Development of a method for the measurement of primary cilia length in 3D [0.03%]
一种在3D中测量原生纤毛长度的方法的发展
Taryn Saggese,Alistair A Young,Chaobo Huang et al.
Taryn Saggese et al.
Background: Primary cilia length is an important measure of cell and tissue function. While accurate length measurements can be calculated from cells in 2D culture, measurements in tissue or 3D culture are inherently diff...
Nancy K Kleene,Steven J Kleene
Nancy K Kleene
Background: Most cells in the body possess a single primary cilium. These cilia are key transducers of sensory stimuli, and defects in cilia have been linked to several diseases. Evidence suggests that some transduction o...
Live imaging of individual cell divisions in mouse neuroepithelium shows asymmetry in cilium formation and Sonic hedgehog response [0.03%]
活体小鼠神经上皮单细胞分裂成像显示鞭毛形成及Sonic Hedgehog信号应答的不对称性
Karolina Piotrowska-Nitsche,Tamara Caspary
Karolina Piotrowska-Nitsche
Background: Primary cilia are microtubule-based sensory organelles that play important roles in developmental signaling pathways. Recent work demonstrated that, in cell culture, the daughter cell that inherits the older m...