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Exploring the tumors of multiple endocrine neoplasia type 1 in mouse models for basic and preclinical studies

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Most patients (70-90%) with the multiple endocrine neoplasia type 1 (MEN1) syndrome possess germline heterozygous mutations in MEN1 that predisposes to tumors of multiple endocrine and nonendocrine tissues. Some endocrine tumors of the kinds seen in MEN1 that ... ...