Unveiling the protective efficacy of rutin against High-Sucrose Diet-induced oxidative stress, biochemical alterations, and organismal hazards in Drosophila melanogaster [0.03%]
染料木黄酮揭开了富含果糖的西方饮食诱导的代谢应激及其改善措施的秘密：以果蝇为模型的研究发现
Abhratanu Ganguly,Kanchana Das,Sayantani Nanda et al.
Abhratanu Ganguly et al.
Sucrose is a common ingredient in many foods. However, intake of High-Sucrose Diet (HSD) for a longer duration can fuel metabolic and physiological issues. Hence, continuous efforts implying animal models are essential to mitigate the adver...
Avocado (Persea americana) pulp extract mitigates the testicular oxidative stress and inflammation induced by cadmium in male rats [0.03%]
avocado（Persea americana）果肉提取物缓解雄性大鼠镉诱导的睾丸氧化应激和炎症作用
Mahemed Akeel,Gamal Mohamed,Ahmed G Hamad et al.
Mahemed Akeel et al.
One environmental contaminant that affects several tissues and organs, including the testis, is cadmium (Cd). Persea americana is a distinctive fruit with remarkable nutritional and technological qualities in addition to possible health ben...
Taiqiang Jiao,Ling Yuan,Jiaqing Li et al.
Taiqiang Jiao et al.
The Maxing Kugan Decoction (MKD) is a traditional Chinese medicine prescription specifically designed for respiratory infectious diseases in the northwest region, particularly targeting influenza during the winter and spring seasons. While ...
Nephrotoxic effects of combined exposure to 85 dB(a) noise and 300 ppm toluene in Wistar rats: biochemical and histopathological analysis [0.03%]
85dB(A)噪声和300ppm甲苯联合作用于Wistar大鼠的肾毒性：生化及病理分析
Takoua Ben Attia,Eduardo Alberto López-Maldonado,Said Galai et al.
Takoua Ben Attia et al.
Toluene, a widely used industrial solvent, and environmental noise, a pervasive physical stressor, are both recognized for their harmful effects on health. This study examined the individual and combined effects of toluene and noise exposur...
Curcumin nanoparticles ameliorates cardiac toxicity through modulation of oxidative stress, apoptosis, inflammation, and DNA damage in rat [0.03%]
姜黄素纳米颗粒通过调节大鼠氧化应激、凋亡、炎症和DNA损伤来改善心脏毒性
Ehab Tousson,Doha Mohammad Beltagy,Nagat Fawzy Nawar et al.
Ehab Tousson et al.
Recent studies have highlighted the toxicological impact of nanoparticles, including their role in malignancies and various organ system dysfunctions, however, the effects of nanoparticles on the cardiovascular system remain underexplored. ...
Biosynthesis of zinc oxide nanoparticles using Sideritis akmanii plant and evaluation of its biological activity [0.03%]
利用植物Sideritis akmanii合成氧化锌纳米粒子及其生物活性评估
Arzu Özkara,Doğukan İşlek
Arzu Özkara
In this study, zinc oxide nanoparticles (ZnONPs) were synthesized by green synthesis technique using the extract obtained from Sideritis akmanii plant and the obtained ZnONPs were characterized by Ultraviolet-Visible Spectrophotometry (UV-V...
Effect of theophylline on vascular tissue in a model of oxidative stress induced by titanium dioxide nanoparticles [0.03%]
二氧化钛纳米粒子诱导氧化应激模型中咖啡因对血管组织的影响研究
F M Treviño-González,R M Chávez-Morales,F P Pacheco-Moisés et al.
F M Treviño-González et al.
Exploring the causal relationship and molecular mechanisms between Methyl-4-hydroxybenzoic acid (MEP) and Alzheimer's disease: a mendelian randomization, multi-omics, and network toxicology approach [0.03%]
探讨对羟基苯甲酸甲酯（MEP）与阿尔茨海默病的因果关系及分子机制：孟德尔随机化、多组学和网络毒理学研究
Hong Gong,Jiayu Li,Rong Pu et al.
Hong Gong et al.
The pathogenesis of Alzheimer's disease remains incompletely understood. Methyl-4-hydroxybenzoic acid, a common chemical additive, may play a role, though its mechanisms are unclear. This research investigated the potential causal link betw...
Influence of senescence on the sensitization potential of chemicals detected by local lymph node assays in aged mice [0.03%]
衰老对老龄小鼠化学物质敏化潜能局灶性淋巴结试验的影响研究
Koji Ishida,Mao Kaneki,Chiharu Ohira et al.
Koji Ishida et al.
The global population is aging rapidly, posing new challenges for the safety evaluation of chemicals. Most toxicity studies use suitably aged animals that resemble healthy adults if they have similar responses. However, this assumption may ...