Sunil Ambulkar,Anima Sharma,Vijaya Sarathi et al.
Ketki Sunil Ambulkar et al.
Objective: Data on Succinate dehydrogenase-related pheochromocytoma and paraganglioma (SDHx PPGL) in India is limited. We describe the clinical and genetic characteristics of SDHx PPGL from a single center in western Indi...
Shared Molecular Mechanisms Between Type 2 Diabetes and Thyroid Cancer: Integrated Bioinformatics Insights for Prognostic Biomarker Discovery [0.03%]
2型糖尿病与甲状腺癌之间的共享分子机制：综合生物信息学见解用于预后生物标志物发现
Jiahui Qi,Chuanzhi Chen,Feng Zhu et al.
Jiahui Qi et al.
Background: Thyroid cancer (TC) is a prevalent endocrine malignancy with rising global incidence, particularly among women. Emerging evidence suggests a significant association between type 2 diabetes mellitus (T2D) and T...
Enhancing Transition Care for adolescents and young adults with adrenal insufficiency in the Netherlands: A Holistic Model for Improved Patient Outcomes [0.03%]
荷兰青少年和青年人肾上腺功能不全过渡护理的增强：改善患者预后的整体模型
H L Claahsen-van der Grinten,K Davidse,Kma Dreijerink et al.
H L Claahsen-van der Grinten et al.
Transition from paediatric to adult healthcare presents unique challenges for adolescents with chronic conditions such as adrenal insufficiency (AI). This process requires careful coordination to ensure continuity of care and support as you...
Trend in Body Mass Index During Childhood in 460 Girls with Idiopathic Central Precocious Puberty [0.03%]
460例中枢性特发性性早熟女童BMI动态变化趋势分析
A Vicinanza,O Oli Atomssa,A Nebbioso et al.
A Vicinanza et al.
Objective: A secular trend toward earlier puberty onset in girls has been widely documented, with childhood overweight proposed as a contributing risk factor. This study aims to characterize body mass index (BMI) standard...
tsRNA-25172 Inhibits Aldosterone Secretion in Aldosterone-Producing Adenoma [0.03%]
TSRNA-25172通过靶向醛固酮产生腺瘤中的CACNA1D基因抑制醛固酮分泌
Qiwei Fan,Liqing Liu,Zhihua Jiang et al.
Qiwei Fan et al.
The pathophysiology of aldosterone-producing adenomas (APAs) is characterized by aldosterone hypersecretion. Transfer RNA-derived small RNAs (tsRNAs) are novel non-coding RNAs, which are involved in multiple biological processes. However, t...
Reduced Serum Sestrin 2 Levels in Hashimoto's Disease: A Cross-Sectional Study on Its Potential Pathophysiological and Diagnostic Role [0.03%]
桥本病患者血清Sestrin 2水平降低：横断面研究及其潜在病理生理和诊断作用
Merve Ates,Mesut Ates,Murat Alisik et al.
Merve Ates et al.
Objective: Expression of mammalian target of rapamycin (mTOR), which plays a key role in coordinating the balance between cell growth and autophagy, is elevated in thyroid tissues of patients with Hashimoto's disease. Ses...
Relationship between Meteorin-like and Type 2 diabetes mellitus: An update Meta-analysis [0.03%]
气象素类似物与2型糖尿病关系的更新型meta分析研究
Jing Xie,Yanhua Jiang,Jiayi Yao et al.
Jing Xie et al.
Background: Meteorin-like protein (Metrnl) is considered as a novel adipokine, which plays an important role in the occurrence and development of Type 2 diabetes mellitus (T2DM). In previous meta-analysis, no significant ...
Loss of MBD2 is associated with tumor growth in small intestinal neuroendocrine tumors [0.03%]
MBD2丢失与小肠神经内分泌肿瘤生长相关性研究
Elham Barazeghi,Samuel Backman,Per Hellman et al.
Elham Barazeghi et al.
Small intestinal neuroendocrine tumors (SI-NETs) represent the most frequent neoplasms of the small intestine, with loss of chromosome 18 as the most common genetic aberration. To date, no highly frequently mutated genes have been identifie...
Leptin and Leptin Resistance in Obesity: Current Evidence, Mechanisms and Future Directions [0.03%]
肥胖中的瘦素和瘦素抵抗：现有证据、机制及未来发展方向
Wenjing Hu,Huijuan Zhu,Fengying Gong
Wenjing Hu
Leptin, a key adipokine regulating energy homeostasis, has been extensively studied for its potential in the management of obesity. However, its therapeutic efficacy is often limited due to leptin resistance. This review synthesizes animal ...
The Association between Sleep Quality and Cognitive Function in Patients with Non-Functioning Pituitary Adenoma [0.03%]
非功能性垂体腺瘤患者睡眠质量与认知功能的相关性研究
M Brown,I L Ross,W Nkoana et al.
M Brown et al.
Background: Cortisol and growth hormone are important for sleep regulation and cognition. Sleep is critical for cognitive functioning, and memory consolidation. Patients with pituitary disease experience hormonal dysregul...