Acinar transformed ductal cells exhibit differential mucin expression in a tamoxifen-induced pancreatic ductal adenocarcinoma mouse model [0.03%]
在他莫昔芬诱导的胰腺导管腺癌小鼠模型中，小叶转化导管细胞的粘蛋白表达差异性研究
Kavita Mallya,Dhanya Haridas,Parthasarathy Seshacharyulu et al.
Kavita Mallya et al.
Pancreatic cancer (PC) is acquired postnatally; to mimic this scenario, we developed an inducible KrasG12D; Ptf1a-CreER™ (iKC) mouse model, in which Kras is activated postnatally at week 16 upon tamoxifen (TAM) administration. Upon TAM tre...
Going beyond conventional parameters to unveil sperm quality in fish: the use of fibre optic technology to assess mitochondrial respiratory performance [0.03%]
超越传统参数揭露鱼类精子质量的新方法——应用光纤技术评估线粒体呼吸功能
Lisa Locatello,Giovanni Rigoni,Maria E Soriano et al.
Lisa Locatello et al.
Sperm fertilisation success depends on both intrinsic quality and the interactions with the surrounding reproductive fluids. In several fish species, these interactions have a variable effect on sperm performance. Although specific response...
Going beyond conventional parameters to unveil sperm quality in fish: the use of fibre optic technology to assess mitochondrial respiratory performance [0.03%]
超越传统参数揭示鱼类精子质量：使用光纤技术评估线粒体呼吸功能
Lisa Locatello,Giovanni Rigoni,Maria E Soriano et al.
Lisa Locatello et al.
Sperm fertilisation success depends on both intrinsic quality and the interactions with the surrounding reproductive fluids. In several fish species, these interactions have a variable effect on sperm performance. Although specific response...
Tetraspanin18 regulates angiogenesis through VEGFR2 and Notch pathways [0.03%]
四跨膜蛋白 Tetraspanin18 通过血管内皮生长因子受体 2 和诺特定点通路调节血管生成
Grace X Li,Shaobing Zhang,Ren Liu et al.
Grace X Li et al.
The VEGF pathway is critically required for vasculogenesis, the formation of the primary vascular network. It is also required for angiogenesis resulting in sprouting and pruning of vessels to generate mature arborizing structures. The Notc...
Tetraspanin18 regulates angiogenesis through VEGFR2 and Notch pathways [0.03%]
四跨膜蛋白18通过血管内皮生长因子受体2和诺特定点调控血管生成
Grace X Li,Shaobing Zhang,Ren Liu et al.
Grace X Li et al.
The VEGF pathway is critically required for vasculogenesis, the formation of the primary vascular network. It is also required for angiogenesis resulting in sprouting and pruning of vessels to generate mature arborizing structures. The Notc...
The protective effects of human milk-derived peptides on the pancreatic islet biology [0.03%]
人乳源肽对胰岛生物学的保护作用
Amitoj Singh,Ashwantha Kumar Enjapoori,Yann Gibert et al.
Amitoj Singh et al.
Several epidemiological studies support the protective role of breastfeeding in reducing the risk for type 1 diabetes. Human breast milk is the perfect nutrition for infants and contains many complex proteins, lipids and carbohydrates. In t...
The protective effects of human milk-derived peptides on the pancreatic islet biology [0.03%]
人乳源性肽对胰岛生物学的保护作用
Amitoj Singh,Ashwantha Kumar Enjapoori,Yann Gibert et al.
Amitoj Singh et al.
Several epidemiological studies support the protective role of breastfeeding in reducing the risk for type 1 diabetes. Human breast milk is the perfect nutrition for infants and contains many complex proteins, lipids and carbohydrates. In t...
Mechanical and energetic determinants of impaired gait following stroke: segmental work and pendular energy transduction during treadmill walking [0.03%]
卒中后步态受损的机械和能量决定因素：踏车行走时的节段功及摆动能量转换
Gustavo Balbinot,Clarissa Pedrini Schuch,Henrique Bianchi Oliveira et al.
Gustavo Balbinot et al.
Systems biology postulates the balance between energy production and conservation in optimizing locomotion. Here, we analyzed how mechanical energy production and conservation influenced metabolic energy expenditure in stroke survivors duri...
The effects of temperature on the proxies of visual detection of Danio rerio larvae: observations from the optic tectum [0.03%]
温度对斑马鱼幼体视觉检测代理的影响：来自背侧丘脑的观察
Ewa Babkiewicz,Michał Bazała,Paulina Urban et al.
Ewa Babkiewicz et al.
Numerous studies have indicated that temperature improves the visual capabilities of different ectotherms, including a variety of fish species. However, none of these studies has directly tested whether elevated temperature extends the visu...
Phospholipids containing ether-bound hydrocarbon-chains are essential for efficient phagocytosis and neutral lipids of the ester-type perturb development in Dictyostelium [0.03%]
含有醚键脂链的磷脂对于高效的吞噬作用是必需的，而酯型中性脂则会扰乱Dictyostelium的发育过程
Frederik Kappelt,Xiaoli Du Ma,Bassam Abou Hasna et al.
Frederik Kappelt et al.
Lipids are the building blocks for cellular membranes; they provide signalling molecules for membrane dynamics and serve as energy stores. One path of their synthesis is initiated by glycerol-3-phosphate acyltransferase (GPAT), which in Dic...