Jake M Holdreith,Jamie R Kurtz
Jake M Holdreith
Warren D Woessner,Robin A Chadwick
Warren D Woessner
Navigating the maze of IP/regulatory rights in the EU: the complex interaction between the SPC and Pediatric Regulations [0.03%]
在欧盟绕过知识产权/监管权利的迷宫：补充保护证书和儿科法规之间复杂的相互作用
Maria Isabel Manley,Marina Vickers
Maria Isabel Manley
Supplementary protection certificates on reformulations and new uses after Neurim: where do we go from here? [0.03%]
Neurim公司之后的适应症药物补充保护证书该如何进行改革与创新？
Garreth Duncan
Garreth Duncan
Devising a patent strategy to protect the IP of biologics in light of ambiguities, loopholes and pitfalls in the regulatory scheme [0.03%]
面对监管体系中的模糊性、漏洞和陷阱为生物药的知识产权制定专利策略
Benjamin C Hsing,Sapna W Palla
Benjamin C Hsing
Mary Anne Armstrong
Mary Anne Armstrong
The oral delivery of peptides and proteins: established versus recently patented approaches [0.03%]
肽和蛋白质的口服递送：已建立的方法与最近的专利技术
Louise Rosenmayr-Templeton
Louise Rosenmayr-Templeton
Over the past 30 years there has been significant research into technologies that promote the delivery of high molecular weight, poor membrane-permeable compounds across the gut. Most work has concentrated on the delivery of peptides and pr...
Pharmacological chaperones for enzyme enhancement therapy in genetic diseases [0.03%]
基因疾病中用于酶增强治疗的药物分子chasers
Juan Aymami,Xavier Barril,Laura Rodríguez-Pascau et al.
Juan Aymami et al.
Pharmacological chaperone therapy (PCT) is a rather new approach consisting in targeting incorrectly folded proteins by small molecules, thus, facilitating the correct folding of the protein and inducing a recovery of its functionality. Man...
Metabotropic glutamate receptor 5-positive allosteric modulators for the treatment of schizophrenia (2004-2012) [0.03%]
metabotropic谷氨酸受体5型阳性 allosteric调节剂治疗精神分裂症（2004-2012）
Craig W Lindsley,Shaun R Stauffer
Craig W Lindsley
The mGlu5, a class C G-protein-coupled receptor and member of the group I mGlu receptor family, has been demonstrated to play a role in a number of therapeutic areas within the CNS, including schizophrenia, dementia, epilepsy, cognition, dr...
Abhinav Kanwal,Sanjay K Banerjee
Abhinav Kanwal
Inhibiting sodium-glucose co-transporters (SGLT1/SGLT2), which have a key role in the absorption of glucose in the kidney and/or GI tract has been proposed as a novel therapeutic strategy for diabetes. Thus, screening and patenting of chemi...