MetF-Dependent Methionine Biosynthesis Is Required for Mycobacterium tuberculosis Survival and In Vivo Persistence [0.03%]
MetF依赖的蛋氨酸生物合成对结核分枝杆菌的存活和体内持续感染是必需的
Ikue Tosa,Tomoki Kitahara,Katsuki Takebe et al.
Ikue Tosa et al.
Methionine biosynthesis is essential for Mycobacterium tuberculosis, but the in vivo relevance of individual enzymes remains unclear. We performed transposon sequencing in Mycobacterium bovis BCG under methionine-free conditions and identif...
Effects of Different Living Environments on Intestinal Flora in Patients With Schistosoma Japonicum-Induced Liver Fibrosis [0.03%]
不同生活环境对日本血吸虫病肝纤维化患者肠道菌群的影响
Xiaofei Fan,Chen Zhou,Pengpeng Zhang et al.
Xiaofei Fan et al.
Schistosomiasis japonica is a parasitic disease leading to liver cirrhosis. China's "fishermen going ashore" policy divides patients with schistosomiasis liver fibrosis into two groups: those near the infected waters and those inland far fr...
Mitochondrial Genome Reduction and Accelerated Evolution in Planktonic Foraminiferans [0.03%]
浮游有孔虫线粒体基因组的简化与加速演化
Hsin-Tung Lai,Ming-Wei Lai,Tzu-Haw Wang et al.
Hsin-Tung Lai et al.
The evolution of mitochondria provides crucial insights into the diversification of eukaryotes, with complex events of gene losses revealed through comparative analyses of mitochondrial genomes (mitogenomes) across eukaryotic lineages. Howe...
Decoding Akkermansia muciniphila Effector Biology: From Microbial Molecules to Host Outcomes [0.03%]
解码Akkermansia muciniphila效应物生物学：从微生物分子到宿主效应
Amir Arsalan Ghahari,Ainur Sadykova,Salim Davlatov et al.
Amir Arsalan Ghahari et al.
Akkermansia muciniphila is increasingly linked to host metabolic, immune, and neurobehavioral phenotypes, yet taxon-level associations are often inconsistent across studies and disease contexts. This review advances an effector-centered fra...
Water Soluble-Nitrogenous Secondary Metabolites From Talaromyces annesophieae MD2 Exhibit Anti-Bacterial, Anti-Cancer, Anti-Oxidant, and Cytoprotective Activities [0.03%]
可溶性氮次生代谢产物具有抗菌，抗肿瘤，抗氧化和细胞保护活性
Meryem Doymus-Yilmaz,Huseyin Aksit,Mesut Taskin
Meryem Doymus-Yilmaz
This study focused on biological activities and chemical characterization of secondary metabolites from the fungus Talaromyces annesophieae MD2 (GenBank: PQ252671). The dichloromethane extract (DCM-E) of its culture supernatant was fraction...
Comparative Analysis of Chlorhexidine Derivatives and Alternative Agents on Streptococcus mutans Viability, Biofilm Formation, and Gene Expression [0.03%]
氯己定衍生物和替代剂对变异链球菌存活率、生物膜形成及基因表达的比较分析
Hamideh Kamalloo,Mohammadreza Moeininejad,Maryam Kiani Golshoui et al.
Hamideh Kamalloo et al.
This study evaluates the antimicrobial and antibiofilm effects of chlorhexidine and related compounds against S. mutans, focusing on bacterial viability, biofilm formation, and expression of key biofilm genes. Eight compounds were tested fo...
Comparative Study
MicrobiologyOpen. 2026 Aug;15(4):e70360. DOI:10.1002/mbo3.70360 2026
From Oral Candidiasis to Candidemia: A Review of Superficial to Invasive Progression [0.03%]
从口腔念珠菌病到念珠菌血症：浅表至侵袭性发展的综述分析
Julia Robledo Jerez,Marcella Vieira Ambrosio,Marcela Eduarda Olegario Fernandes et al.
Julia Robledo Jerez et al.
Oral candidiasis is the most prevalent fungal infection of the oral cavity and is frequently associated with immunosuppression. Although traditionally classified as a superficial condition, growing evidence suggests that oral infection with...
Hamed Tahmasebi,Aisa Bahar,Meisam Khazaei et al.
Hamed Tahmasebi et al.
Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effec...
Effects of the HDAC6/8 Inhibitor MC1568, Alone and in Combination With Fluconazole, in Non-Albicans Candida Species Infections [0.03%]
HDAC6/8抑制剂MC1568及其与氟康唑联合用于非白念珠菌属感染的效果研究
Andrea Giammarino,Chiara Lambona,Alessia Raucci et al.
Andrea Giammarino et al.
Fungal infections pose a severe health risk, particularly in immunocompromised individuals, with Candida species being a leading cause of bloodstream infections. The rise of non-albicans Candida (NAC) infections, accounting for 35%-65% of c...
Detection of OXA-23 Among Carbapenem-Resistant Acinetobacter baumannii Isolated From Intensive Care Units of a Tertiary Care Hospital in Pakistan [0.03%]
巴基斯坦一家三级护理医院重症监护室耐碳青霉烯类baumannian不动杆菌中OXA-23的检测
Hafsa Waseem,Ihsan Ullah,Shahzad Ahmad et al.
Hafsa Waseem et al.
Carbapenem-resistant Acinetobacter baumannii (CRAB) has been designated a top-priority critical pathogen by the World Health Organization, and the CDC has also classified it as a serious and immediate public health threat. The Cross-section...