Spontaneous whole genome duplication renders mouse embryonic fibroblasts resistant to reprogramming [0.03%]
自发性的基因组倍增使成纤维细胞抗拒重编程序化
Wei Li,Lingyu Zhong,Pengli Li et al.
Wei Li et al.
Microglial HDAC3 inhibits the migration of CD8-positive T cell in the development of EAE by restraining the expression of CCL5 [0.03%]
小胶质细胞HDAC3通过抑制CCL5表达限制CD8阳性T细胞在自身免疫性脑脊髓炎发病过程中的迁移
Na Che,Yang Zhang,Bo Wang et al.
Na Che et al.
The molecular mechanism underlying the differential subcellular distribution of dystrophin Dp71 isoforms [0.03%]
Duchenne营养不良蛋白Dp71异种体不同亚细胞分布的分子机制
Alma Alamillo-Iniesta,Griselda Velez-Aguilera,Feliciano Monterrubio-Ledezma et al.
Alma Alamillo-Iniesta et al.
Background: Dystrophin Dp71 is a versatile protein that plays a critical role in regulating diverse processes, including cell adhesion, nuclear architecture, neuronal differentiation, and synapse organization. Moreover, D...
Regulation of oncogenic C-terminal truncated p53β protein isoform expression by SRSF3-UPF1 splicing and surveillance axis [0.03%]
SRSF3-UPF1剪接和监视轴调控致癌型p53β蛋白异构体表达
Jiwon Jeong,Dawon Hong,Tae Young Park et al.
Jiwon Jeong et al.
Dysregulated expression of tumor suppressor genes can impair their functions, even promoting oncogenesis. Expression of p53β mRNA can be regulated by alternative splicing and RNA surveillance, otherwise translated to a C-terminal truncated...
The role of stem cells and their engineering strategies in the repair of nerve damage in intracerebral hemorrhage [0.03%]
干细胞及其工程策略在脑出血后神经损伤修复中的作用
Liangzhe Wei,He Ren,Yuanwei Lin et al.
Liangzhe Wei et al.
METTL3 stabilizes FASN mRNA by mediating m6A modification to promote malignant progression of diffuse large B-cell lymphoma [0.03%]
METTL3通过介导m6A修饰稳定FASN mRNA促进弥漫性大B细胞淋巴瘤恶性进展
Xiangxiang Song,Yun Zhong,Nasha Yu et al.
Xiangxiang Song et al.
Background: Diffuse large B-cell lymphoma (DLBCL) is an aggressive subtype of non-Hodgkin lymphoma. Fatty acid synthase (FASN) is a key lipogenic enzyme implicated in tumor progression, but its regulation in DLBCL is poor...
Semi-automated isolation of parenchymal and non-parenchymal liver cells from mice and humans with enhanced stellate cell fraction [0.03%]
改良型星状细胞分离小鼠和人类肝实质与非实质细胞的半自动隔离方法
Anne Dropmann,Bedair Dewidar,Kerry Gould et al.
Anne Dropmann et al.
Sevoflurane induces developmental cardiotoxicity via AMPKα2 dysregulation in zebrafish [0.03%]
异氟醚通过AMPKα2调节异常诱导斑马鱼发育期心脏毒性
Huiyu Hao,Yuanhao Li,Xiaoyu Li et al.
Huiyu Hao et al.
Sevoflurane, a widely used volatile anesthetic, has raised concerns regarding its potential developmental toxicity, particularly due to its extensive application in non-obstetric surgeries and fetal intervention procedures during pregnancy....
Correction: RNF186 controls glucose metabolism in metabolic dysfunction-associated fatty liver disease [0.03%]
Correction: RNF186调控代谢功能紊乱相关脂肪性肝病中的葡萄糖代谢
Jiang Du,Qizhang Du,Yuxuan Zhang et al.
Jiang Du et al.
Published Erratum
Cell & bioscience. 2026 Mar 11;16(1):29. DOI:10.1186/s13578-026-01545-8 2026
CASC19 stabilization by ALYREF via m5C modification and its impact on SCD in colorectal cancer cell aggressiveness and stemness [0.03%]
通过m5C修饰的ALYREF稳定CASC19及其对结直肠癌细胞侵袭性和干细胞特性中SCD的影响
Li Zhao,Rongjun Xie,Li Li et al.
Li Zhao et al.
The progression of colorectal cancer (CRC) is closely associated with aberrant epigenetic regulation. As a key regulator of m5C modification, the role and mechanism of Aly/REF export factor (ALYREF) in CRC remain unclear. This study aims to...