Continuation of first-line therapy with radiotherapy for oligoprogression versus early switch to second-line therapy in oligoprogressive hepatocellular carcinoma (CROSS): study protocol of a multicentre, randomised, controlled, open-label, phase III trial [0.03%]
局部放射治疗延续一线治疗与替诺福韦或/和免疫检查点抑制剂二线治疗寡进展性肝细胞癌的疗效比较:一项多中心、随机、对照、开放标签、三期临床试验(CROSS)研究方案
Haohua Wang,Fang Shi,Xiang Zhang et al.
Haohua Wang et al.
Introduction: Treatment options remain limited for patients with advanced hepatocellular carcinoma (HCC) who experience oligoprogression during first-line systemic therapy (FLST), especially given the modest efficacy and ...
Anxiety, depression and post-traumatic stress disorder in displaced and non-displaced individuals after armed conflict: cross-sectional survey evidence from Kasai, Democratic Republic of Congo [0.03%]
刚果民主共和国卡萨伊地区武装冲突后流离失所者和未流离失所者的焦虑、抑郁和创伤后应激障碍的横断面调查证据
Nik Stoop,Peter van der Windt,Sigrid Weber et al.
Nik Stoop et al.
Objectives: The study aims to estimate the prevalence of anxiety, depression and post-traumatic stress disorder (PTSD) in the Greater Kasai region of the Democratic Republic of the Congo (DRC) and to examine how demograph...
HIV self-testing for partners of postpartum women to facilitate HIV pre-exposure prophylaxis and antiretroviral therapy uptake: a protocol to adapt and pilot an intervention via a pilot randomised controlled trial in South Africa [0.03%]
一种简化适应型干预措施的试点试验方案:通过给南非洲产后妇女的伴侣提供HIV自我检测,从而促进HIV暴露前预防及抗逆转录病毒疗法的采用
Christina Psaros,Ivana Beesham,Nzwakie Mosery et al.
Christina Psaros et al.
Introduction: South African women are vulnerable to HIV acquisition during the postpartum period which can result in perinatal transmission via breastfeeding; many male partners do not know their HIV status. Biomedical ap...
Randomized Controlled Trial
BMJ open. 2026 Jun 9;16(6):e121917. DOI:10.1136/bmjopen-2026-121917 2026
Catering to patients with Parkinson's disease: a survey on self-perceived competence and barriers of speech and language pathologists in Malaysia [0.03%]
马来西亚帕金森氏症患者的沟通需要:语言病理学家自身的专业能力与障碍因素调查研究
Giuditta Smith,Nursabrina Binti Kamarulzaman,Ching Sin Siau et al.
Giuditta Smith et al.
Objective: Referrals to speech and language pathology are infrequent for people with Parkinson's disease (PD), despite speech and communication being often affected and greatly impacting their quality of life. This study ...
Menopause age and hypercholesterolemia comorbidities: a region-wide retrospective cohort study in Andalusia, Spain (2016-2022) [0.03%]
绝经年龄与高胆固醇并存关系:西班牙安达卢西亚地区(2016-2022)一项回顾性队列研究
Alberto Esteban-Medina,Víctor de la Oliva,Patricia Fernández Del Valle et al.
Alberto Esteban-Medina et al.
Objectives: To quantify sex- and age-related differences in hypercholesterolaemia diagnosis and associated comorbidities around the menopausal transition, using a population-based real-world dataset. ...
Observational Study
BMJ open. 2026 Jun 9;16(6):e101587. DOI:10.1136/bmjopen-2025-101587 2026
School-based versus community-based interventions for promoting mental health among school-age children in marginalised or underserved populations: a systematic review protocol [0.03%]
针对边缘化或服务不足人群中小学生的学校内与社区内心理健康促进干预措施的系统评价方案
Nelson Ositadimma Oranye,Asseged Dibaba,Ignatius Uche Nwankwo et al.
Nelson Ositadimma Oranye et al.
Introduction: School-aged children frequently experience psychological distress due to academic pressures, a challenge that is often more severe for those from underserved and minority communities. This study aims to eval...
Transcutaneous auricular vagus nerve stimulation for moderate to severe chronic prostatitis/chronic pelvic pain syndrome (TASC-P) in China: study protocol for a randomised controlled trial [0.03%]
中国耳迷走神经贴片刺激治疗中重度慢性前列腺炎/慢性骨盆疼痛综合征(TASC-P):随机对照试验方案
Xinyao Wei,Jiaming Cui,Zhiwei Zang et al.
Xinyao Wei et al.
Introduction: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) affects around 35%-50% of men during their lifetime. The efficacy of current oral medication for CP/CPPS remains limited. Recent studies demonstrate...
Electronic nicotine delivery systems versus nicotine replacement therapies and risk of smoking relapse: evidence from a US nationwide prospective cohort (Cancer Prevention Study-3) [0.03%]
电子尼古丁输送系统与尼古丁替代疗法及吸烟风险的关系:来自美国全国前瞻性队列(Cancer Prevention Study-3)的证据
Johann L Westmaas,Mariah Landry,Tyler Nighbor et al.
Johann L Westmaas et al.
Objective: To compare use of electronic nicotine delivery systems (ENDS) with nicotine replacement therapies (NRTs) on risk of cigarette smoking relapse by people who had already quit cigarettes. ...
Comparative Study
BMJ open. 2026 Jun 9;16(6):e111672. DOI:10.1136/bmjopen-2025-111672 2026
Consultation-Liaison psychiatry in a high-complexity university hospital in Turin, Italy: an observational study with a focus on delirium and predictive factors of clinical outcome [0.03%]
意大利都灵一所复杂程度较高的大学附属医院的精神病 Consult-Lian 诊疗:一项以谵妄及临床结果预测因素为重点的观察性研究
Paola Bozzatello,Roberta Novelli,Rebecca Schisano et al.
Paola Bozzatello et al.
Background and aim: This observational study aims to provide an overview of consultation-liaison psychiatry (CLP) activity within the high-intensity, complex hospital setting of the 'Azienda Ospedaliera Universitaria Citt...
Observational Study
BMJ open. 2026 Jun 9;16(6):e111863. DOI:10.1136/bmjopen-2025-111863 2026
Drivers of youth mental health and wellbeing: a large-scale cross-sectional study in Morocco [0.03%]
摩洛哥一项大规模横断面研究:青年精神健康和幸福感的影响因素
Jihad Bnimoussa,Oumnia Bouaddi,Imad El Badisy et al.
Jihad Bnimoussa et al.
Objectives: This study aimed to describe the factors influencing mental health and wellbeing from the perspective of Moroccan youth. Design: ...