Jessica E Maxwell,James R Howe
Jessica E Maxwell
Neuroendocrine tumors are a heterogeneous group of neoplasms that are best worked up and managed using a variety of clinical and imaging studies. They are often diagnosed after they have already metastasized, though this does not necessaril...
Maria E Cabanillas,Mimi I Hu,Camilo Jimenez et al.
Maria E Cabanillas et al.
Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor deriving from the thyroid parafollicular cell. Thyroidectomy continues to serve as the primary initial treatment for this cancer. Because standard cytotoxic chemotherapy has p...
Exploring the tumors of multiple endocrine neoplasia type 1 in mouse models for basic and preclinical studies [0.03%]
用于基础和临床前研究的MEN1小鼠模型及其肿瘤分析
Sunita K Agarwal
Sunita K Agarwal
Most patients (70-90%) with the multiple endocrine neoplasia type 1 (MEN1) syndrome possess germline heterozygous mutations in MEN1 that predisposes to tumors of multiple endocrine and nonendocrine tissues. Some endocrine tumors of the kind...
Rachel D Aufforth,Naris Nilubol
Rachel D Aufforth
Adrenocortical carcinoma (ACC) is a very rare and aggressive tumor with dismal outcomes. Best current treatments include complete surgical resection for localized resectable disease and systemic therapy with mitotane alone or in combination...