Real-World Effectiveness of Rotavirus Vaccine against Rotavirus Disease among Children [0.03%]
轮状病毒疫苗对儿童轮状病毒感染的预防效果研究
Jacqueline E Tate,Samba O Sow,Awa Traore et al.
Jacqueline E Tate et al.
We estimated rotavirus vaccine effectiveness among children
Pediatric Dengue in Buenos Aires During the 2024 Outbreak: Clinical Presentation, Laboratory Findings, Viral Load, and Preexisting Immunity [0.03%]
布宜诺斯艾利斯2024年登革热疫情中的儿科病例：临床表现、实验室检查结果、病毒载量和既往免疫力
Sofía S Carril,Florencia A Bonnin,Maria S Tineo et al.
Sofía S Carril et al.
Background: In 2024, dengue cases reached unprecedented levels worldwide, with the Americas accounting for most cases. This study describes clinical and laboratory characteristics of dengue, comparing children and adolesc...
Lungs are only half the story: Programmatic shifts to prioritize pediatric extrapulmonary tuberculosis detection in high-burden settings [0.03%]
肺外结核不容忽视：优先设置儿童肺外结核检测项目的规划性转变
Meredith B Brooks,Giordano Sosa Soto,Jeffrey I Campbell et al.
Meredith B Brooks et al.
Pediatric extrapulmonary tuberculosis (EPTB) remains under-recognized due to biological, diagnostic, and systemic barriers. This Perspective outlines pragmatic, multilevel strategies-spanning frontline clinics to national systems-to strengt...
Safety of Dose 1 of the Nine-Valent Human Papillomavirus Vaccine in Children Aged 4-8 Years [0.03%]
九价人乳头瘤病毒疫苗1剂在4至8岁儿童中的安全性研究
Natalie Pierre-Joseph,Vishakha Sabharwal,Ruchita Borgaonkar et al.
Natalie Pierre-Joseph et al.
Data on the safety of the nine-valent human papillomavirus (9vHPV) vaccine in children younger than 9 years are limited. We conducted a single-center, open-label descriptive safety study of 150 healthy children aged 4-8 years who received d...
Victoria J L Konold,Adam W Brothers,Matthew P Kronman et al.
Victoria J L Konold et al.
Vancomycin is the first line antibiotic for resistant gram-positive infections, but can cause nephrotoxicity, ototoxicity, increased cost and healthcare utilization. We present an honorable memorial to this agent given the availability of s...
BNT162b2 2024-2025 Vaccine Effectiveness against COVID-19 in Children aged 6 months-17 years [0.03%]
6个月至17岁儿童接种BNT162b2新冠疫苗（2024-2025年）的有效性
Sara Y Tartof,Tara Ahi,Timothy B Frankland et al.
Sara Y Tartof et al.
In a test-negative case-control design among children aged 6 months-4 years (n=11,878) and 5-17 years (n=16,687) in Kaiser Permanente Southern California, BNT162b2 2024-2025 effectiveness against hospitalization/emergency department/urgent ...
Andrew S Haynes,Kira E Frappa,Matthew A Miller
Andrew S Haynes
In a satirical response, vancomycin defends its modern relevance by highlighting AUC-guided dosing, predictable pharmacokinetics, durability against resistance, and established clinical scenarios where it remains essential, while challengin...
HIV-Specific vs Universal Immunization Coverage in US Children with HIV: A Multi-Site Study [0.03%]
美国艾滋儿童的艾滋特异免疫和普遍免疫接种覆盖率多中心研究
Samie Sabet,Nicholas Hollman,Amy Hendrix-Dicken et al.
Samie Sabet et al.
Background: Immunization recommendations for children living with HIV (CLWH) differ from the general pediatric population due to increased risk of vaccine-preventable diseases. Adherence to these specific recommendations ...
Early Transition from Parenteral to Oral Antibiotics for Neonates with Bacteremic Urinary Tract Infections [0.03%]
早发性细菌尿路感染的新生儿由静脉注射抗生素向口服抗生素转换的研究
Tara L Greenhow,Kritika Amanjee,Okezi Obrutu et al.
Tara L Greenhow et al.
We conducted a retrospective cohort study of 49 neonates with bacteremic UTIs to assess efficacy of transition to oral antibiotics. Forty-one received oral step-down therapy after parenteral antibiotics; two had relapsed UTIs. No cases of b...
Brain Structure of South African Children Born to Mothers on Dolutegravir versus Efavirenz-Based Antiretroviral Therapy [0.03%]
东非国家出生儿童的母亲基于多替拉韦与依非韦伦的抗逆转录病毒治疗下的孩子大脑结构比较研究
Layla E Bradford,Catherine J Wedderburn,Thokozile R Malaba et al.
Layla E Bradford et al.
Background: The impact of in utero exposure to specific antiretroviral therapy (ART), particularly integrase strand transfer inhibitors, on early brain development remains poorly understood. We used magnetic resonance ima...