Measuring the Effects of Cannabis on Anxiety and Depression Among Cancer Patients [0.03%]
测量大麻对癌症患者焦虑和抑郁的影响
Apoorva C Reddy,John M Hampton,Susan J Park et al.
Apoorva C Reddy et al.
Introduction: Cancer patients are increasingly turning to cannabis products to modulate physical and psychological symptoms despite limited evidence supporting their efficacy. We aimed to explore cancer patients' self-rep...
Clinical Benefits of Combination Immunotherapy Over Standard Immunotherapy Monotherapy in Previously Treated Advanced Esophageal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis [0.03%]
联合免疫疗法对比标准免疫单药治疗先前接受过治疗的晚期食管鳞癌患者的临床获益：系统性回顾和 meta 分析
Yong Chen,Zixuan Chen,Hong Guo et al.
Yong Chen et al.
Purpose: Programmed cell death protein 1 (PD-1) inhibitor monotherapy is the standard second-line treatment for esophageal squamous cell carcinoma (ESCC), but the clinical response and survival outcomes still remain unsat...
Meta-Analysis
Cancer medicine. 2025 Nov;14(21):e71329. DOI:10.1002/cam4.71329 2025
Impact of Age on Early CAR T-Cell Therapy Toxicity: A Propensity Score Matching Analysis [0.03%]
年龄对早期CAR-T细胞治疗毒性的影响：倾向评分匹配分析
Jia Yi Tan,Yong-Hao Yeo,Qi Xuan Ang et al.
Jia Yi Tan et al.
Introduction: Despite the growing use of CAR-T therapy, adults over 65 still receive this treatment less frequently than younger patients. Methods: ...
LIF/LIFR Signaling in Gastric Cancer: A Double-Edged Sword in Tumor Progression and Therapeutic Resistance [0.03%]
胃癌中LIF/LIFR信号通路在肿瘤进展和耐药中的双刃剑作用
Daniel Park,Kyung-Il Kim,Yate-Ching Yuan et al.
Daniel Park et al.
Gastric cancer (GC) remains a major cause of cancer-related mortality worldwide, driven by late-stage diagnoses and poor survival outcomes. Leukemia inhibitory factor (LIF) and leukemia inhibitory factor receptor (LIFR) are increasingly rec...
Associations Between Neighborhood Environment, Childhood Adversity, and Cancer Risk: A Geospatial Analysis [0.03%]
邻里环境、童年逆境与癌症风险的关联性——一种地理空间分析方法
Tesla D DuBois,Shannon M Lynch,Jayme Banks et al.
Tesla D DuBois et al.
Objective: Using a socio-ecological perspective that includes consideration for the effects of the built environment, this study investigated the association between neighborhood-level measures of childhood trauma, adult ...
Metabolic Reprogramming in Lung Cancer: Hallmarks, Mechanisms, and Targeted Strategies to Overcome Immune Resistance [0.03%]
肺癌代谢重组：标志、机制及克服免疫抵抗的靶向策略
Yi Chen,Menglin Bai,Ming Liu et al.
Yi Chen et al.
Background: Lung cancer remains the leading cause of cancer-related mortality worldwide. Although immunotherapy has revolutionized lung cancer treatment, its efficacy is often hindered by primary and acquired immune resis...
Employment Status Among Brazilian Women With Estrogen Receptor-Positive Nonmetastatic Breast Cancer [0.03%]
巴西绝经后雌激素受体阳性非转移性乳腺癌女性患者就业状况调查
Daniele Assad-Suzuki,Luciana Castro Garcia Landeiro,Danielle Laperche-Santos et al.
Daniele Assad-Suzuki et al.
Background: Employment is a critical determinant of quality of life, social reintegration, and financial stability for breast cancer survivors. International studies have shown that return-to-work (RTW) rates vary widely,...
Multicenter Study
Cancer medicine. 2025 Nov;14(21):e71306. DOI:10.1002/cam4.71306 2025
Targeting Tumorigenic Coactivators in the PI3K/AKT Signaling Pathway: A Novel Approach for Cancer Treatment [0.03%]
靶向PI3K/AKT信号通路中的致癌共激活因子：癌症治疗的新方法
Md Anwarul Haque,Thanasis Poullikkas,F M Al-Amin Kaisar et al.
Md Anwarul Haque et al.
Objective: This study aims to explore the persistent activation of the PI3K/AKT signaling pathway in various cancers, with a focus on upstream coactivators that drive tumor growth and contribute to therapeutic resistance....
Associations of Commonly Used Concomitant Medications With Survival and Adverse Event Outcomes in Breast Cancer [0.03%]
乳腺癌患者中常用伴随用药与生存率和不良事件之间关系的研究
Natansh D Modi,Ahmad Y Abuhelwa,Nicole M Kuderer et al.
Natansh D Modi et al.
Background: The impact of commonly used non-cancer medications on breast cancer outcomes remains underexplored in large datasets. Aims: ...
Real-World Adherence to Repeat Colorectal Cancer Screening With the Multi-Target Stool DNA Test in a Large, Insured, and Average-Risk Population [0.03%]
大型保险人群结直肠癌多靶点粪便DNA复筛依从性的现实世界研究
Mallik Greene,Joseph Anderson,Joseph LeMaster et al.
Mallik Greene et al.
Introduction: Guidelines recommend starting average-risk colorectal cancer (CRC) screening at age 45 years, and thereafter repeating screening tests at regular intervals. However, US screening rates are currently suboptim...