Oxidative stress-mediated mitochondrial damage and apoptosis induced by typical iodoalkanes from shale gas wastewater [0.03%]
典型页岩气废水中的碘代烷对细胞产生氧化应激损伤并诱导线粒体介导的细胞凋亡作用机制研究
Jing An,Na Li,Jingjing Jiang et al.
Jing An et al.
Iodide organic compounds, the conversion reaction by-products in shale gas wastewater, have potential risks to ecological environment and human health. However, information about their negative effects and molecular mechanism remains limite...
Alteration in oxidative stress markers and metabolic profile of the third instar larvae of transgenic drosophila exposed to apigenin and bis(2-ethylhexyl) phthalates [0.03%]
金光菊苷和邻苯二甲酸二异辛酯对转基因果蝇三龄幼虫氧化应激标志物和代谢轮廓的影响
Kajal Gaur,Yasir Hasan Siddique
Kajal Gaur
Bis-(2-ethylhexyl) phthalate commonly called (DEHP) is a major environmental contaminant known to interfere with various biological pathways following human exposure. Our previous research demonstrated that Bis(2-ethylhexyl) phthalates incr...
Study of mechanism of drug-induced liver injury caused by pyrethroid insecticides based on network toxicology and mendelian randomization [0.03%]
基于网络毒理学和孟德尔随机化的拟除虫菊酯类农药药物性肝损伤致病机制研究
Jian-Xing Li,Qi-Qi Gan,Yun Xia
Jian-Xing Li
The widespread use of pyrethroid insecticides poses a public health hazard, and previous studies have shown that these insecticides may contribute to liver injury, but the mechanism of action has not been comprehensively investigated. The d...
Immune modulatory potential of Carica papaya against asbestos-induced acute lung injury through down-regulation of NF-kB and MAPK pathways [0.03%]
木瓜蛋白酶通过下调NF-KB和MAPK途径对石棉引起的大鼠急性肺损伤的免疫调节作用研究
Usman Haider,Bilal Aslam,Shamshad Ul Hassan et al.
Usman Haider et al.
Inflammation is the primary response to any sort of injury that provokes an immune system and release of inflammatory mediators. The aim of current study is to explore the anti-inflammatory and therapeutic potential of Carica papaya against...
Integrative In vitro and In Silico analysis of marine Actinobacterium, Streptomyces rubrogriseus-derived metabolites as quorum sensing inhibitors against Chromobacterium violaceum [0.03%]
从海洋放线菌链霉菌红灰色变种中提取的代谢产物作为紫檀色假单胞菌型群体感应抑制剂的集成体外和计算机分析
Ambily Balakrishnan,Kottayath G Nevin,Arunkumar Gangadharan et al.
Ambily Balakrishnan et al.
Quorum-sensing (QS), a bacterial communication mechanism regulating virulence, biofilm formation, and environmental adaptation, represents a promising target for antivirulence therapies. Unlike conventional antibiotics, QS inhibition disrup...
Heavy metal concentration and DNA damage in tilapia (Oreochromis niloticus linnaeus, 1758) and catfish (Clarias gariepinus Burchell, 1822) from contaminated Ala River, Akure, Nigeria [0.03%]
尼日利亚阿库雷市受污染的阿拉河中尼罗罗非鱼(Oreochromis niloticus Linnaeus，1758)和非洲鲶鱼(Cliarias gariepinus Burchell，1822)中的重金属浓度和DNA损伤
Okunola Adenrele Alabi,Foyinsola Mabel Fatile,Michael Olufemi Ashamo
Okunola Adenrele Alabi
This study investigated heavy metal contamination in Clarias gariepinus, Oreochromis niloticus, and water from the polluted Ala River using atomic absorption spectroscopy. Carcinogenic and non-carcinogenic risks were assessed per USEPA guid...
Computational and experimental assessment of the toxicological effects of copper oxide nanoparticles on haematological and biochemical parameters in albino mice [0.03%]
计算评估和实验评估氧化亚铜纳米颗粒对白鼠血液学及生化指标的毒理效应
Muhammad Yasir Abbas,Ali Umar,Muhammad Waseem Aslam et al.
Muhammad Yasir Abbas et al.
The investigation delves into biological interactions of CuO-NPs throughout study focusing on their synthetic structure together with their functional characteristics and their dangerous nature. The production of CuO-NPs happened when coppe...
Hülya Tezel Yalçın,Deniz Arca Çakır,Anıl Yirün et al.
Hülya Tezel Yalçın et al.
Gibberellic acid induced oxidative stress, mitochondrial division/fusion imbalance, and autophagy in the ovary of Carassius auratus [0.03%]
赤霉素诱导的大鳞马口鱼卵巢氧化应激、线粒体分裂/融合失衡及自噬反应
Shan Chen,Lingling Guo,Runjie Ou et al.
Shan Chen et al.
Gibberellic acid (GA3), a widely used plant growth regulator, has the potential to enter the animal food chain. However, there is limited information regarding its reproductive toxicity in female fish. This study aimed to elucidate the pote...
Protective effects of Melissa officinalis against Chlorpyrifos-induced hepatotoxicity in rat: a dose-dependent evaluation of biochemical, histological, and oxidative stress markers [0.03%]
牻牛儿菊酯诱导的肝毒性大鼠血清、组织生化、病理和氧化应激标志物的剂量依赖性评价及柠檬香蜂草的保护作用
Fatemeh Alijaniha,Fatemeh Emadi,Zahra Bahaeddin et al.
Fatemeh Alijaniha et al.
Chlorpyrifos (CPF) is a widely used pesticide known for its hepatotoxic effects. Melissa officinalis L. is a medicinal herb, recognized in Persian medicine for its diverse biological activities and protective effects against poisons. This s...