Continuous glucose monitoring in non-diabetic populations: a systematic review of observational and interventional studies with meta-analysis [0.03%]
非糖尿病人群的持续葡萄糖监测：观察性和干预性研究的系统评价及meta分析
Xi Liao,Yongwei Li,Siwen Tang et al.
Xi Liao et al.
Background: Continuous glucose monitoring (CGM) has traditionally been used in diabetes management, but its application is expanding to non-diabetic populations for health promotion and metabolic optimization. However, th...
The interplay of APOE and APOA1 gene polymorphisms modulates the risk of type 2 diabetes mellitus in an obese population: a case-control study" [0.03%]
APOE和APOA1基因多态性在肥胖人群中相互作用可调节2型糖尿病风险：一项病例对照研究
Nagla Usama,Amr E Ahmed,Salma Mekheimer et al.
Nagla Usama et al.
Background: Genetic factors play an important role in metabolic disease susceptibility. Apolipoproteins E (APOE) and A1 (APOA1) are key regulators of lipid metabolism and have been individually associated with dyslipidemi...
The dual role of the Notch signaling pathway in digestive system cancers [0.03%]
Notch信号通路在消化系统肿瘤中的双重作用
Dairong Xiang,Tuokai Wang,Shihui Wei et al.
Dairong Xiang et al.
The Notch signaling pathway is critical for maintaining tissue homeostasis and plays dual roles in digestive system cancers, acting both as an oncogene and a tumor suppressor gene. This article explores its varied functions across esophagea...
Dexmedetomidine alleviates sepsis-associated acute kidney injury by inhibiting renal tubular ferroptosis via JNK/MAPK-LCN2 pathway [0.03%]
右美托咪定通过JNK/MAPK-LCN2信号通路抑制铁死亡来缓解脓毒症相关急性肾损伤
Boyang Liu,Shengxiang Ao,Li Luo et al.
Boyang Liu et al.
Background: Sepsis-associated acute kidney injury (SA-AKI), one of the most common complications of sepsis, significantly prolongs hospitalization, increases mortality, and elevates risks of cardiovascular events and chro...
Josef Stolberg-Stolberg,Iris Löscher,Fiona Charitou et al.
Josef Stolberg-Stolberg et al.
Background: Articular cartilage of weight-bearing joints restores its thickness after loading through viscoelastic recovery. Creep-recovery is a key parameter for assessing cartilage biomechanical properties and is releva...
Effect of glucagon-like peptide-1 receptor agonists on heart rate in non-diabetic individuals with overweight or obesity: a systematic review and pairwise and network meta-analysis of randomized controlled trials [0.03%]
葡萄糖似肽-1受体激动剂对超重或肥胖非糖尿病患者心率的影响：随机对照试验的系统评价和成对及网络meta分析
Yiwen Zhang,Chuying Zhang,Xuyang Gong et al.
Yiwen Zhang et al.
Objectives: To explore the association of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on heart rate (HR) in overweight or obese patients without diabetes. ...
Demographic and geographic hotspots of Alzheimer's disease and pneumonia-related mortality among older adults in the United States: a retrospective analysis [0.03%]
美国老年人阿尔茨海默病和肺炎相关死亡率的 demographics 和地理热点：一项回顾性分析
Muhammad Shaheer Bin Faheem,Shamikha Cheema,Muhammad Raza et al.
Muhammad Shaheer Bin Faheem et al.
Background: Older patients with Alzheimer's disease (AD) are more susceptible to pneumonia because of their limited mobility, malnourishment, and difficulty swallowing. This study highlights demographic and geographic whi...
Resistance exercise alleviates overactive bladder by attenuating detrusor oxidative stress via peroxynitrite reduction [0.03%]
抵抗性运动通过减少过氧亚硝酸盐缓解过度活动膀胱及逼尿肌氧化应激
Yangyun Wang,Jiewen Zhu,Shuying Dai et al.
Yangyun Wang et al.
Overactive bladder (OAB) remains challenging to treat due to drug intolerance and limited efficacy of behavioral therapies. The mechanistic basis by which exercise improves bladder function is poorly understood. Here, we established a clini...
Potential oncogene VPS72 in hepatocellular carcinoma: prognostic and immune infiltration implications [0.03%]
肝细胞癌中的潜在致癌基因VPS72：预后和免疫浸润意义
Manxian Huang,Xiaobing Wan,Juan Wu et al.
Manxian Huang et al.
Background: VPS72, primarily located in the nucleus, may play a role in hepatocellular carcinoma (HCC) progression. More research is required to assess if VPS72 mRNA or protein levels, along with clinical parameters, can ...
A novel mechanistic insight: BYHWD glycosides promote vascular endothelial repair via EPCs [0.03%]
一种新的机制见解：BYHWD苷通过EPC促进血管内皮修复
Fan-Chen Yan,Zheng-Ji Sun,Wei Tan et al.
Fan-Chen Yan et al.
Objective: To explore the mechanism of glycosides from BYHWD promote EPCs repairing damaged vascular endothelium. Methods: A model of v...