Pharmacological corticosterone suppresses pro-inflammatory cytokine gene expression in a tissue-dependent manner independent of sleep fragmentation in male mice [0.03%]
药理学皮质酮以睡眠片段化独立的方式抑制小鼠组织依赖性促炎症细胞因子基因表达
Hunter J Weaver,Kimberly A Turner,Van Thuan Nguyen et al.
Hunter J Weaver et al.
Disrupted sleep from obstructive sleep apnea or insomnia promotes an inflammatory environment. Studies in mice have shown that experimental sleep fragmentation (SF) increases pro-inflammatory cytokine gene expression in brain and peripheral...
Context-dependent toxicity of human Tau isoforms in a Drosophila tauopathy model [0.03%]
果蝇Tau病模型中人类Tau异构体的上下文依赖性毒性
Yelena Ivanova,Miguel Ramirez-Moreno,Jie Liu et al.
Yelena Ivanova et al.
Tauopathies are characterised by progressive deterioration of brain regions due to abnormal accumulation of microtubule-associated protein tau (MAPT). Alternative splicing of MAPT pre-mRNA produces six isoforms, classified as 3R or 4R depen...
Three-dimensional analysis of spawning behaviour of skipjack tuna Katsuwonus pelamis using stereo-image measurements [0.03%]
利用立体影像测量分析黄鳍金枪鱼的产卵行为三维结构
Hiroto Yamamoto,Akira Sasaki,Tomoki Kanna et al.
Hiroto Yamamoto et al.
Although many pelagic fish species exhibit group spawning, the mechanisms underlying this mating system remain unclear; more fundamentally, detailed descriptions of group spawning behaviour itself are lacking. Here, the spawning behaviour o...
Conserved skeletal muscle transcriptomic responses to pacing strategies in Thoroughbred horses [0.03%]
赛马的骑乘策略对骨骼肌转录组的影响及应对策略
Kenya Takahashi,Kazutaka Mukai,Takanaga Shirai et al.
Kenya Takahashi et al.
This study investigated whether different pacing patterns during high-intensity exercise elicit distinct transcriptional responses in equine skeletal muscle. Eight Thoroughbred horses completed two treadmill exercise sessions in a randomize...
An open-source high-precision hive for long-term honeybee observation and research [0.03%]
一种开放式高精度蜂巢,用于长期观察和研究蜂蜜蜜蜂
Jiří Ulrich,Martin Stefanec,Tomáš Rouček et al.
Jiří Ulrich et al.
Honeybees have been of interest due to their important role in ecology and agriculture. Apis mellifera is a uniquely manageable eusocial insect, defined by its self-organising behaviour, extensive history of domestication and indispensable ...
Signaling through RXRb and its agonist, bexarotene, promotes neuron formation in Xenopus laevis embryos [0.03%]
RXRβ及其激动剂贝沙罗汀在非洲爪蟾胚胎神经元形成中的作用
D Lopes Cardoso,M Loizou,D D Fourla et al.
D Lopes Cardoso et al.
Retinoic acid, acting through RAR/RXR nuclear receptors, is required for neuronal differentiation in Xenopus laevis. Bexarotene, characterised as a pan-RXR agonist, reduces the symptoms of Alzheimer's disease (AD) in mouse models by clearin...
Testing the limits: the impact of extreme functional hip width on the muscular demands of walking [0.03%]
极端功能性髋关节外展对行走时肌肉需求的影响研究
Cristina Gildee,Patricia Ann Kramer
Cristina Gildee
The obstetrical dilemma (OD) posits that hominin pelvic morphology reflects a trade-off between obstetric demands and efficient bipedal locomotion- wider pelves facilitate childbirth but increase mechanical demands on stabilizing muscles, p...
Retraction: Assessment of seasonal, substrate and hormonal factors influencing the propagation and rooting of Camellia rubriflora's cuttings [0.03%]
撤稿:季节、基质和激素因素对红花山茶插条繁殖及生根影响的评估
Tinh Thi Nguyen,Vinh Thi Pham,Huong Thi Nguyen et al.
Tinh Thi Nguyen et al.
Opsin gene evolution in aquatic, amphibious and terrestrial blennies (Blenniidae) [0.03%]
鳚鱼视蛋白基因的演化:适应从水生到陆地的生活环境
Fabio Cortesi,Karen L Cheney,Georgina M Schlub et al.
Fabio Cortesi et al.
Evolutionary adaptations to life on land include changes to an animal's physiology, morphology and behaviour. The visual systems of amphibious fishes show pronounced morphological adaptations; however, whether molecular changes also occur r...
Katharina Gritsch,Klara Skrobar Martincic,Kristian Bredies et al.
Katharina Gritsch et al.
Lipid droplets are central hubs of cellular lipid metabolism and play crucial roles in health and disease. The yeast, Saccharomyces cerevisiae, serves as a powerful model for studying lipid droplet biology at the cellular level. Estimation ...