How should retrospectively registered protocols be interpreted in systematic reviews? [0.03%]
如何在系统评价中解读事后注册的试验方案？
João Vitor Dos Santos Canellas,Fernando César Paraizo Borges
João Vitor Dos Santos Canellas
Prospective protocol registration is widely regarded as the preferred standard in systematic reviews. It promotes transparency from the outset of the research process, supports the prespecification of methods, contributes to reducing the ri...
Current evidence does not demonstrate decreased ICU length of stay and delirium incidence associated with the use of volatile sedation in critically ill patients: re-analysis of data from a recent systematic review [0.03%]
现有证据不支持吸入性镇静在危重病患者中使用与ICU住院时间缩短和谵妄发生率降低相关：近期系统评价数据的重新分析
Jiawen Deng
Jiawen Deng
Fever on hospital admission is associated with increased disease severity and mortality in acute pancreatitis: a systematic review and meta-analysis [0.03%]
发热与急性胰腺炎病情严重程度及病死率的关系：系统评价和-meta-分析
Eszter Pakai,Krisztian Klonfar,Anna Walter et al.
Eszter Pakai et al.
Background: Acute pancreatitis (AP) is often accompanied by changes in body temperature (Tb), but whether and how Tb at hospital admission is associated with the outcome of the disease remained unclear. Previous studies s...
Invisible but central: family caregiving as the hidden infrastructure of pediatric PKU-an integrative review [0.03%]
无形却重要：儿科苯酮尿症的家庭护理作为隐藏的基础设施-整合性回顾
Daria Słomińska,Łukasz Kałużny,Dariusz Walkowiak
Daria Słomińska
Background: Phenylketonuria (PKU) is a rare metabolic disorder requiring lifelong dietary management. While clinical stability hinges on strict treatment adherence, this adherence is largely sustained by unpaid family car...
Structural determinants and health-related quality of life among people living with HIV: a systematic review and meta-analysis protocol [0.03%]
HIV感染者的生活质量及其相关影响因素的系统综述和meta分析方案
Jason M Lo Hog Tian,Branden Ngo,Divya Parmar et al.
Jason M Lo Hog Tian et al.
Background: Antiretroviral therapy has increased life expectancy of people living with HIV, though estimates of quality of life remain consistently lower than that of the general population. Research on determinants of he...
Safety, immunogenicity, efficacy, and effectiveness of mpox vaccines in pregnant persons, children, and adolescents: a protocol for a living systematic review and meta-analysis [0.03%]
针对孕妇、儿童和青少年的猴痘疫苗安全性、免疫原性、有效性和效力：实时系统评价与meta分析方案
Jamile Ballivian,Agustín Ciapponi,Mabel Berrueta et al.
Jamile Ballivian et al.
Background: Mpox is a zoonotic disease caused by the monkeypox virus (MPXV) that became a global health concern following the 2022 outbreak. It poses a significant threat to immunocompromised individuals, children, and pr...
Understanding the role of qualitative evidence synthesis in health and social care guideline development: perspectives from guideline committee members and technical staff in a leading UK producer of health and social care guidelines [0.03%]
英国医疗及社会护理指南领军制订机构的指南委员会成员和技术人员认为质性证据综合在健康和社会照护指南制订中作用的探讨
Chris Carmona,Christopher Carroll,Susan Baxter
Chris Carmona
This paper explores the perceptions and experiences of guideline committee members and technical staff at the UK's National Institute for Health and Care Excellence (NICE) regarding the use of qualitative evidence syntheses (QES) in the gui...
Mental health screening in women with polycystic ovary syndrome: protocol for a systematic review and meta-analysis [0.03%]
多囊卵巢综合征女性的精神健康筛查：系统评价和 meta 分析方案
Rajalakshmi Rajendran,Marva Abdul Khader,Priya Shivanna et al.
Rajalakshmi Rajendran et al.
Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age and is reported frequently with mental health disorders. This systematic review aims to synthesize the availa...
A systematic scoping review on quality criteria for clinical practice guidelines for rare diseases [0.03%]
罕见病临床实践指南质量标准的系统性综述
Iméze J Hieltjes,Mirthe J Klein Haneveld,Ingeborg Van Dusseldorp et al.
Iméze J Hieltjes et al.
Background: Rare diseases impose substantial challenges on affected individuals and healthcare systems. While clinical practice guidelines (CPGs) are crucial for standardizing care, tools to assess their trustworthiness a...
Evaluating the efficacy of esmolol in septic shock: a systematic review and meta-analysis [0.03%]
艾斯莫尔在 Septic Shock 治疗中的疗效评估：系统回顾和荟萃分析
Retaj Al-Nafai,Ghaid Aljahdali,Lama Alrebish et al.
Retaj Al-Nafai et al.
Background: Persistent tachycardia in septic shock is associated with adverse outcomes, yet optimal management remains uncertain. Esmolol, a short-acting β1-selective blocker, has been investigated as a strategy to contr...