Transcriptomic and metabolomic insights into light-mediated unicellular-to-multicellular transition in Dictyostelium discoideum [0.03%]
柄眼虫门 Discoteliophora dictyostelioida 中光照介导的单细胞向多细胞转变的转录组和代谢组学见解
Yuehui Tian,Huiru Liu,Shanshan Xu et al.
Yuehui Tian et al.
Dictyostelium discoideum is a social amoeba that transitions from unicellular to multicellular forms in response to environmental signals, making it an intriguing model for studying cell aggregation and differentiation. Although previous st...
Effects of food availability on larval development during ontogenetic niche shift in a marine annelid [0.03%]
食物可获得性对海洋环节动物稚虫发育阶段生态位转换的影响
Nadine Randel
Nadine Randel
Many marine invertebrates have a biphasic life cycle with a free-swimming larva and a bottom-dwelling adult. The transition from a planktonic to a benthic lifestyle is a significant step in the animal's life history, highly regulated and in...
Yuta Nakai,Wanida Ono,Noriaki Ono
Yuta Nakai
The endosteum is a thin layer of connective tissue lining the inner surfaces of bones adjoining the medullary cavity. The endosteum houses a variety of cells crucial for bone growth, repair and remodelling, including bone-forming osteoblast...
Temperature and the progression of developmental milestones in embryogenesis of a marine ectotherm [0.03%]
温度对海洋冷血动物胚胎发育里程碑进展的影响
Emily K Belcher,Travis K Johnson,Christen Mirth et al.
Emily K Belcher et al.
Embryos are among the most temperature-sensitive life stages. To survive and produce juvenile stages, embryos must be robust to changes in temperature that also change development time profoundly. Yet, how robustness is achieved during embr...
Implications of canonical histone H3.1 and histone variant H3.3 in cancer [0.03%]
组蛋白H3.1和组蛋白变异型H3.3在癌症中的作用机制研究进展
Peng Wu,Li Wang,Ting Wen et al.
Peng Wu et al.
Histones are the fundamental building blocks of chromatin and serve as pivotal regulators of gene expression. Differential expression and mutations of H3.1 and H3.3 genes have been implicated in the pathogenesis of various cancer types. Mut...
An in silico pipeline identifies new neuropeptides and reveals a non-amidated regulator of muscle contraction in the freshwater cnidarian Hydra [0.03%]
一种计算流水线鉴定新的神经肽并揭示了水母Hydra中一种非酰胺类肌肉收缩调节因子
Pranav Prabhu,Puli Chandramouli Reddy
Pranav Prabhu
Neuropeptides play a critical role in neurotransmission and organismal development. Members of the phylum Cnidaria, with a diffused nervous system, are one of the earliest divergent animals and might provide insights into the fundamentals o...
A distinct phase of cyclin B (Cdc13) nuclear export at mitotic entry in Schizosaccharomyces pombe [0.03%]
酿酒酵母Schizosaccharomyces pombe进入有丝分裂时独特的cyclin B（Cdc13）核输出阶段
Samir G Chethan,Jessie M Rogers,Drisya Vijayakumari et al.
Samir G Chethan et al.
In eukaryotes, cell division requires coordination between the nucleus and cytoplasm. Entry into cell division is driven by cyclin-dependent kinases (CDKs), which need a cyclin binding partner for their activity. In Schizosaccharomyces pomb...
The E3 ligase MEX3B forms a tripartite complex with Rest and Hotair to determine the proliferative capacity of neural progenitor cells [0.03%]
E3连接酶MEX3B与Rest和Hotair形成三元复合物以决定神经干细胞的增殖能力
Kamakshi Garg,Gourav Sharma,Sarbani Samaddar et al.
Kamakshi Garg et al.
E3 ubiquitin ligases regulate the cellular proteome via proteasome-dependent protein degradation; however, there exist limited studies outlining their non-canonical functions. RNA-binding ubiquitin ligases (RBULs) represent a subset of E3 l...
Freshwater-adapted polychaetes exhibit a complete enzymatic machinery for synthesizing long-chain polyunsaturated fatty acids [0.03%]
淡水适应型多毛纲节肢动物具有合成长链多不饱和脂肪酸的完整酶系
Khalida Bainour,Nabilah Zulkifli,Ka-Kei Sam et al.
Khalida Bainour et al.
The sustainability of aquaculture is challenged by limited fishmeal and fish oil supplies, key sources of long-chain polyunsaturated fatty acids (LC-PUFA) such as eicosapentaenoic acid (EPA, 20:5 n-3), docosahexaenoic acid (DHA, 22:6 n-3) a...
The curious family of cytochrome P450 4F fatty acid ω-hydroxylases: recent developments in their function and relevance for human health [0.03%]
有趣的细胞色素P450 4F脂肪酸ω-羟基化酶家族：它们的功能及与人类健康的相关性方面的最新进展
Brisa Caroline Alves Chagas,Huiting Jia,Bjoern Brixius et al.
Brisa Caroline Alves Chagas et al.
Cytochrome P450 enzymes (CYP, P450) are indispensable for human health and catalyse a plethora of reactions contributing to the clearance of xenobiotics, steroid and bile acid biosynthesis, and the functionalization of vitamins in the human...