rpoS-mutation variants are selected in Pseudomonas aeruginosa biofilms under imipenem pressure [0.03%]
在亚胺培南压力下粘液型肺炎克雷伯菌中 selections 基因的突变体 biến异体被选择出来
Xiangke Duan,Yanrong Pan,Zhao Cai et al.
Xiangke Duan et al.
Background: Pseudomonas aeruginosa is a notorious opportunistic pathogen causing various types of biofilm-related infections. Biofilm formation is a unique microbial strategy that allows P. aeruginosa to survive adverse c...
SARS-CoV-2: from its discovery to genome structure, transcription, and replication [0.03%]
从SARS-CoV-2的发现其基因组结构、转录和复制
Ayslan Castro Brant,Wei Tian,Vladimir Majerciak et al.
Ayslan Castro Brant et al.
SARS-CoV-2 is an extremely contagious respiratory virus causing adult atypical pneumonia COVID-19 with severe acute respiratory syndrome (SARS). SARS-CoV-2 has a single-stranded, positive-sense RNA (+RNA) genome of ~ 29.9 kb and exhibits si...
Differing susceptibility of C57BL/6J and DBA/2J mice-parents of the murine BXD family, to severe acute respiratory syndrome coronavirus infection [0.03%]
不同寻常的易感性C57BL/6J和DBA/2J小鼠：BXD家系的小鼠父母对严重急性呼吸系统综合症冠状病毒的感染
Kui Li,Yang Shen,Mark A Miller et al.
Kui Li et al.
The ongoing coronavirus disease-2019 (COVID-19) pandemic, caused by a novel coronavirus termed severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that is closely related to SARS-CoV, poses a grave threat to global health and has d...
Correction to: Aldose reductase deficiency inhibits LPS-induced M1 response in macrophages by activating autophagy [0.03%]
Correction to: 己糖还原酶缺乏通过激活自噬抑制LPS诱导的巨噬细胞M1型反应
Peng Cheng,Jianwei Xie,Zhiyong Liu et al.
Peng Cheng et al.
Published Erratum
Cell & bioscience. 2021 Jul 18;11(1):135. DOI:10.1186/s13578-021-00652-y 2021
Lung branching morphogenesis is accompanied by temporal metabolic changes towards a glycolytic preference [0.03%]
肺分支形态发生伴随着向糖酵解偏好的代谢变化
Hugo Fernandes-Silva,Marco G Alves,Henrique Araújo-Silva et al.
Hugo Fernandes-Silva et al.
Background: Lung branching morphogenesis is characterized by epithelial-mesenchymal interactions that ultimately define the airway conducting system. Throughout this process, energy and structural macromolecules are neces...
Assessment of changes in autophagic vesicles in human immune cell lines exposed to nano particles [0.03%]
纳米颗粒暴露下人类免疫细胞系自噬小体变化的评估
Christopher A W David,M Estela Del Castillo Busto,Susana Cuello-Nuñez et al.
Christopher A W David et al.
Background: Safe and rational development of nanomaterials for clinical translation requires the assessment of potential biocompatibility. Autophagy, a critical homeostatic pathway intrinsically linked to cellular health ...
Pathological alterations in the gastrointestinal tract of a porcine model of DMD [0.03%]
DMD猪模型胃肠道病理改变
Xiaodong Zou,Hongsheng Ouyang,Daxin Pang et al.
Xiaodong Zou et al.
Background: Patients with Duchenne muscular dystrophy (DMD) develop severe skeletal and cardiac muscle pathologies, which result in premature death. Therefore, the current therapeutic efforts are mainly targeted to correc...
YTHDF2 alleviates cardiac hypertrophy via regulating Myh7 mRNA decoy [0.03%]
YTHDF2通过调节Myh7 mRNA海绵缓解心室肥大
Hongfei Xu,Zhen Wang,Miao Chen et al.
Hongfei Xu et al.
Background: Pathological cardiac hypertrophy is a major contributor of heart failure (HF), which seriously threatens human's health world widely. Deregulation of m6A RNA methylation, and m6A methyltransferases and de-meth...
ADP/ATP translocase 1 protects against an α-synuclein-associated neuronal cell damage in Parkinson's disease model [0.03%]
线粒体ADP/ATP交换蛋白1通过减少α-突触核蛋白诱导的神经元损伤来保护帕金森病模型中的神经元细胞
Wenyong Ding,Minghua Qi,Li Ma et al.
Wenyong Ding et al.
Background: ADP/ATP translocase 1 (ANT1) is involved in the exchange of cytosolic ADP and mitochondrial ATP, and its defection plays an important role in mitochondrial pathogenesis. To reveal an etiological implication of...
Rev-erbα exacerbates hepatic steatosis in alcoholic liver diseases through regulating autophagy [0.03%]
Rev-erbα通过调节自噬加重酒精性肝病中的肝脏脂质沉积
Qingxue Liu,Lei Xu,Meifei Wu et al.
Qingxue Liu et al.
Background and aims: Alcoholic fatty liver (AFL) is a liver disease caused by long-term excessive drinking and is characterized by hepatic steatosis. Understanding the regulatory mechanism of steatosis is essential for th...