TMPRSS2 is dispensable for lethal SARS-CoV-2 BA.5 infection in humanized hACE2 golden hamsters [0.03%]
TMPRSS2在人源化hACE2金仓鼠感染SARS-CoV-2 BA.5致死过程中可有可无
Bowen Wang,Jinwei Zhang,Yuhan Li et al.
Bowen Wang et al.
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) can specifically bind to the angiotensin-converting enzyme 2 (ACE2) receptor on the host cell surface via the corresponding spike (S) protein, facilitating the entry of the virus. A...
Construction and validation of a nomogram predictive model for safety-related influencing factors in unilateral paracentesis kyphoplasty for spinal compression fractures [0.03%]
单侧经皮椎体后凸成形术治疗脊柱压缩性骨折安全相关影响因素预测模型的构建及验证
Jixiao Lang,Jingming Zhao,Rui Han et al.
Jixiao Lang et al.
Background: To explore the influencing factors on the safety of unilateral puncture kyphoplasty in the treatment of spinal compression fractures, and to construct and verify the nomogram prediction model. ...
Neuroinflammation and blood-brain barrier dysfunction in cerebral small vessel disease: mechanisms, biomarkers, and therapeutic implications [0.03%]
脑小血管病中的神经炎症和血脑屏障功能障碍:机制、生物标志物及治疗意义
Lixin Luo,Song Qiao
Lixin Luo
Cerebral small vessel disease (CSVD) is a chronic, progressive cerebrovascular disorder affecting small arteries, arterioles, venules, and capillaries, and is a leading contributor to stroke, vascular dementia, and cognitive impairment. Acc...
METTL14 knockdown mitigates HG-induced HK-2 cell apoptosis, inflammation, and ferroptosis by promoting SLC40A1 [0.03%]
METTL14敲低通过促进SLC40A1来缓解高糖诱导的HK-2细胞凋亡、炎症和铁死亡
Gang Jin,Juanru Zhao,Yan Liang et al.
Gang Jin et al.
Background: Diabetic nephropathy (DN) represents a leading cause of chronic kidney diseases worldwide. While solute carrier family 40 member 1 (SLC40A1) is involved in the regulation of iron homeostasis and iron transport...
COLEC10 and COLEC11 are new serum biomarkers of chronic liver disease [0.03%]
COLEC10和COLEC11是慢性肝病的新型血清生物标志物
Tongguo Yang,Yang Jing,Kun Li et al.
Tongguo Yang et al.
Background: COLEC10 and COLEC11 are presumed to act as pattern recognition receptors to activate the complement system by binding to MASP1. However, it is not clear whether the serum concentrations of COLEC10, COLEC11 and...
Acteoside prevents high-fat diet-induced obesity by regulating brown adipose tissue production, lipid metabolism, and the gut microbiota [0.03%]
绞股蓝皂苷通过调节棕色脂肪组织的产生、脂质代谢和肠道微生物群来预防高脂饮食诱导的肥胖症
Wenyu Ma,Chengyan Wang,Xiangfeng Jiang et al.
Wenyu Ma et al.
Acteoside, a phenylethanol glycoside, possesses various pharmacological properties. The aim of this study was to investigate the mechanism of its anti-obesity effects on high-fat diet (HFD)-induced obese mice, as well as to evaluate the ant...
Activated notch signaling pathway protects the intestinal barrier in DSS-induced colitis by regulating tight junctions [0.03%]
活化的诺特定价途径通过调节紧密连接保护DSS诱导的结肠炎中的肠道屏障功能
Tingting Li,Chong Geng,Xiao Li et al.
Tingting Li et al.
Background and aims: Studies have suggested that the activation of Notch pathway may provide protection to the intestinal mucosal barrier. However, the underlying mechanism remains to be elucidated. ...
Sevoflurane-induced hemispheric cerebral blood flow reduction in mice with revived global perfusion after carotid artery occlusion [0.03%]
异丙酚致颈动脉阻塞后复流小鼠半脑血流量降低
Rui Hao,Juchen Li,Jing Cang et al.
Rui Hao et al.
Background: Carotid artery disease (CAD) presents a significant risk for ischemic stroke. Understanding the pathophysiological changes following carotid artery occlusion, particularly regarding cerebral blood flow (CBF) a...
Prospective association between the triglyceride-glucose index and frailty in middle-aged and older adults: insights from a nationwide cohort study [0.03%]
基于全国队列研究的中老年人TG×GLU指数与衰弱前瞻性关联分析
Jingjing Hou,Song Zhao,Jieying Shi et al.
Jingjing Hou et al.
Background: Frailty is notably prevalent in individuals aged 50 and older and has been associated with metabolic dysfunction. The triglyceride-glucose (TyG) index is a reliable surrogate marker for insulin resistance. Thi...
Correction: Evaluating preoperative risk factors for deep vein thrombosis in elderly patients with hip fractures and chronic kidney disease: a retrospective study [0.03%]
纠正:老年股骨骨折合并慢性肾脏病患者深静脉血栓形成术前危险因素分析:回顾性研究
Ruili Jia,Xiaoqian Men,Fang Ran et al.
Ruili Jia et al.
Published Erratum
European journal of medical research. 2026 Jan 22;31(1):112. DOI:10.1186/s40001-026-03866-3 2026