Ira Kukic,Felix Rivera-Molina,Derek Toomre
Ira Kukic
Background: Nearly all cells have a primary cilia on their surface, which functions as a cellular antennae. Primary cilia assembly begins intracellularly and eventually emerges extracellularly. However, current ciliogenes...
Swadhin Chandra Jana,Mónica Bettencourt-Dias,Bénédicte Durand et al.
Swadhin Chandra Jana et al.
The fruit fly, Drosophila melanogaster, is one of the most extensively studied organisms in biological research and has centrioles/basal bodies and cilia that can be modelled to investigate their functions in animals generally. Centrioles a...
Eight unique basal bodies in the multi-flagellated diplomonad Giardia lamblia [0.03%]
致病性寄生虫游走惠氏体中的八个独特的基体结构
Shane G McInally,Scott C Dawson
Shane G McInally
Giardia lamblia is an intestinal parasitic protist that causes significant acute and chronic diarrheal disease worldwide. Giardia belongs to the diplomonads, a group of protists in the supergroup Excavata. Diplomonads are characterized by e...
Colin A Johnson,Spencer J Collis
Colin A Johnson
Both inherited and sporadic mutations can give rise to a plethora of human diseases. Through myriad diverse cellular processes, sporadic mutations can arise through a failure to accurately replicate the genetic code or by inaccurate separat...
The cilia-regulated proteasome and its role in the development of ciliopathies and cancer [0.03%]
受纤毛调控的蛋白酶体及其在纤毛疾病和癌症发生发展中的作用研究
Christoph Gerhardt,Tristan Leu,Johanna Maria Lier et al.
Christoph Gerhardt et al.
The primary cilium is an essential structure for the mediation of numerous signaling pathways involved in the coordination and regulation of cellular processes essential for the development and maintenance of health. Consequently, ciliary d...
Susan K Dutcher,Eileen T O&#x;Toole
Susan K Dutcher
The unicellular green alga, Chlamydomonas reinhardtii, is a biflagellated cell that can swim or glide. C. reinhardtii cells are amenable to genetic, biochemical, proteomic, and microscopic analysis of its basal bodies. The basal bodies cont...
Zebrafish: a vertebrate tool for studying basal body biogenesis, structure, and function [0.03%]
斑马鱼：一种用于研究基底体发生的结构和功能的脊椎动物工具
Ryan A Marshall,Daniel P S Osborn
Ryan A Marshall
Understanding the role of basal bodies (BBs) during development and disease has been largely overshadowed by research into the function of the cilium. Although these two organelles are closely associated, they have specific roles to complet...
Sergey A Karpov
Sergey A Karpov
Phylum choanoflagellata is the nearest unicellular neighbor of metazoa at the phylogenetic tree. They are single celled or form the colonies, can be presented by naked cells or live in theca or lorica, but in all cases they have a flagellum...
Brunella Franco,Christel Thauvin-Robinet
Brunella Franco
Oral-facial-digital syndromes (OFDS) represent a heterogeneous group of rare developmental disorders affecting the mouth, the face and the digits. Additional signs may involve brain, kidneys and other organs thus better defining the differe...
Galo Garcia rd,Jeremy F Reiter
Galo Garcia rd
The basal body is a highly organized structure essential for the formation of cilia. Basal bodies dock to a cellular membrane through their distal appendages (also known as transition fibers) and provide the foundation on which the microtub...