Michael H Kroll,Vahid Afshar-Kharghan
Michael H Kroll
Almost a trillion platelets pass through the pulmonary circulation every minute, yet little is known about how they support pulmonary physiology or contribute to the pathogenesis of lung diseases. When considering this conundrum, three ques...
Holding our breath: The emerging and anticipated roles of microRNA in pulmonary hypertension [0.03%]
屏住呼吸：微小rna在肺动脉高压中作用的展望及初步发现
Kevin White,Joseph Loscalzo,Stephen Y Chan
Kevin White
Over the past decade, the importance of non-coding RNA such as microRNA has been established in numerous processes that drive human pathogenesis. These crucial molecular regulators modulate networks of target gene transcripts that, in turn,...
Are men at risk? The role of testosterone in cardiovascular morbidity [0.03%]
男人也会受威胁吗？——睾丸素与心血管疾病的关系
Premanand C Sundivakkam,Ankit A Desai,Kimberly A Smith et al.
Premanand C Sundivakkam et al.
Is surgical treatment the cure for patients with congenital heart disease? [0.03%]
先天性心脏病患者手术治疗就能药到病除？
Antonio Augusto Lopes
Antonio Augusto Lopes
Stuart Rich
Stuart Rich
Critical care rehabilitation - is it the answer for reducing morbidity in ARDS survivors? Regarding "Acute respiratory distress syndrome: A clinical review" [0.03%]
关于ARDS幸存者减少后遗症的危重症康复治疗？——相关文献述评"急性呼吸窘迫综合征：临床综述"
Abraham Samuel Babu,Lenny T Vasanthan
Abraham Samuel Babu
Massive dilatation of the pulmonary artery in association with pulmonic stenosis and pulmonary hypertension [0.03%]
肺动脉狭窄和肺动脉高压伴发的肺动脉巨大扩张
Sejal Morjaria,Dan Grinnan,Norbert Voelkel
Sejal Morjaria
Congenital pulmonary valve stenosis has been associated with the development of massive pulmonary arterial (PA) dilatation. Over time, this dilatation may distort surrounding structures and lead to compression of the left main coronary arte...
Partial anomalous pulmonary venous return presenting with adult-onset pulmonary hypertension [0.03%]
成人后天性肺动脉高压合并部分型肺静脉异常回流畸形的诊治挑战及思考——一例报告并文献复习
Edmund H Sears,Jason M Aliotta,James R Klinger
Edmund H Sears
Partial anomalous pulmonary venous return (PAPVR) is a rare cause of adult onset pulmonary arterial hypertension (PAH) that can present with a wide spectrum of severity from early childhood throughout adult life. We present two patients wit...
Distinct responses to hypoxia in subpopulations of distal pulmonary artery cells contribute to pulmonary vascular remodeling in emphysema [0.03%]
远端肺动脉细胞亚群对缺氧的差异反应可导致肺气肿患者的肺血管重塑
L S Howard,A Crosby,P Vaughan et al.
L S Howard et al.
We have shown previously that hypoxia inhibits the growth of distal human pulmonary artery smooth muscle cells (PASMC) isolated under standard normoxic conditions (PASMC(norm)). By contrast, a subpopulation of PASMC, isolated through surviv...
Activation of the unfolded protein response is associated with pulmonary hypertension [0.03%]
未折叠蛋白反应的激活与肺动脉高压相关
Michael E Yeager,Monica B Reddy,Cecilia M Nguyen et al.
Michael E Yeager et al.
Pulmonary hypertension remains an important cause of morbidity and mortality. Although there is currently no cure, descriptions of defective intracellular trafficking and protein misfolding in vascular cell models of pulmonary hypertension ...