Safety, Reactogenicity, and Acceptability of a Placebo Dissolving Microneedle Patch in Children [0.03%]
儿童群体中溶解型安慰剂微针贴片的安全性、免疫原性和可接受性临床试验
Carol M Kao,Christina A Rostad,Peggy Kettle et al.
Carol M Kao et al.
Background and objectives: Dissolving microneedle patches (dMNPs) are a novel vaccine delivery method that may enhance acceptability and uptake. However, more data on their use in children is needed. ...
US Emergency Department Visits for Antibiotic Adverse Drug Events in Children, 2019-2023 [0.03%]
2019至2023年美国急诊因抗生素不良事件就诊的儿童患者数量
Andrew I Geller,Maribeth C Lovegrove,Katryna A Gouin et al.
Andrew I Geller et al.
This study analyzed US emergency department (ED) visits for antibiotic adverse drug events (ADEs) in children. Antibiotics were implicated in over one-third of pediatric ADE visits during 2019-2023, an estimated average of 47 628 ED visits ...
Cost-Effectiveness Analysis of a Text Message System for COVID-19 Testing for K-12 School Communities [0.03%]
用于K-12学校社区的Covid-19检测短信系统的成本效益分析
Maura Dougherty,Yelena P Wu,Leighann Kolp et al.
Maura Dougherty et al.
Background: During the COVID-19 pandemic, school closures led to loss of school-based resources and substantial learning losses for children. To facilitate the return to in-person learning, schools across the US partnered...
Cost-effectiveness of One-Time Universal Childhood Hepatitis C Screening in the United States [0.03%]
美国一次性普遍儿童期丙肝筛查的成本效益分析研究
Jessica Frankeberger,Melissa Choz,Tatyana Kushner et al.
Jessica Frankeberger et al.
Background: Hepatitis C Virus (HCV) in pregnancy has increased, leading to increased perinatally exposed infants. Although universal HCV screening in pregnancy is recommended, pediatric cases remain undiagnosed. We examin...
Pediatric Infectious Diseases Physicians' Preferences for Management of Clostridioides difficile Infection: An Emerging Infections Network (EIN) Survey [0.03%]
儿童难辨梭菌感染管理：新兴感染网络(EIN)调查中的传染病医生偏好分析
Alexandra Linn,Noah Boton,Susan E Beekmann et al.
Alexandra Linn et al.
We queried pediatric infectious diseases physicians via the Emerging Infections Network regarding management preferences for Clostridioides difficile infection (CDI). We explored use of vancomycin, fidaxomicin, bezlotoxumab and fecal microb...
HIV Cure Research: Ethical and Real-World Practical Considerations for Pediatric and Adolescent Populations [0.03%]
儿科和青少年艾滋病患者群体的艾滋病治愈研究：伦理和现实世界中的实际问题考虑因素
Elise Tirza Ohene-Kyei,Jessica Salzwedel,Karine Dubé et al.
Elise Tirza Ohene-Kyei et al.
HIV control off antiretroviral treatment (ART), ART-free remission, and cure remain elusive despite advancements in understanding their intricacies. Global data reveal that children and adolescents lag behind adults in ART access and in ach...
Lack of Discernible Benefit of High-Dose Aspirin in the Treatment of Kawasaki Disease [0.03%]
大剂量阿司匹林治疗川崎病利处不明显
Lavina Thadani,Huthaifah Khan,Kwang-Youn Kim et al.
Lavina Thadani et al.
In a retrospective single-center cohort study of 460 children with Kawasaki Disease, initial treatment with low-dose aspirin and IVIG resulted in similar coronary artery outcomes and IVIG retreatment rates compared to high-dose aspirin and ...
Still The Same Tune: Unchanged Antibiotic-Associated Adverse Event Rates Support the Need for Outpatient Antimicrobial Stewardship [0.03%]
依旧旧调：不变的抗菌药物相关不良事件率支持门诊抗菌药物管理的必要性
Ganga Moorthy,Matthew P Kronman
Ganga Moorthy
Although the overall average annual number of pediatric antibiotic-associated adverse events decreased during 2019-2023, the COVID-19 pandemic affected this outcome. Antibiotic-associated adverse events in 2023 alone were similar to histori...
Implementing Sustainable Meropenem Stewardship in Pediatric Care: Experience from a Public Hospital in a Middle-Income Country [0.03%]
儿科护理中可持续实施美罗培南管理的实践——中等收入国家公立医院的经验
Alejandro Diaz-Diaz,Jose Arias,Adriana Echavarria et al.
Alejandro Diaz-Diaz et al.
We evaluated a decade-long pediatric antimicrobial stewardship intervention targeting meropenem at a public hospital in Colombia. Structured preauthorization, prospective audit, and strengthened infection-control practices reduced meropenem...
Patient Characteristics and Microbiology in Pilonidal Abscesses in Children [0.03%]
儿童跟蹄窦脓肿患者的特点及微生物学研究
David Sebastian D Garcia,Joshua R Watson,Guliz Erdem
David Sebastian D Garcia
We described the microbiology of 216 pilonidal abscess episodes among 154 children over a 10-year period at a tertiary pediatric center and assessed patient characteristics associated with recurrence. Anaerobes and Streptococcus anginosus g...