Aryl hydrocarbon receptor-mediated transcriptional regulation of HSP70 exacerbates endoplasmic reticulum stress in lupus nephritis [0.03%]
芳烃受体介导的HSP70转录调控加剧狼疮性肾炎内质网应激反应
Min Wen,Jian Li,Yongzhen Li et al.
Min Wen et al.
Lactylation-related genes contribute to neurological injury and prognosis of acute ischemic stroke based on transcriptome and single-cell sequencing analysis [0.03%]
基于转录组和单细胞测序分析，乳酰化相关基因对急性缺血性卒中神经功能损伤及预后的影响
Jie Li,Lulu Zhu,Xiaolan Huang et al.
Jie Li et al.
Background: The rapid accumulation of lactate following cerebral ischemia has been well documented, however, the pathophysiological mechanisms underlying hyperlactate-induced lactylation in modulating neurological injury ...
Retraction Note: Autophagy-mediated degradation of NOTCH1 intracellular domain controls the epithelial to mesenchymal transition and cancer metastasis [0.03%]
撤回 notice: 自噬介导的 notch1 细胞内结构域降解控制上皮到间质转化和癌症转移
Sahib Zada,Jin Seok Hwang,Trang Huyen Lai et al.
Sahib Zada et al.
Regulation of transcription by R loop-nucleated transcription condensate assembly [0.03%]
通过R环介导的转录凝聚组装调节转录
Raissa Regina Ng,Zhongyang Lin,Heng Wee Tan et al.
Raissa Regina Ng et al.
Prevalence of promoter paused R loops formed from frequent RNA PolII pausing in eukaryotic cells not only pose a significant threat to genomic stability, but also a potent regulator of transcription. In this review, we discuss how R loops a...
LncRNA HOXC-AS3 prevents chondrocyte senescence and osteoarthritis progression through miR-615-3p sponging and RRBP1 interaction [0.03%]
长链非编码RNA HOXC-AS3通过海绵吸附miR-615-3p和与RRBP1相互作用来防止软骨细胞衰老和骨关节炎进展
Chan Wang,Jun Zhou,Lulu Chen et al.
Chan Wang et al.
Background: Osteoarthritis (OA) is a widespread chronic joint disorder characterized by progressive cartilage degeneration, leading to substantial impairment in quality of life for millions of individuals globally. Cellul...
The impact and mechanisms of preeclampsia on offspring neurodevelopment [0.03%]
子代神经发育受妊娠期高血压影响及其机制研究
Ying Zhang,Li Bao,Ke-Zhi Li et al.
Ying Zhang et al.
The cytoskeleton regulates cytoophidium dynamics in Drosophila ovaries [0.03%]
细胞骨架调节果蝇卵巢中的细胞蛇状结构动态变化
Xiao-Jing Liu,Yi-Lan Li,Shu-Yu Pang et al.
Xiao-Jing Liu et al.
Cytoophidia are filamentous structures composed of CTP synthase (CTPS) and were first identified in the ovarian cells of Drosophila. As a highly conserved, membraneless organelle present across all three domains of life, cytoophidia exhibit...
M2 polarization of macrophage induced by IL-33 promotes mouse sciatic nerve regeneration [0.03%]
白细胞介素-33诱导的巨噬细胞M2极化促进坐骨神经再生
Danyang Xu,Yanyi Li,Qi Zhang et al.
Danyang Xu et al.
Lactylation-related gene signature as a prognostic biomarker for neuroblastoma: insights into tumor progression and immune modulation [0.03%]
乳酰化相关基因特征作为神经母细胞瘤预后生物标志物的潜在作用：肿瘤进展和免疫调节的新见解
Jiangquan Zhu,Muyang Luo,Li Yuan et al.
Jiangquan Zhu et al.
Background: Lactylation, a recently identified post-translational modification mediated by lactate, plays a critical role in regulating metabolic and immune processes in tumors. However, its function in neuroblastoma, par...
Targeting epigenetic regulators to boost T cell immunotherapy against cancer [0.03%]
表观遗传调控在T细胞免疫治疗中的作用及机制研究
Tiaojiang Xiao,Ying E Zhang
Tiaojiang Xiao
Epigenetic regulation is crucial in directing T-cell differentiation, function, and fate, thereby influencing the success of T-cell-based immunotherapies. This review begins with an overview of the evolution of T-cell immunotherapies in can...