Axon regeneration after optic nerve injury in rats can be improved via PirB knockdown in the retina [0.03%]
通过视网膜PirB基因干扰改善大鼠视神经损伤后的轴突再生
Mei Yang,Lan Jian,Wei Fan et al.
Mei Yang et al.
Background: In the central nervous system (CNS), three types of myelin-associated inhibitors (MAIs) exert major inhibitory effects on nerve regeneration: Nogo-A, myelin-associated glycoprotein (MAG), and oligodendrocyte-m...
Retraction Note to: Roles of the PI3K/AKT/mTOR signalling pathways in neurodegenerative diseases and tumours [0.03%]
撤回 notice:PI3K/Akt/mTOR 信号通路在神经退行性疾病和肿瘤中的作用
Fei Xu,Lixin Na,Yanfei Li et al.
Fei Xu et al.
Retraction of Publication
Cell & bioscience. 2021 Aug 6;11(1):157. DOI:10.1186/s13578-021-00667-5 2021
FOXD1 promotes EMT and cell stemness of oral squamous cell carcinoma by transcriptional activation of SNAI2 [0.03%]
FOXD1通过转录激活SNAI2促进口腔鳞状细胞癌上皮间质转化和细胞干性
Yang Chen,Weilian Liang,Ke Liu et al.
Yang Chen et al.
Background: Epithelial-mesenchymal transition (EMT) and cell stemness are implicated in the initiation and progression of oral squamous cell carcinoma (OSCC). Revealing the intrinsic regulatory mechanism may provide effec...
Modaline sulfate promotes Oct4 expression and maintains self-renewal and pluripotency of stem cells through JAK/STAT3 and Wnt signaling pathways [0.03%]
_MODALINE通过JAK/STAT3和Wnt信号通路促进OCT4表达并维持干细胞自我更新和多能性
Xianglin Mei,Hanhan Zhao,Huihan Ai et al.
Xianglin Mei et al.
Background: Stem cells have been extensively explored for a variety of regenerative medical applications and they play an important role in clinical treatment of many diseases. However, the limited amount of stem cells an...
ADAMTS-1: a novel target gene of an estrogen-induced transcription factor, EGR1, critical for embryo implantation in the mouse uterus [0.03%]
Adamts1是雌激素诱导的转录因子Egr1调控的新的基因，对小鼠子宫胚胎着床至关重要
Mira Park,So Hee Park,Hyunsun Park et al.
Mira Park et al.
Background: Recently, we demonstrated that estrogen (E2) induces early growth response 1 (Egr1) to mediate its actions on the uterine epithelium by controlling progesterone receptor signaling for successful embryo implant...
Regulation of neuropeptide Y in body microenvironments and its potential application in therapies: a review [0.03%]
神经肽Y在机体微环境中的调控及其潜在治疗价值：综述研究
Yan Zhang,Chu-Yun Liu,Wei-Can Chen et al.
Yan Zhang et al.
Neuropeptide Y (NPY), one of the most abundant neuropeptides in the body, is widely expressed in the central and peripheral nervous systems and acts on the cardiovascular, digestive, endocrine, and nervous systems. NPY affects the nutrition...
Effects of low lead exposure on sperm quality and sperm DNA methylation in adult men [0.03%]
低血铅水平对男性精子质量和DNA甲基化的影响
Tiancheng Zhang,Yan Fei Ru,Bin Wu et al.
Tiancheng Zhang et al.
Instruction: Lead (Pb) exposure is a risk factor for male infertility, but the epigenetic changes in sperm DNAattributable to lead exposure is poorly defined. ...
EHMT2 promotes the pathogenesis of hepatocellular carcinoma by epigenetically silencing APC expression [0.03%]
EHMT2通过表观遗传学沉默APC表达促进肝细胞癌的发生发展
Yuan Guo,Yan-Rong Zhao,Huan Liu et al.
Yuan Guo et al.
Background: Hepatocellular carcinoma (HCC), the second leading cause of cancer death worldwide, alone accounts for over half (466,100) of new cancer cases and 422,100 deaths based on the average year incidence rates of 20...
Wenhua Su,Qian Huo,Hao Wu et al.
Wenhua Su et al.
Cardiac hypertrophy, characterized by the enlargement of cardiomyocytes, is initially an adaptive response to physiological and pathological stimuli. Decompensated cardiac hypertrophy is related to fibrosis, inflammatory cytokine, maladapti...
TRIM28 inhibits alternative lengthening of telomere phenotypes by protecting SETDB1 from degradation [0.03%]
TRIM28通过保护SETDB1不被降解来抑制端粒选择性延长表型
Chuanle Wang,Zhou Songyang,Yan Huang
Chuanle Wang
Background: About 10-15% of tumor cells extend telomeres through the alternative lengthening of telomeres (ALT) mechanism, which is a recombination-dependent replication pathway. It is generally believed that ALT cells ar...