FEDRANN: effective long-read overlap detection based on dimensionality reduction and approximate nearest neighbors [0.03%]
基于降维和近似最近邻的有效的长读段重叠检测算法FEDRANN
Jia-Yuan Zhang,Changjiu Miao,Teng Qiu et al.
Jia-Yuan Zhang et al.
Overlap detection is a key step in de novo genome assembly pipelines based on the Overlap-Layout-Consensus (OLC) paradigm. Existing methods for overlap detection either rely on heuristic seed-and-extension strategies or locality-sensitive h...
Synchrotron radiation micro-computed tomography of the small-spotted catshark embryonic development (Chondrichthyes: Scyliorhinus canicula) [0.03%]
小型斑猫鲨胚胎发育的同步辐射微计算机断层扫描（软骨鱼：小型斑猫鲨）
Elio Escamilla-Vega,Ann-Katrin Koch,Louk W G Seton et al.
Elio Escamilla-Vega et al.
Background: Sharks occupy a key position on vertebrate phylogeny, making them essential for understanding the early origins of jawed vertebrates (gnathostomes) and the functional adaptation of vertebrate traits like jaws ...
Autoencoder/RandomForest-TabPFN for Cross-Cancer Metabolomics: Prostate and Breast Cancer Diagnosis Using Paper Spray and Ion Mobility-Mass Spectrometry Techniques [0.03%]
基于自动编码器/随机森林-TabPFN的跨癌症代谢组学研究：使用纸喷雾和离子淌度-质谱技术进行前列腺癌和乳腺癌诊断
Sven Hauns,Frederico G Pinto,Costerwell Khyriem et al.
Sven Hauns et al.
Accurate and rapid disease diagnosis, particularly in prostate cancer (PC) and breast cancer (BC), is critical for early intervention and improved patient outcomes. Metabolomic signatures represent a robust molecular framework for elucidati...
Unlocking the Potential of Asian Genomic Data: A Collaborative Framework for Precision Medicine Innovation [0.03%]
释放亚洲基因组数据潜力：精准医学创新的协作框架
Asian genomic datasets possess unparalleled potential to advance global understanding of human genetic diversity. Encompassing the world's largest population pool with diverse ethnicities, these datasets capture comprehensive genomic variat...
Shiyu Du,Pengcheng Sun,Li Shen et al.
Shiyu Du et al.
Background: Single-cell RNA sequencing has emerged as a powerful approach to reveal cellular heterogeneity within biological systems. With the continuous advancement of high-throughput sequencing technologies, studies are...
METRIN-KG: A knowledge graph integrating plant metabolites, traits, and biotic interactions [0.03%]
METRIN-KG：一种整合植物代谢产物、性状和生物相互作用的知识图谱
Disha Tandon,Tarcisio Mendes De Farias,Pierre-Marie Allard et al.
Disha Tandon et al.
Background: In recent years, biodiversity data management has emerged as a critical pillar in global conservation efforts. Today, the ability to efficiently collect, structure, and analyze biodiversity data is central to ...
Integrative single-cell transcriptomics and proteomics reveal an immunometabolic framework for MSC-exosome-mediated remodeling of expanded NK cells [0.03%]
整合的单细胞转录组和蛋白质组揭示了MSC-外泌体介导的扩增NK细胞重塑的免疫代谢框架
Yunyun Fu,Yi Liu,Mingwen Xu et al.
Yunyun Fu et al.
Background: Natural killer (NK) cells play a central role in anti-tumor immunity and immunosurveillance of senescence, yet their clinical performance is frequently limited by functional exhaustion during ex vivo expansion...
Xiaoqiang Li,Cong Hua,Qian Yue et al.
Xiaoqiang Li et al.
GigaDB is a repository that links research articles with the underlying datasets, software, and metadata, helping to support open and reproducible research. As of February 2026, it contains 2,710 published datasets, covering 90.56 TB of dat...
Within-host diversity and phased variant analysis reveal structures and recombination of Helicobacter pylori subpopulations in stomach [0.03%]
胃内幽门螺旋杆菌亚群体的多样性及分型变异分析揭示了其结构和重组现象
Xiaomin Zhang,Hongjie Liu,Siyue Xu et al.
Xiaomin Zhang et al.
Helicobacter pylori (H. pylori) has a highly plastic genome and can generate substantial within-host diversity during chronic gastric colonization. However, the delineation of its within-host subpopulations, particularly regarding the emerg...