Interactive analysis of single-cell trajectories in 3D space with Cell Journey [0.03%]
基于Cell Journey的单细胞轨迹的三维空间交互式分析
Damian Panas,Marcin Tabaka
Damian Panas
The integration of high-throughput single-cell profiling technologies with RNA velocity analysis has enabled the reconstruction of dynamic cellular differentiation trajectories at unprecedented resolution. Despite these advances, current vi...
Chromosome-level genome assembly and transcriptomes of the leaf insect Cryptophyllium westwoodii provide insights into the evolution of leaf-like masquerade [0.03%]
叶䗛伪装拟叶表型进化的基因组学和转录组学研究
Chuyang Mao,Zhiwei Dong,Zihe Li et al.
Chuyang Mao et al.
Background: Leaf insects in the family Phylliidae are regarded as nature's ultimate masqueraders, evolving the leaf-resembling morphology to avoid predation. However, the lack of a high-quality reference genome for the le...
Stereo-cell deciphers the spatial and functional heterogeneity of polyploid hepatocytes [0.03%]
立体细胞解析肝细胞多倍体的空间和功能异质性
Yongqing Yang,Jiahui Luo,Yier Cai et al.
Yongqing Yang et al.
A characteristic feature of the liver is the presence of numerous polyploid hepatocytes. However, the functional distinctions among diploid, tetraploid, and octoploid hepatocytes remain poorly understood. In this study, we employed the spat...
HYMET: A Hybrid Metagenomic Pipeline for Accurate and Efficient Taxonomic Classification [0.03%]
一种准确高效的元基因组分类分析流程HYMET
Inês Martins,Jorge Miguel Silva,João Rafael Almeida
Inês Martins
Background: Reliable taxonomic classification of metagenomic sequences remains constrained by high mutation rates, fragmented assemblies, and large heterogeneous reference databases. HYMET (Hybrid Metagenomic Tool) was de...
MIReVTD, a Minimum Information Standard for Reporting Vector Trait Data [0.03%]
MIReVTD 报告载体性状数据的最小信息标准
Sadie J Ryan,Paul J Huxley,Catherine A Lippi et al.
Sadie J Ryan et al.
Vector-borne diseases pose a persistent and increasing challenge to human, animal, and agricultural systems globally. Mathematical modeling frameworks incorporating vector trait responses are powerful tools for assessing risk and predicting...
ChronoRoot 2.0: An Open AI-Powered Platform for 2D Temporal Plant Phenotyping [0.03%]
ChronoRoot 2.0：一个开放的AI驱动的平台，用于二维时间序列植物表型分析
Nicolás Gaggion,Noelia A Boccardo,Rodrigo Bonazzola et al.
Nicolás Gaggion et al.
Background: Plant developmental plasticity, particularly in root system architecture, is fundamental to understanding adaptability and agricultural sustainability. Existing automated phenotyping solutions face limitations...
A comprehensive ruminant microbial catalog (CRMC) reveals convergent selection for key vitamin-synthesizing pathways and genes across ruminants and human [0.03%]
全面的反刍动物微生物目录（CRMC）揭示了反刍动物和人类中关键维生素合成途径和基因的趋同选择
Tong Feng,Yingjian Wu,Yixue Xu et al.
Tong Feng et al.
Background: The ruminant gastrointestinal tract (GIT) serves as a natural microbial reservoir in which vitamin-synthesizing microbes play key integrated roles in digestion, nutrient absorption, and metabolic balance; howe...
Comparative analysis of eccDNA and circRNA tools shows increased accuracy of tool combination [0.03%]
比较分析eccDNA和circRNA工具，组合使用工具可提高准确度
Aitor Zabala,Alex M Ascensión,Iñigo Prada-Luengo et al.
Aitor Zabala et al.
Introduction: Circular nucleic acids such as extrachromosomal circular DNA (eccDNA) and circular RNA (circRNA) are increasingly recognized for their biological relevance and potential as biomarkers in disease contexts. De...
Enhanced semantic classification of microbiome sample origins using Large Language Models (LLMs) [0.03%]
使用大型语言模型（LLM）增强微生物组样本来源的语义分类
Daniela Gaio,Janko Tackmann,Eugenio Perez-Molphe-Montoya et al.
Daniela Gaio et al.
Over the past decade, central sequence repositories have expanded significantly in size. This vast accumulation of data holds value and enables further studies, provided that the data entries are well annotated. However, the submitter-provi...
An Interpretable Graph-Regularized Optimal Transport Framework for Diagonal Single-Cell Integrative Analysis [0.03%]
一种可解释的图正则化最优传输框架用于对角单细胞整合分析
Zexuan Wang,Qipeng Zhan,Shu Yang et al.
Zexuan Wang et al.
Background: Recent advancements in single-cell omics technologies have enabled detailed characterization of cellular processes. However, coassay sequencing technologies remain limited, resulting in un-paired single-cell o...