Gut-protective metabolic phenotype for diarrhoeal remission caused by an environmental probiotic thermophile [0.03%]
由环境益生芽孢杆菌介导的腹泻缓解型肠道保护代谢表型
Hirokuni Miyamoto,Hideyuki Takahashi,Wataru Suda et al.
Hirokuni Miyamoto et al.
Background: Controlling diarrhoea in humans and livestock is a global challenge with diverse aetiologies. However, the dynamics of the microbiome for diarrhoeal remission are not sufficiently understood, and effective int...
Microbially derived glutathione from Eubacterium rectale alleviates oxidative stress and promotes intestinal epithelial recovery [0.03%]
肠道细菌Eubacterium rectale来源的微生物谷胱甘肽缓解氧化应激并促进肠上皮细胞恢复
Tanner G Richie,Hallie Wiechman,Brooke Vogt et al.
Tanner G Richie et al.
Background: Certain microbes inhabiting the gut have been implicated in maintaining gut homeostasis and promoting gut damage repair. Lachnospiraceae members were highly detected in dysbiotic IL-10 KO mice that displayed s...
Tim Van Den Bossche,Lucia Grenga,Gelio Alves et al.
Tim Van Den Bossche et al.
The Metaproteomics Initiative was officially launched in 2021 to strengthen collaboration, promote knowledge exchange, and support and lead standardization efforts within the growing metaproteomics community. Over the past 5 years, the Init...
The need for standardization and improved open (meta)data practices in metaproteomics [0.03%]
metadata实践的需求促进代谢蛋白质组学的发展
Tim Van Den Bossche,Maximilian Wolf,Jean Armengaud et al.
Tim Van Den Bossche et al.
Metaproteomics enables functional insight into microbial communities by identifying and quantifying proteins in complex samples. Yet, heterogeneous analytical workflows and the lack of standardization across experimental and bioinformatics ...
Rhizobacterial functional assemblies modulate accumulation of phthalates in choysum (Brassica parachinensis L.) [0.03%]
芽胞菌功能性集合体调节对椰菜茎基部酞酸酯的累积作用
Dan-Yang Cao,Rui-Ting Wu,Huan Du et al.
Dan-Yang Cao et al.
Background: Rhizomicrobiomes exhibit dynamic adaptability in their structural and functional compositions in response to environmental stressors, playing pivotal roles in modulating host plant tolerance and growth. Nevert...
Environmental reservoirs and transmission pathways of antimicrobial resistance across the pork production continuum [0.03%]
猪肉生产链中抗菌药物耐药性的环境储存库及传播途径
Yuting Zhai,Yejin Kim,Ga-Hee Ban et al.
Yuting Zhai et al.
Background: Antimicrobial resistance (AMR) is a major One Health challenge linking human, animal, and environmental health, yet the contribution of food production environments to resistance transmission remains poorly un...
Cesarean section-induced changes in the gut microbiota facilitate metabolic disease in high-fat diet-induced obese mice [0.03%]
剖宫产引起的肠道菌群变化可促进高脂饮食诱导的肥胖小鼠代谢疾病的发展
Line Fisker Zachariassen,Frederikke Uldall Fløe Mortensen,Caroline Märta Junker Mentzel et al.
Line Fisker Zachariassen et al.
Background: The global rate of cesarean section (CS) births is increasing. Growing evidence suggests that CS birth may alter the gut microbiota (i.e., dysbiosis) and increase the risk of immune and metabolic disorders, al...
SEVA: structural and evolutionary feature integration for predicting virulence factors and antibiotic resistance genes [0.03%]
SEVA:用于预测毒力因子和抗生素抗性基因的结构及进化特征集成
Kaiqi Li,Xin Peng,Xiuwei Qian et al.
Kaiqi Li et al.
Background: Infectious diseases continue to pose unprecedented challenges to public health and the global economy. Virulence factors (VFs) enable pathogens to adhere, reproduce, and cause damage to host cells, while antib...
Invertebrates gut viromes mediate microbial adaptation to pharmaceutical diversity under warming [0.03%]
温带下无脊椎动物肠道噬菌体群介导微生物对药物多样性的适应性响应
Ya-Ning Wang,Jin-Ting Zheng,Xue-Peng Chen et al.
Ya-Ning Wang et al.
Background: Pharmaceutical pollution is an emerging environmental concern that can disrupt microbial communities and ecological processes, while climate warming adds further stress with broad ecological consequences. Soil...
Inulin alleviates vascular cognitive impairment by restoring prefrontal GABAergic function via microbiota-SCFA-GPR41/43 axis [0.03%]
低聚果糖通过重塑肠道菌群恢复依赖的短链脂肪酸G蛋白偶联受体信号通路改善血管性认知障碍中的前额叶抑制功能失调
Zhiying Zou,Junxiu Xi,Juan Li et al.
Zhiying Zou et al.
Background: Vascular cognitive impairment (VCI) impairs medial prefrontal cortex (mPFC) function, a cognitive hub reliant on intact GABAergic transmission. Although prebiotics may counteract VCI by remodeling the gut micr...