Development and evaluation of a nomogram model for predicting prolonged hospitalization after spinal tuberculosis focus decompression, fusion, and internal fixation surgery [0.03%]
脊柱结核病灶清除植骨内固定术后长期住院的列线图预测模型的构建与验证
Xu-Feng Jia,Qing-Zhong Zhou,Miao Long et al.
Xu-Feng Jia et al.
Background: Spinal tuberculosis remains a significant clinical challenge in high-prevalence regions. Despite advances in medical treatment, surgical interventions, such as debridement, decompression, and fusion, are often...
The safety and efficacy of GD2-targeted CAR-T cells in patients with neuroblastoma: a systematic review and meta-analysis [0.03%]
靶向GD2的CAR-T细胞治疗神经母细胞瘤患者的安全性和有效性：系统评价和meta分析
Mohammad Amin Habibi,Ali Zand,Behrouz Robat-Jazi et al.
Mohammad Amin Habibi et al.
Objectives: Neuroblastoma (NB) is a common and life-threatening pediatric solid tumor with a poor prognosis, especially in high-risk patients. Although anti-disialoganglioside GD2 (GD2) monoclonal antibodies improve survi...
Correlation between albumin-bilirubin score and comorbidity of cardiovascular disease and chronic kidney disease: insights from NHANES 2011-2018 [0.03%]
白蛋白-胆红素评分与心血管疾病和慢性肾脏病合并症的相关性：来自NHANES 2011-2018年的研究发现
Liang Fang,Jianfeng Yin,Anna Dai et al.
Liang Fang et al.
Background: Growing evidence indicates that cardiovascular disease (CVD), chronic kidney disease (CKD), and liver dysfunction share common pathophysiological pathways and constitute an interconnected syndrome. The albumin...
Ethanol extract of Dysosma versipellis induces cytotoxicity in colonic epithelial cells via activation of the PI3K-Akt/MAPK signaling pathways [0.03%]
三叶肉毒素乙醇提取物通过激活PI3K-Akt / MAPK信号途径在结肠上皮细胞中诱导细胞毒性
Shengyao Tang,Xiangyang Shao,Xiao Liu et al.
Shengyao Tang et al.
Background: Dysosma versipellis (DV) has pharmacological activity but causes toxicity, especially in nontargeted tissues such as the colon. Understanding its underlying mechanism is crucial for safety. ...
Diagnostic and prognostic utility of SIRI and CAR in necrotizing fasciitis: a retrospective cohort study on disease severity and clinical outcomes [0.03%]
SIRI和CAR在坏死性筋膜炎诊断及预后中的作用：一项关于疾病严重程度和临床结局的回顾性队列研究
Zheng Xu,Qi Han,Rui Zhang et al.
Zheng Xu et al.
Background: Necrotizing fasciitis (NF), a fulminant soft tissue infection requiring urgent surgical intervention, presents substantial diagnostic challenges due to its non-specific clinical manifestations during initial s...
Metabolomic insights: LC-MS profiling of human placental tissue from SSRI-treated pregnancies [0.03%]
代谢组学见解：SSRIs治疗妊娠的人胎盘组织的LC-MS分析
Anna Itkonen,Olli Kärkkäinen,Marko Lehtonen et al.
Anna Itkonen et al.
Antenatal depression, a common pregnancy complication, poses significant risks if untreated. Consequently, pregnant mothers are prescribed selective serotonin reuptake inhibitors (SSRIs). Based on their pharmacological action, SSRIs have th...
Pre-transplant physical performance, muscle quality, and body composition as predictors of post-liver transplant outcomes: a retrospective cohort study [0.03%]
移植前体力性能、肌肉质量和身体组成对肝移植后结局的预测价值：一项回顾性队列研究
Danial Fotros,Ghazaleh Mahdavi-Mazdeh,Zahra Yari et al.
Danial Fotros et al.
Background and aim: Sarcopenia, marked by muscle loss and weakness, is common in cirrhotic patients undergoing liver transplantation and is associated with poor postoperative outcomes. This study aimed to evaluate the imp...
Correlation and combined predictive value analysis of serum IL-6 and IL-10 levels with tumor progression in patients with cervical cancer [0.03%]
宫颈癌患者血清IL-6和IL-10水平的关联及联合预测价值分析
Li Cheng,Chunhua Guo,Yuxing Yang
Li Cheng
Objective: To investigate correlation between interleukin-6 (IL-6) and interleukin-10 (IL-10) levels in the serum of patients with cervical cancer and tumor progression, and to quantify predictive value of combined detect...
Effect of saponins from gynostemma pentaphyllum on iron metabolism in apolipoprotein E deficient mice [0.03%]
绞股蓝皂苷对载脂蛋白E基因缺陷小鼠铁代谢的影响
Tingyun Huang,Xin Xiao,Jimin Ma et al.
Tingyun Huang et al.
Background: Gynostemma pentaphyllum (GP) is known as the "elixir of life" in Guizhou Province, China, as it has been widely consumed by the elderly. Numerous studies have shown that gypenosides (GPS) extracted from GP are...
Development of a machine learning-based early prediction model for disease severity in acute pancreatitis [0.03%]
基于机器学习的急性胰腺炎病情严重程度早期预测模型的研发
Shengteng Guo,Fenfen Zhang,Xue Bai et al.
Shengteng Guo et al.
Background: Severe acute pancreatitis (SAP) represents the most severe form of acute pancreatitis (AP) and is associated with considerable morbidity, mortality, and socioeconomic burden. Early identification of critically...